Medical Conditions in Pregnancy (OLD NOTES) Flashcards

(47 cards)

1
Q

What things are done at a normal ANC booking visit?

A
  • General pregnancy advice is given.
  • Identify if low/high risk.
  • Information on choices for place of delivery.
  • Discuss screening.
  • Check height and weight (BMI).
  • Check BP.
  • Arrange dating USS at 12 weeks.
  • Arrange ‘booking’ bloods.
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2
Q

What bloods are taken at booking, and what is screened for via blood testing?

A
  • FBC and Blood Group and Antibodies (Rh status)
  • Haemaglobinopathies
  • Infection Screen - Hep B, HIVm rubella, VDRL
  • Random Blood Glucose - screen for diabetes
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3
Q

When is the first USS done?

A

11-12 weeks

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4
Q

When is the anomaly scan done?

A

20 weeks

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5
Q

Up to how many weeks are monthly visits done?

A

28 weeks

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6
Q

When is anti D checked?

A

28 weeks + 34 weeks

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7
Q

When are weekly visits done?

A

37 weeks until delivery

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8
Q

What is done at every antenatal visit?

A
  • Accurately document gestation.
  • BP.
  • Urinalysis.
  • SFH (FSH).
  • Referral of any problems to Consultant Unit.
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9
Q

What is the commonest medical problem in pregnancy?

A

HYPERTENSION

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10
Q

What is defined as chronic essential hypertension in pregnancy?

A

HTN present at booking or <20weeks

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11
Q

What is gestational hypertension defined as?

A

New HTN >20weeks without significant proteinuria.

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12
Q

What is pre-eclampsia defined as?

A

New HTN >20weeks + significant proteinuria.

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13
Q

What 5 factors do you need to consider in someone with suspected hypertension?

A
  1. Effect on pregnancy.
  2. Pregnancy effect.
  3. Medications.
  4. Delivery.
  5. Post-partum.
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14
Q

Outline 3 factors which contribute to decreased blood flow to organs.

A
  1. Vasoconstriction
  2. Pro-coagulation
  3. Intravascular thrombosis
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15
Q

What happens to GFR? (in pregnancy-induced renal disease)?

A

It decreases

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16
Q

What happens to serum uric acid? What may be associated with this? (in renal disease in pregnancy)

A

It increases

There is also placental ischaemia

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17
Q

What 3 things increase in renal disease in pregnancy?

A
  1. Creatinine
  2. Potassium
  3. Urea
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18
Q

What happens to urine output in a pregnancy lady with renal disease?

A

There is oliguria/anuria (small amounts of urine or no urine)

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19
Q

What 2 categories can acute renal failure be divided into?

A
  1. Acute tubular necrosis.

2. Renal cortical necrosis.

20
Q

What symptoms may a pregnant woman with liver disease experinece?

A

Epigastric/RUQ pain

21
Q

What – on investigation – may be abnormal, in a pregnant lady with liver disease?

A

Liver enzymes

22
Q

What serious condition can arise from liver disease in pregnancy?

A

HEPATIC CAPSULE RUPTURE

23
Q

What may hepatic capsule rupture/ liver disease in pregnancy lead to?

A

HELLP Syndrome – haemolysis, elevated liver enzymes, low platelets.

24
Q

Give 3 problems associated with placental disease.

A
  • IUGR.
  • Placental abruption.
  • Intrauterine death.
25
What investigations should be done for hypertension in pregnancy?
* Urea and electrolytes. * Serum urate. * LFT’s. * FBC. * Coagulation screen. * CTG. * Ultrasound – biometry, AFI, Doppler.
26
At what points in the pregnancy journey should the mx of HT be considered?
* Pre-conception. * Booking. * Antenatal. * Intrapartum. * Postpartum.
27
If, on assessment at booking or at any other point antenatally, there are risk factors for pre-eclampsia, what should be done?
GIVE ASPIRIN
28
If, on assessment at booking or at any other point antenatally, there are risk factors for pre-eclampsia, what should be done?
Surveillance - Scans. - BP monitoring. - Urine testing. - Staff: medical, midwives, community
29
If a woman has hypertension at < 20 weeks, what should you do?
Check for a secondary cause - it is VERY likely that she already had hypertension
30
What medications are used to treat HT in pregnancy? (list these in order of 1st, 2nd line etc)
1. Labetalol. 2. Methyldopa. 3. Nifedipine (usually if monotherapy fails ie. top up).
31
What anti-hypertensive medication should be stopped in pregnancy?
ACEI’s and ARB’s
32
What can be used for severe hypertension in pregnancy?
* Labetalol (oral or IV). * Hydralazine (IV). * Nifedipine (oral).
33
165/110 would be classified as ______ hypertension in pregnancy
severe
34
What is the target BP in pregnancy?
150/80-100mmHg
35
If there is target organ damage, e.g. renal damage, causing proteinuria or retinal damage, what BP should you aim for?
<140/90mmHg.
36
If BP is i) <140/90 ii) <130/90mmHg, what should you do?
i) Consider reducing dose. | ii) Reduce dose.
37
What are the effects of pregnancy on diabetes?
Pregnancy is DIABETOGENIC * poorer control * deterioration of renal function * deterioration of ophthalmic disease * GDM
38
What are the effects of diabetes on pregnancy?
* Miscarriage. * Foetal malformations: cardiac, neural tube defects, caudal regressions syndrome. * IUGR/Macrosomia. * Unexplained IUD. * PET.
39
How can diabetes in pregnancy be managed?
Diet, metformin or insulin
40
What type of delivery should be aimed for in diabetes?
Vaginal delivery – induce labour at 37-38 weeks
41
What type of diabetes can present in pregnancy?
* Pre-existing Type 1. * Pre-existing Type 2. (increasing) * Gestational Diabetes. (increasing).
42
Outline the effects of diabetes on the foetus.
1. Maternal diabetes – hyperglycaemia 2. Foetal hyperinsulinaemia 3. Increased foetal growth  foetal macrosomia  shoulder dystocia 4. Polyuria + Polyhydramnios, Increased O2 demands  risk of preterm labour, malpresentation and cord prolapse 5. neonatal hypoglycaemia  risk of cerebral palsy
43
Outline risk factors for GDM.
- Previous GDM. - FHx: one first degree, or two second degree relatives. - Poor obstetric history, esp. death of previous macrosomic baby. - Significant glycosuria. - Polyhydramnios. - Macrosomic infant in this pregnancy. - Polycystic ovary syndrome. - Weight >100kg or BMI>30. - South Asian, Middle Eastern or African origin.
44
HbA1C should be kept below what?
6%
45
What should be done every trimester in a woman with hypertension?
Retinal screening
46
When should serial growth scans be done in a pregnancy lady with hypertension?
At 28, 32 and 36 weeks.
47
What should be monitored for in pregnant ladies with hypertension?
PET