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2020 CSO Exam > Medication > Flashcards

Medication Flashcards

1
Q

Mirtazipine

A

Remeron, for depression and appetite, chemo related nausea

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2
Q

Movantik (naloxegol)

A

Used for chronic opioid induced constipation

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3
Q

Nivolumab (Opdivo)

A

IV- immunotherapy, 2x/wk, targeted cell therapy, monoclonal antibody drugs

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4
Q

Capetecabine (xeloda)

A

Met breast cancer, colon and rectal cancer

Antineoplastic chemotherapy

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5
Q

Sitravatinib

A

Molecular inhibitor of tyrosine kinase - experimental drug

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6
Q

Etoposide

A

Chemo for lymphoma

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7
Q

Chemo: cell cycle non specific- alkylating agents

A

stops DNA replication- highly emetogenic

Carboplatin, cisplatin, cyclophasphamide, dacarbazine, oxaliplatin, temozolomide

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8
Q

Chemo: cell cycle specific- antimetabolites

A

Stop DNA synthesis by acting like false metabolites

Capecitabine, fluorouracil (5-FU), gemcitabine methotrexate

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9
Q

Chemo: cell cycle specific-antitumor antibiotics

A

inhibits cell division by binding to DNA

Bleomycin,

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10
Q

Chemo: cell cycle specific- antitumor antibiotics anthracyclines

A

doxorubicin anthracyclines inhibits cell division by binding to DNA

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11
Q

Chemo: cell cycle specific-epipodophylltoxins

A

damages cells before mitosis

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12
Q

Chemo: cell cycle specific-taxanes

A

mitosis phase of cell taxol doxtaxel

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13
Q

Chemo: cell cycle specific-vinca alkaloids

A

disrupt spindle formation- vincristine

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14
Q

Chemo: cell cycle specific- monoclonal antibodies

A

target Her2 (trastauzamab herceptin) EGFR (cetuximab) RANKL

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15
Q

Biotherapy: monoclonal antibodies

A

activate pathways cause apoptosis

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16
Q

biotherapy: protein targeted therapy

A

interact with target proteins inside cells

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17
Q

biotherapy: angiogenesis inhibitors

A

bevacizumab (avastin) targets VEGF

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18
Q

biotherapy: cytokines

A

interleukin 2 or interferon

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19
Q

biotherapy: cancer vaccines

A

hpv vaccine

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20
Q

biotherapy: radiopharmaceuticals

A

nuclear medicine

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21
Q

hormone therapy: tamoxifen

A

(SERM)

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22
Q

hormone therapy: aromatase inhibitors

23
Q

Hormone therapy

24
Q

Alimta

A

350-1000 mcg folic acid and B12 injections

25
Cisplatin
highly emetogenic: delayed n/v: omega 3 and turmeric may increase benefit hydration important
26
carboplatin
highly emetogenic - delayed n/v
27
cyclophosphamide
3L water/day empty bladder 2-3x even at night
28
capecitabine (xeloda)
give with food and water, B6 (50-100 mg 2-3x/day may help hand foot syndrome)
29
cetuximab (erbitux)
magnesium and calcium could ddrop
30
Doxorubicin
omega 3, theanine, coq10 may benefit
31
gemcitabine
**
32
ifosfamide
**
33
fluorouracil
damages GI tract, melt ice chips ac/pc chemo to decrease muscositis, B6 to reduce hand foot syndrome
34
MTX
mouth sores and diarrhea likely- no multis with folic acid, damages GI tract, no alcohol
35
cytarabine
diarrhea
36
camptosar
diarrhea that can be treated with atropine, damages GI tract, omega 3 may reduce toxicity
37
oxaliplatin (eloxatin)
sensitive to cold; B6 for hand foot syndrome
38
Paclitaxel
omega 3 may reduce toxicity
39
procarbazine
avoid foods high in tyramine for 2 weeks after, avoid caffeine and alcohol
40
Tamoxifen
avoid antacids within 2 hrs, avoid CYP3a4 inducers (st johns wort, phenobarbital) and inhibitors (grapefruit juice, erythromycin) inhibitors increase drug action while inducers decrease
41
velcade
green tea makes less effective
42
zanosar (streptozocin)
alters glucose metabolism in patients
43
zometa (zoledronic acid)
500 mg calcium and 400 IU vit D
44
tamoxifen
melatonin may increase response
45
N/v meds prescribed
reglan (metoclopramide) dexamethasone, zofran, aprepitant NK1 receptor agonist
46
atropine helps diarrhea from what
irinotecan
47
colace
docusate
48
dulcolax
bisacodyl irritates and stimulates
49
senna
irritates and sstimulates
50
immodium
loperamide can help with diarrhea from irinotecan (inhibits peristalsis)
51
metamucil
bulks then stimulates peristalsis
52
miralax
osmotic causes peristalsis
53
MOM
draws waters and stimulate peristalsis
54
Mg Citrate
draws water and stimulates peristalsis

2020 CSO Exam (32 decks)

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