Medications for Neuropathic Pain Flashcards by Chrissa Constantinides | Brainscape

Q

Central Sensitization - 1 (calcium channels)

A

Occurs in the dorsal horn on the SC
Release of excitatory NT’s (incl. glutamate & substance P)
Increased Ca2+ transport causes spontaneous impulses (APs)
pain message sent to brain
Medication that decrease Ca channel activity:
GBP: Gabapentin (precursor to Pregabalin)
PreGab: Pregabalin

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Q

What are #1 drugs for neuropathic pain?

A

Gabapentin & Pregabapentin

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Q

Central Sensitization

A

??ADD?

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Q

Central Sensitization - 2 (NMDA receptor)

A

??ADD

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Q

Central Sensitization

Ketamine

A

??ADD?

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Q

Central Sensitization

Dextromethorphan (

A

??ADD

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Q

Central Sensitization

Methadone

A

??ADD

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