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Flashcards in MEDS Deck (22):
1

Side effects of SSRI's

1. N/V/D
2. Agitation
3. Headache
4. Sexual Dysfunction, decreased libido and difficulty reaching orgasm
5. Headache
6. Insomnia/ anxiety (during initial activation)
7. Weight gain/ loss
8. Serotonin syndrome (excess serotonin) - serious, life threatening
9. High temperature
10. Dystonia
11. Diaphoresis
12. sleepiness
13. emotional flattening

2

What drug class do these drugs belong to?

Paroxetine (Paxil)
Escitalopram (Lexapro)
Fluoxetine (Prozac)

SSRI's

3

What drug class do Chlordiazepoxide (Librium), Lorazepam (Ativan) belong to?

Benzodiazepine

4

Indications for Paroxetine (Paxil):

Generalized Anxiety Disorder, Panic disorder

5

Indications for Escitalopram (Lexapro):

Generalized Anxiety Disorder

6

Indications for Fluoxetine (Prozac):

Body Dysmorphic Disorder

7

Indications for Chlordiazepoxide (Librium):

alcohol withdrawal;
sedative, hypnotic or anxiolytic withdrawal

8

What are the indications for Lorazepam (Ativan)?

GAD, social phobia, alcohol withdrawal;
sedative, hypnotic, or anxiolytic withdrawal

9

What are the indications for Dolophine (Methadone)?

synthetic opiate like drug - for opioid dependence

is an:
analgesic
antidiarrheal
antitussive
used in substitution therapy

10

What are the side effects for Dolophine (Methadone)?

respiratory depression
constipation
fecal impaction
hypotension
decreased libido
retarded ejaculation
impotence
orgasm failure

11

What are the indications for Naloxone (Narcan)?

opioid overdose b/c it is an opioid antagonist

12

What are the side effects for Naloxone (Narcan)?

increased HR
HTN
hypotension
n/v
tremor
withdrawal sx
diaphoresis
pulmonary edema
dyspnea

serious reactions:
ventricular fibrillation
cardiac arrest
seizures

13

What are the indications for Bupropion (Zyban) which inhibits the reuptake of norepi, serotonin, and dopamine?

nicotine use disorder (for smoking cessation)

comorbid depression and ADHD

major depression

14

What are the side effects for Bupoprion (Zyban) ?

headache
dizziness
insomnia
sedation
tachycardia
hypertension
dry mouth
n/v
weight gain or loss
seizure
constipation
tremor

15

What are the indications for Buprenorphine?

opioid withdrawal

16

What are the side effects for Buprenorphine?

sedation
headache
insomnia
pain (opioid dependency use)
withdrawal sx (opioid dependency use)
dizziness/vertigo
diaphoresis
nausea
constipation
rhinitis
asthenia
depression
anxiety
vasodilation
hypotension
hypoventilation

17

SSRI's are first line agents for _ __ _. They take __-__ weeks to reach symptom control.

chronic anxiety disorders; 3-4

18

SSRI's act on the __ system and indirectly on __

serotonin

GABA

19

Benzodiazepine Side effects

1. Drowsiness
2. Confusion
3. Lethargy
4. Tolerance
5. Psychological and physical dependence
6. Potentiates side effects of other CNS depressants (ETOH)
7. May aggravate symptoms of depression
8. Orthostatic hypotension
9. Paradoxical excitement
10. memory impairment
11. motor incoordination

20

SSRI's have shown some efficacy in decreasing impulsivity in __ __ __

borderline personality disorder

21

Benzodiazepines can be used for __ __ or __ __ disorder

sedative hypnotic
anxiolytic use

22

Buprenorphine is __ powerful than methadone but is considered to be somewhat __ and causes __ side effects

less
safer
fewer