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Flashcards in Meds Deck (39):
1

Steven Johnsons syndrome: disorder of the Skin and mucus membrane
Which drug should be started on low dosage?

Lamotrigine (Lamictal)

2

80 year old with progressive weakness.
CBC, UA, ESR are normal
High Creatinine Kinase
Cause?

Statin induced Myopathy!!!
PMR with give elevated ESR

3

Patient on parenteral Morphine, Increasing dose still in severe pain
DX and Tx?

Opioid induced hyperalgesia
- Morphine receptors are saturated!
- decrease morphine dose

4

How to minimize Lidocaine injection

Buffer with sodium bicarbonate

5

Guy with gynecomastia
Drug that can cause it?

Spirinolactone because it can bind to androgen and progesterone causing it

6

Post herpetic neuralgia
Tx?

Lidocaine patch

7

Prolong PPI Use
Risk?

Osteoporosis
H.Pylori infection

8

Urticaria: highly pruritic raised wheals on extremities and torso
TX?

H1- histamine blocker!
2nd gen are less drowsy!

9

Sympathomimetic decongestant like pseudoephedrine and phenlyephrine in elderly causes?

Worsen existing urinary obstruction

10

Iron def anemia with iron
How to improve iron absorption

Take Vit C

11

NSAID that least likely to increase risk of MI?

Naproxen
NSAID increases BP 2nd to salt and water retention properties

12

Meds that can cause Interstitial lung disease

Amiodarone
Nitrofurantoin - can induce pneumonitis

13

Egg allergy
What is the safest flu vaccine

Recombinant trivalent - no egg

14

Med that can lower the risk of pre eclampsia

Aspirin 60-80 mg daily

15

Preferred pain meds in ESRD?

Fentanyl - 99% hepatic metabolism

16

Medication with a higher risk of death due to stroke or sudden cardiac death in patients with dementia?

Seroquel ( Quetiapine)

17

Meds for Smoking Cessation?

Verenicline (chantix) can cause nightmares
Bupropion (Wellbutrin) - CI in seizures
Nortriptyline ( Pamelor)

18

Bisphophonate side effects in Osteoporosis

Can cause atypical femoral shaft fractures
- will not effect Vit D and phosphates

19

Class of diabetic medication that blocks glucose reabsorption by the kidneys causing GU infection?

SGLT2 inhibitors - Invokana

20

Patient with Hyperthyroidism with a low WBC count.
What meds can cause it?

Methimazole--> can cause agranulocytosis; can cause Inc fetal abnormalities

If pregnant, give PTU

21

55 y/o male with VF. Hx of antibiotic use 3 days ago

What antibiotic?

Azithromycin; can prolong QT --> VF

22

Medication that can be use for SVT that can be use Acutely and Long term?

CaCB- Verapamil

23

Pt with terminal cancer and Hepatic dysfunction has musculoskeletal and neuropathic pain, What medications should you avoid?

Methadone: metabolized and cleared by liver

24

Second Generation H1 Antihistamine that is sedating?

Cetirizine (Zyrtec) - potent histamine antagonist

25

NOAC with reversal?

Dabigatran(Pradaxa)--> Idarucizumab (Praxbind)

26

Female on Methimazole.

Adverse RON?

Agranulocytosis = hepatotoxic

27

Meds that is most effective for Alcohol relapse

Naltrexone

28

Antidepressant to avoid in the Elderly

Paroxetine --. More anticholinergic effects

1st line to give--> venlafaxine , Bupropion ( also good for smoking cessation), Mirtazapine

29

Patient with Gout attack and CKD stage 4!
TX?

1. Prednisone!

1st line: NSAID: Indomethacin -- but PT has CKD, Colchicine, Corticosteroids

Allopurinol and Probenacid are NOT advisable for Acute treatment; may be use to prevent attacks

30

44 y/o male started on Lisinopril
Has facial, lip and tongue edema
DX?
TX?

1. Angiodedema from Increased bradykinin not histamine!
2. Give Bradykinin receptor antagonist --> Icatibant (Firazyr)

31

Drugs that cause Bronchiolitis Obliterans Organizing Pneumonia?

Amiodarone + Bleomycin + Gold + MTX

32

Meds for travelers diarrhea if going to:
India?(S.Asia and SEA)?
South and Central America?

Azithromycin for SEA : for campylobacter
Cipro for Central America

33

Patient with DM
Found out to have low Vit B12
What meds caused it?

Metformin- decrease absorption by 30%

34

Patient with PE 2 weeks after surgery for uterine fibroids, no significant PMX
How long should the patient be on anticoagulant therapy?

3 months

35

Antiemetic drug that blocks domaine stimulation in the chemoreceptors trigger zone for gastroenteritis?

Metoclopramide

36

Drug that decreases Vit D levels in long term use

Phenytoin- increases metabolism of Vit D

Thiazides will increase Vit D

37

Side effects of colchicine?

Nausea, vomiting, diarrhea

38

Patient with Fibromyalgia.

What muscle relaxant can be used and why?

Med that can improve sleep, pain and well being?

Cyclobenzaprine- structurally like TCA; can increase inhibitory of serotonin and norepinephrine

Tramadol can be use for sleep, pain and well being

39

Risperidone side effects on female?

Elevated prolactin causing amenorrhea