Meds and Doses

Question 1

Cardiac conditions requiring SBE Prophylaxis

Answer 1

1. Prosthetic cardiac valve or prosthetic material used for cardiac valve repair
2. Previous infective endocarditis
3. Congenital heart disease (CHD) : Unrepaired cyanotic CHD, including palliative shunts and conduits, Completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first six months after the procedure, Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which inhibit endothelialization)
4. Cardiac transplantation recipients who develop cardiac valvulopathy

Question 2

Oral SBE prophylaxis dose: w/and w/o pencillin allegy

Answer 2

1. Amoxicililin or Cephalexin : 2 g (adults) and 50mg/kg (kids)
2. Clindamycin 600mg (adults) and 20mg/kg
3. Azithromycin/clarithromycin:500mg and 15mg/kg

Question 3

SBE prophylaxis unable to take oral medications

Answer 3

Ampicillin 2g IM/IV and 50mg/kg IM/IV

Cefazolin or cefriaxone 1g IM/IV and 50mg/kg

Question 4

Cephalexin dosage for children and adults

Answer 4

Children >1 yo : 50mg/kg/day divided dose every 8 hrs.

Adults: 500mg every 6 hours

Question 5

Clindamycin: dosage for children and adults

Answer 5

Children: 10mg/kg/day in 3-4 divided doses as hydrochloride

Adults : 300mg every 5 hrs

Question 6

Metronidazole: what might it be rx for? adult and adolescent dosage

Answer 6

Periodontal disease, including necrotizing ulcerative gingivitis:
- 500mg every 8 hours for 8 days

Question 7

Acetaminophen dosage for under and over 12 yo

Max doses?

Answer 7

12yo/adults: 400mg every 4-6 hrs prn

Max dose: 2.6g/day kids and 4g/day adults

Question 8

Ibuprofen: under and over 12yo and adults? max dose?

Answer 8

12 yo : 200mg every 4-6 hrs MAX 1.2g/day

Adult 200-400mg/every 4-6 max 1.2g/day

Question 9

Topical agents fro oral candidiasis?

Answer 9

Clotrimazole (10mg lozenge), miconazole (50mg buccal tablet), and nystatin (100kunit/mL suspension)

• Nystatin dosage: 1mL neonates, INfants 2mL and older 4-6mL swish 4xday for several minutes and swallow

Question 10

Systemic agents for oral candidaisis?

Answer 10

Fluconazole and Ketoconazole (adults200mg/day, kids 5mg/kg day)

Question 11

Topical agents for angular cheilitis?

Answer 11

Clotrimazole (cream 1%) Miconazole nitrate (cream 2%) nystatin (ointment)