Meds/Txs

Question 1

Histamine receptor antagonists that also have anti-muscarinic (sedation, anti-emetic), anti Na-channel (decrease in pain, and anti adrenergic receptor (orthostatic hypotension) action

Answer 1

1st generation anti-histamines - dimenhydrinate, diphenhydramine, meclizine

Question 2

dimenhydrinate, diphenhydramine, meclizine

Answer 2

1st generation Anti-Histamines - Histamine receptor antagonists that also have anti-muscarinic (sedation, anti-emetic), anti Na-channel (decrease in pain, and anti adrenergic receptor (orthostatic hypotension) action

Question 3

H1 receptor antagonist only, used for allergic rhinitis, decreased CNS penetration

Answer 3

2nd generation anti-histamines - loratidine, cetrizine, fexofenidine

Question 4

loratidine, cetrizine, fexofenidine

Answer 4

2nd generation anti-histamines - H1 receptor antagonist only, used for allergic rhinitis, decreased CNS penetration

Question 5

Stimulate alpha-1 receptors (vasoconstriction), used for allergic rhinitis/viral rhinitis, possibility for rebound congestion

Answer 5

Topical decongestants - phenylephrine, oxymetolazine

Question 6

phenylephrine, oxymetolazine

Answer 6

Topical decongestants - Stimulate alpha-1 receptors (vasoconstriction), used for allergic rhinitis/viral rhinitis, possibility for rebound congestion

Question 7

Stimulate alpha-1 receptors (vasoconstriction), used for allergic rhinitis/viral rhinitis. longer acting

Answer 7

Oral decongestants - pseudoephedrine, phenylephrine

Question 8

pseudoephedrine, phenylephrine

Answer 8

Oral decongestants - Stimulate alpha-1 receptors (vasoconstriction), used for allergic rhinitis/viral rhinitis. longer acting

Question 9

Binds mu-opioid receptors to suppress cough

Answer 9

Anti-tussives - codeine, hydrocodone, dextromethophan

Question 10

codeine, hydrocodone, dextromethophan

Answer 10

Anti-tussives - Binds mu-opioid receptors to suppress cough

Question 11

H1 histamine receptor antagonist used for cough

Answer 11

Diphenhydramine

Question 12

Thought to stimulate secretions in respiratory tract to be less viscous and easier to clear, debatable efficacy

Answer 12

Expectorant - Guaifenisin

Question 13

Guaifenisin

Answer 13

Expectorant - Thought to stimulate secretions in respiratory tract to be less viscous and easier to clear, debatable efficacy

Question 14

Splits disulfide bonds to make mucous less viscous, also used in aspirin overdose

Answer 14

Mucolytic - N-acetyl cysteine

Question 15

N-acetyl cysteine

Answer 15

Mucolytic - Splits disulfide bonds to make mucous less viscous, also used in aspirin overdose

Question 16

Bind beta-adrenergic receptors to promote bronchodilation and decrease secretions, used in asthma and COPD, has black box warning

Answer 16

Beta-adrenergic Agonists - albuterol, terbutaline, salmeterol, formoterol

Question 17

albuterol, terbutaline, salmeterol, formoterol

Answer 17

Beta-adrenergic Agonists - Bind beta-adrenergic receptors to promote bronchodilation and decrease secretions, used in asthma and COPD, has black box warning

Question 18

Inhibit muscarinic receptors promoting bronchodiliation and inhibiting secretions, used only in COPD

Answer 18

Anti-cholinergics - atropine, iprotropium, tiotropium

Question 19

atropine, iprotropium, tiotropium

Answer 19

Anti-cholinergics - Inhibit muscarinic receptors promoting bronchodiliation and inhibiting secretions, used only in COPD

Question 20

PLC inhibition and cytokine synthesis inhibition, anti-inflammatory, vasoconstrictive, used for acute exacerbations of asthma

Answer 20

Systemic glucocorticoids - prednisone, hydrocortisone, prednisololine, methylprednisolone

Question 21

prednisone, hydrocortisone, prednisololine, methylprednisolone

Answer 21

Systemic glucocorticoids - PLC inhibition and cytokine synthesis inhibition, anti-inflammatory, vasoconstrictive, used for acute exacerbations of asthma

Question 22

PLC inhibition and cytokine synthesis inhibition, anti-inflammatory, vasoconstrictive,, preferred long-acting control agent in asthma and COPD

Answer 22

Inhaled glucocorticoids - beclomethasone, dipropionate, triamcinolone, aceteonide

Question 23

beclomethasone, dipropionate, triamcinolone, aceteonide

Answer 23

Inhaled glucocorticoids - PLC inhibition and cytokine synthesis inhibition, anti-inflammatory, vasoconstrictive,, preferred long-acting control agent in asthma and COPD

Question 24

Bind beta-adrenergic receptors to promote bronchodilation and decrease secretions, preferred supplementary long-term treatment with inhaled GCS

Answer 24

Long-acting beta-adrenergic agonists (LABA) - salmeterol, formeterol

Question 25

salmeterol, formeterol

Answer 25

Long-acting beta-adrenergic agonists (LABA) - Bind beta-adrenerigic receptors to promote bronchodilation and decrease secretions, preferred supplementary long-term treatment with inhaled GCS

Question 26

LT D4 antagonist or 5-lipooxygenase inhibitor, bronchodilate and have anti-inflammatory effects, attenuates exercise-induced asthma

Answer 26

Leukotriene modifiers - montekulast, zafirlukast, zileuton

Question 27

montekulast, zafirlukast, zileuton

Answer 27

Leukotriene modifiers - LT D4 antagonist or 5-lipooxygenase inhibitor, bronchodilate and have anti-inflammatory effects, attenuates exercise-induced asthma

Question 28

Binds IgE to prevent IgE binding to mast cells, for allergic asthma, allergic rhinitis, subcutaneous

Answer 28

Immunomodulators - anti-ige (omalizumab)

Question 29

omalizumab

Answer 29

Immunomodulators - Binds IgE to prevent IgE binding to mast cells, for allergic asthma, allergic rhinitis, subcutaneous

Question 30

Inhibits mast cell mediator release, rarely prescribed anymore, inhaled, prevent exercise-induced asthma and allergic pulmonary response

Answer 30

cromolyn/nedocromil

Question 31

cromolyn/nedocromil

Answer 31

Inhibits mast cell mediator release, rarely prescribed anymore, inhaled, prevent exercise-induced asthma and allergic pulmonary response

Question 32

PDE inhibitor resulting in bronchodilation and some anti-inflammatory effects, narrow therapeutic window with many DDIs

Answer 32

Theophylline

Question 33

Theophylline

Answer 33

PDE inhibitor resulting in bronchodilation and some anti-inflammatory effects, narrow therapeutic window with many DDIs