Membranes and Transport Flashcards Preview

MCM private > Membranes and Transport > Flashcards

Flashcards in Membranes and Transport Deck (12):

What are the 2 different types of Phospholipids? Give examples

Glycerophospholipids: Phosphatidylserine, Phosphatidylcholine
Sphingolipids: Sphingomyelin


Glycolipids: Structure and location

Sphingosine backbone and carbohydrate residues. Found in the outer leaflet of the lipid bilayer.


On which sheet of the Plasma membrane are Phosphatidylcholine, Glycolipids, and Sphingomyelin located? (inner or outer?)

On the outer side of the membrane.


On which sheet of the Plasma membrane are Phosphatydilserine, Phosphatydilinositol and Phosphatydillethanolamine located? (inner or outer)?

Inner side of the membrane


Niemann-Pick Disease

Caused by deficiency of Sphingomyelinase. Sphingomyelin is accumulated and causes enlarged liver, and spleen and causes neurological problems.
Also called "cherry red spot"


Glycocalix: definition and functions

It is a carbohydrate cell.
It's functions are: Protection, Cell adhesion and cell identification.


Erythroblastis fetalis

Disease in which incompatibility between the mother(Rh-) and the fetus blood (Rh+)


Spur cell Anemia

It is a type of hemolytic anemia. It is caused by high levels of cholesterol in RBC membrane. Decreases fluidity and flexibility of membrane.


What is Mimantine/Namenda?

Antagonist of Glutamate receptor used to treat Alzheimer's disease.


Is the ATP hydrolyzed in the ABC Transporters?

Yes, but it does not phosphorylate the protein. E.g.: glycoproteins.



caused by a defect in the transport responsible for uptake of dimeric amino acid Cystein and the dibasic amino acids: Arg, Lys, and Ornithine. Result in the formation of Cysteine stones in the kidney.


Hartnup Disease

Caused by a defect in the transport of non polar Amino acids, specifically Trp. Transporter is found in the intestine and kidney primarily.
AKA Pellagra like dermatitis.