Memory And Cognition Flashcards
What are the types of non declarative memory
Procedural- skill learning
Associative- stimulus e.g classical conditioning
Non associative- habitual or sensitisation
What is hebbs law
???
Retrograde amnesia
Loss of memory for past events before trauma
Anterograde amnesia
Loss of ability to form new memories after trauma
Symptoms of patient HM
Coudldnt form new declarative memory
Lost memories for events few years before operation
Could remember childhood memories and learn procedural tasks
Shows medial temporal lobes are important in new declarative memory formation
How does Alzheimer’s cause dementia
Build up of aggregates of tau protein and others that causes neurons to die in medial temporal lobes
What structures are part of medial temporal (declarative memory)
Hippocampus -item in contex
Ec- linked to all
perirhinal cortex-what is item
Parahippocampal cortex-where is item in environment
Role of diencephalon and contents
Processing declarative memory
Thalamus
Hypothalamus
Anterior nuclei
Dorsal medial nuclei
Mammillary bodies
Routes from medial temporal
- Fornix-hypothalamus-anterior nucleus-cingulate cortex
2.dorsomedial nucleus-frontal cortex
What did patient NA show us
Evidence of diencephalon role in episodic memory
Lesion caused anterograde and retrograde (2yrs) amnesia
Role of hippocampus in spatial memory
Location and relationship between positions and location
How do parts of the diencephalon contribute to memory
Hippocampus and thalamus important for encoding or forming memories
Association cortcies are responsible for long term consolidation of episodic and semantic info
Theory that through regorganisation of hippocampus and thalamus connections between regions are strengthened until memory can be accessed independently of hippocampus
How is memory consolidated
Replay of experience dependant neuronal activity support memory consolidation
Replaying during rest or sleep
Where is important for non declarative memory
Striatum
Caudate nucleus
Putamen
Motor planning and generating movement
How does Parkinson’s effect memory
Caused by generation of dopaminergif inputs from substansia nigra into striatum
Impairs movement and procedural and association memories
