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Endocrinology > MEN & APES > Flashcards

MEN & APES Flashcards

1
Q

MEN stands for?

A

Multiple Endocrine Neoplasia

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2
Q

MEN 1 consists of (3)?

the P adenomas

A

pancreatic islet cell adenomas (produce insulin and gastrin)
pituitary gland adenoma (produce prolactin)
parathyroid hyperplasia or adenoma

aka Werner Syndrome

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3
Q

MEN 2 consists of?

PhAT

A

Phaeochromocytoma
Adenoma (parathyroid)
Thyroid Ca
Also: GIT neuromas, pit tumours, adrenocortical tumours, marfanoid (Type IIB)

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4
Q

MEN 3 consists of?

A

Sipple syndrome

MEN 2 PLUS multiple mucosal neuromas and Marfanoid habitus

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5
Q

APES stands for?

A

Autoimmune Polyendocrine Syndrome

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6
Q

APES 1 consists of? (HAM)

A

APES 1 = childhood
H: hypoparathyroidism
A: Adrenal insufficiency
M: Mucocutaneous candidiasis (T cell dysfunction)

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7
Q

APES 2 consists of ? (DAT)

A 
APES 2 = adult onset
D: T1DM
A: Addison
T: Thyroid (thyroid peroxidase Ab)
Plus: gonadal, skin, Coeliac, Myasthenia
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Endocrinology (8 decks)

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