Mendel Inher Flashcards Preview

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Flashcards in Mendel Inher Deck (10):
1

Autosomal recessive carrier

Has one functional protein and one nonfunctional or missing protein

2

Autosomal recessive affected

- 2 reduced function proteins

3

Sickle cell and cystic fibrosis odds if both parents are carriers

- 1/4 chance of affected/not affected
- 1/2 chance carrier

4

Cystic fibrosis population risk

1/25

5

Autosomal recessive odds if one parent is a carrier

- 1/2 chance carrier
- 1/2 chance non-carrier

6

Autosomal dominant

- No skipping generations
- Equal between males and females
- Huntington's and achondroplasia

7

Autosomal dominant chances if one parent is affected

1/2 chance of affected
1/2 chance of unaffected

8

X-linked inheritance

- Classically only males affected
- Can skip generations
- Unaffected women and affected men can transmit condition
- Haemophilia and Duchenne's muscular dystrophy

9

X-linked. If father is affected and mother is not

- As it is X linked, boys will not get
- Girls will be carriers

10

X-linked. If mother is carrier and father is unaffected

- 50% chance boys will have haemophilia, depends on which X they get from their mum
- 50% chance girls will carry gene