Mendelian genetics Flashcards

(43 cards)

1
Q

Frameshift mutations are what

A

alterations in the reading frame of the

mRNA

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2
Q

We currently have three vaccines in the US

A

2 are RNA vaccines (Pfizer and
oderna)
1 is adenovirus vaccine (Johnson &
Johnson)

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3
Q

Aristotle (300’s BC) proposed that

that particles called pangenes did what

A

came together from all

parts of the body to form the sperm and the egg.

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4
Q

17th century biologists believed that only one of

the parents provided what

A

all of the childs inherited

characteristics

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5
Q

Leeuwenhoek proposed that the sperm contained a

miniature human that he called what

A

a homunculus and the mother

served only as an incubator. spermists

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6
Q

deGraff proposed that the egg contained what

A

the human and

the sperm only served to stimulate growth. ovists

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7
Q

19th century biologists concluded that both

parents contributed to the what

A

e characteristics of the offspring
and that a blending of traits occurred. They called this
the Blending Theory.

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8
Q

BLENDING THEORY proposed what

A

heredity material from each
parent mixed in the offspring and the
characteristics of the offspring would be
intermediate between the parental types

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9
Q

why cant we “see” blending theory

A
We are all
different (exception: identical twins)
-y does not explain
characteristic skip generations to appear in
the next generation
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10
Q

what is PARTICULATE
THEORY OF
HEREDITY (Mendels)

A
Parents transmit to
their offspring
discrete inheritable
factors (traits/genes)
that remain as
separate factors from
one generation to the
next.
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11
Q

why was Mendel successful

A
trained to use math to help explain
natural phenomena
-He chose to
work with garden peas (Pisum sativum)
-e used true breeding varieties
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12
Q

what are true breeding varieties

A

a variety that when it
self-pollinates the offspring are the same as the
parents, generation after generation

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13
Q

exsample of genetic cross

A

1-removed stems from purple flower
2-transfered pollen from stamens of white flower to carpel of purple flower
3-pollinated carpel matired in pod
4-planted seeds from pod
5-examined offspring allpurple flowers (FIRST GEN)

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14
Q

what is p generation

A

true breeding parent (purple and while flower)

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15
Q

what is f 1 generation

A

hybrids (all plants had purple flowers)

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16
Q

what is f2 generation

A

ratio 3:1 (705 plants had purple flowers, 224 plants had white flowers )

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17
Q

what a Gene

A

Discrete unit in the DNA of a chromosome
which carries the hereditary information for a
character/trait

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18
Q

each gene in diploid organism is represented by what

19
Q

what is an allele

A

variant of a gene

20
Q

what is locus

A

Specific location on a

chromosome that contains an allele

21
Q

what is character gene

A
Inheritable feature (e.g. flower
color, eye color, nose shape
22
Q

what is a trait (allele)

A

Variant of character (e.g. purple

flower, blue eyes, pointed nose

23
Q

what is Monohybrid Cross

A
A cross between parental varieties that
differ by one gene
• This type of cross follows the inheritance
of a single gene.
• From this type of cross Mendel deduced
his first law -- the Law of segregation.
24
Q

what is Phenotype

A

organisms observable characteristics

25
what is HOMOZYGOUS:
Having two identical alleles for a given gene
26
what is HETEROZYGOUS
Having two different alleles for a given gene
27
what is the DOMINANT ALLELE:
The allele that is fully expressed in the phenotype on an heterozygous organism
28
what is the RECESSIVE ALLELE:
``` The allele that is completely masked in the phenotype on an heterozygous organism ```
29
what is a PUNNETT SQUARE
Way a predicting the combinations resulting from random genetic crosses
30
Alleles account for what
r the variations in the inherited characters
31
two alleles are | inherited by
one from the mother one from the father.
32
The dominant allele | determines the
appearance of the | organism
33
the recessive allele has
``` no contribution for the appearance of the organism when in presence of the dominant allele ```
34
what is mendels first law
Law of segregation of | alleles:
35
what is the law of segregation of alleles
``` The two allele in a pair of homologous chromosomes segregate (i.e. separate from each other) into different gametes -The alleles then will pair again randomly during the fusion of gametes in fertilization to give rise to the new progeny ```
36
what is a testcrosses
Cross between homozygous recessive and corresponding heterozygote to determine genotype of the latter
37
what is it called when neither allele is dominant
incomplete | dominance
38
What is the genetic basis for | transmission of 2 traits (genes)?
Dihybrid Cross: A cross between parental | varieties that differ by two genes
39
what is the Law of independent | assortment:
``` Each pair of alleles assorts independently in the gametes because the nonhomologous chromosomes assort themselves independently during meiosis I ```
40
when does the law of independent assortment occur
when the genes for two characteristics are located on different pairs of homologous chromosomes.
41
Mendel arrived at two | principles of heredity by doing what.
By following the transmission of well-defined characters from the P generation to the F1 and F2 generations
42
what are two | principles of heredity
1-The law of segregation of alleles | 2-The law of independent assortment
43
the two principles of hereditary show us what
s how the genes are passed on from generation to generation through the same simple rules of chance that apply to the tossing of a coin