Menopause Flashcards

(31 cards)

1
Q

when has a woman reached menopause

A

when she has been amenorrhoeic for 12 months

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2
Q

menopause is a retrospective diagnosis, true or false

A

TRUE

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3
Q

What precedes menopause

A

peri-menopause / climacteric period

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4
Q

What is the average age of menopause

A

51 yr

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5
Q

When is early menopause

A

<45 yr

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6
Q

When is premature menopause

A

<40 yr

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7
Q

When is late menopause

A

> 54 yr

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8
Q

What causes menopause

A

Depletion of ovarian follicles resulting in a decrease in oestrogen levels

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9
Q

What happens to FSH + LH levels as oestrogen decreases

A

They increase (in an attempt to complete negative feedback)

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10
Q

What are the other effects of oestrogen

A
2ndary sexual characteristic development 
hair and fat distribution 
effect on collagen 
helps bone growth 
endometrial proliferation
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11
Q

How is menopause diagnosed normally

A

based on a woman’s clinical symptoms and age

presence of vasomotor symptoms and irregular periods

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12
Q

When are blood tests used in helping diagnosis and at what times should they be taken

A

premature menopause
woman with no uterus / endometrial tissue after hysterectomy
atypical symptoms of menopause
2 blood tests 6 weeks apart

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13
Q

Why are FSH + LH levels not routinely checked

A

because they are released in a pulsatile fashion
they are raised pre ovulation
raised after stopping contraception
single raised levels do NOT confirm menopause

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14
Q

What are the main groups of symptoms a woman experiences in peri-menopause

A

Physical
Psychological
Sexual
Urinary

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15
Q

What are the physical symptoms of menopause

A
hot flushes 
night sweats
palpitations 
insomnia 
joint aches 
headaches
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16
Q

What are the psychological symptoms of menopause

A
mood swings 
irritability 
anxiety 
difficulty concentrating 
forgetfulness
17
Q

What are the sexual symptoms of menopause

A

vaginal dryness

loss of libido

18
Q

What are the later onset of symptoms in menopause

A
urinary frequency 
dysuria 
recurrent UTIs
incontinence
dry hair and skin 
atrophy of breasts and genitals
19
Q

What are the broad management options for menopause

A

Conservative
Menorrhagia Mx
HRT
Non-HRT

20
Q

What are conservative options of management

A
diet
weight loss 
exercise 
reduce caffiene 
CBT 
mindfulness
21
Q

What are options for managing menorrhagia

A
Mefanamic acid - NSAID
Tranexamic acid - antifibrinolytic 
Progestogens 
Mirena IUS 
Endometrial ablation 
Hysterectomy
22
Q

How can HRT be administered

A

PO

transdermal patches

23
Q

Indications for oestrogen only HRT

A

women with no uterus / endometrial tissue (hysterectomy)

24
Q

Indications for combined (oestrogen and progestogen) HRT

A

women with uterus / endometrial tissue present

25
What is a risk of oestrogen only HRT
unopposed oestrogen causes endometrial proliferation and can lead to hyperplasia and endometrial carcinoma
26
Which cancer are you at increased risk of if you take combined HRT
breast cancer
27
What are other risks of taking HRT
VTE PO>transdermal administration | Coronary heart disease and stroke (slight risk)
28
When is monthly cyclical/sequential HRT given
in women who have regular periods going through peri-menopause
29
When is 3 monthly cyclical/sequential HRT given
in women with irregular periods through peri-menopause
30
When is continuous HRT given
Post menopausal women
31
What are non-HRT options for managing menopause
clomidine SSRIs Regelle, Yes, Sylk - vaginal lubricants