Met 1: Pentose Phosphate Pathway

Question 1

What is another name for the pentose phosphate pathway?

Answer 1

Hexose monophosphate shunt (Names based on either starting or end product: takes a 6C phosphorylated sugar and makes a 5C phosphorylated sugar)

Question 2

When does the pentose phosphate pathway occur?

Answer 2

When there is excess glucose present

Question 3

Name 2 products of the pentose phosphate pathway

Answer 3

Ribose-5P and NADPH

Question 4

What is Ribose-5P used for? (4)

Answer 4

synthesis of nucleotides, NADH, FAD, coA

Question 5

What is NADPH used for? (2)

Answer 5

liPid synthesis and fight free radicals

Question 6

How does NADPH fight free radicals?

Answer 6

NADPH needed to make glutathione, which fights free radicals

Question 7

What is the important enzyme is the hexose monophosphate shunt?

Answer 7

Glucose-6-Phosphate Dehydrogenase

Question 8

G6PD deficiency is a _________ (inheritance) disorder that causes _______ when exposed to ______ (food) or _____ (3 drugs)

Answer 8

G6PD deficiency is an x-linked recessive disorder that causes hemolytic anemia when exposed to fava beans sulfa drugs, primaquine, or TB drugs