METABOLIC disorders / 3 Flashcards
What are the 2 types of osteochondrosis
- Scheuermann’s Disease
2. Calve’s Disease
What is osteochondrosis
Interruption of blood supply of epiphysis of bone
What is osteochondrosis of primary center of ossification in the spine
Calve’s disease
What is osteochondrosis of secondary center of ossification on the spine
Scheuermann’s disease
What does Scheuermann’s result in
Kyphotic posture
What ages are effected by Calve’s disease
2-8
How many vertebrae is Calve’s disease limited to
1
What does Calve’s cause
Avascular necrosis of langerhan cells which creates granulomas
What are the types of osteoporosis
Type I and II
What is type I osteoporosis
Postmenopausal osteoporosis
Who gets type I osteoporosis
5-20% of women between 50-70
What is type II osteoporosis
Senile osteoporosis
Who gets type II osteoporosis
Women more than men over 70
What percent of women over the age of 45 will be affected by osteoporosis
30-45%
When does bone mass peak
25-35
How much bone mass loss occurs during the first 5 years of menopause
11%
How much bone mass loss occurs during the following 20 years of menopause
5%
How much calcium do premenopausal women need
Over 1000 mg
How much calcium do postmenopausal women need
Over 1500 mg
What is osteomalacia
Softening of bone without loss of bone matrix
What causes osteomalacia (2)
- Insufficient intestinal calcium
2. Increased renal phosphate losses
What is scurvy
Vitamin C deficiency which leads to failure of osteoblastic formation of bone matrix
What does scurvy cause
Hemorrhagic manifestations and abnormal formation of bones and teeth
What is arthrogryposis multiplex congenita
Nonprogressive neuromuscular syndrome characterized by multiple congenital contractures in and intact skeleton
