Metabolism Podcast - TCA Podcast

Question 1

What does NAD stand for?

Answer 1

Nicotinamide Adenine Dinucleotide.

Question 2

During Glycolysis how much Nicotinamide Adenine Dinucleotide is formed?

Answer 2

2 NADH+ + 2 H+

Question 3

What is the fate of Pyruvate?

Answer 3

Lactic Acid formation

Citric Acid Cycle/ Krebs Cycle

Question 4

What is the enzyme used for anaerobic respiration in humans?

Answer 4

Lactate dehydrogenase

Question 5

Where does the TCA cycle occur?

Answer 5

In the Mitochondria

In the central matrix

Question 6

What occurs in the link reaction between Glycolysis and Krebs cycle/ TCA cycle?

Answer 6

A Pyruvate molecule is converted into Acetyl-CoA via a Pyruvate dehydrogenase complex

• Decarboxylation, CO2 evolved

Question 7

What occurs in the TCA cycle?

Answer 7

Acetyle- Co A(2c) joins with Oxaloacetate molecule (4c)

Form Citric Acid (6c)

Citrate is then decarboxylated twice to give off 2 CO2 molecules

Question 8

What is produced from the TCA cycle?

Answer 8

4 pairs of electrons

3 pairs of electrons accepted by NAD+
1 pair of electrons accepted by FAD
1 GTP produced

Question 9

What are the molecules formed in the Krebs cycle?

Answer 9

Acetyle Co A (2c) + Oxaloacetate (4c)

Citrate 6c

Alpha Ketoglutarate 5c

Succinate (4c)

Fumerate (4c)

Malate (4c)

Oxaloacetate (4c)

Question 10

During anaerobic respiration what is depleted?

Answer 10

NADH depleted

Regeneration of NAD