Metalloproteins Flashcards
What is the primary role of metals in proteins?
Metals serve as essential cofactors that facilitate various biochemical reactions.
True or False: All proteins require metal ions for their function.
False
Fill in the blank: Hemoglobin contains __________, which is a metal that binds oxygen.
iron
Which metal is commonly found in the active site of carbonic anhydrase?
zinc
What type of bond typically forms between metal ions and proteins?
Coordination bonds
Multiple choice: Which of the following metals is NOT typically a cofactor in enzymatic reactions? A) Copper B) Gold C) Magnesium D) Iron
B) Gold
What is the term for proteins that require metal ions for their structural integrity?
Metalloproteins
True or False: Metals can stabilize protein structures by forming ionic bonds.
True
Name two essential metals involved in enzyme catalysis.
Zinc and Iron
Fill in the blank: The metal __________ is crucial for the function of cytochrome c oxidase.
copper
Multiple choice: Which metal is associated with the enzyme superoxide dismutase? A) Calcium B) Manganese C) Mercury D) Sodium
B) Manganese
What is the role of magnesium in DNA polymerase?
It acts as a cofactor that stabilizes the negative charges on the DNA backbone.
True or False: Metals can play a role in electron transfer processes in proteins.
True
What is the effect of metal ion deficiency on protein function?
It can lead to impaired enzymatic activity and protein misfolding.
Fill in the blank: The enzyme alcohol dehydrogenase requires __________ as a cofactor.
zinc
Multiple choice: Which of the following metals is a common cofactor for oxidoreductases? A) Calcium B) Cobalt C) Iron D) Sodium
C) Iron
What is a characteristic feature of metallothioneins?
They are small proteins that bind heavy metals and protect against toxicity.
True or False: All metalloproteins have a structural role and do not participate in catalysis.
False
What is the significance of iron-sulfur clusters in proteins?
They play a crucial role in electron transfer and redox reactions.
Fill in the blank: The metal __________ is often involved in muscle contraction.
calcium
Which metal is associated with the enzyme Glutathione peroxidase?
selenium (Se-)
