Mice

Question 1

What family of mice is considered “house mice”?

Answer 1

Muridae family or Swiss albino mouse

Question 2

Unlike other mammals, what remains active throughout their life?

Answer 2

Marrow of long bone

Question 3

What is barbering?

Answer 3

Chewing off of hair of cagemates

Question 4

What in males is 50% larger than females?

Answer 4

Spleen

Question 5

What is the average life span of a mouse?

Answer 5

12-36 months

Question 6

What is the recommended humidity?

Answer 6

45-55%

Question 7

What is the recommended environmental temp?

Answer 7

24-25 C

Question 8

Mice have __ pairs of mammary glands that extend to sides and back

Answer 8

5 pairs

Question 9

What type of estrus do mice have?

Answer 9

Continuously polyestrus

Question 10

What should be done to females to decrease likelihood of cannibalism?

Answer 10

Leave females undistrubed for 2 days after parturition

Question 11

At what age do females mice develop nipples?

Answer 11

9 days

Question 12

At what age do mice pup ears open?

Answer 12

Day 3

Question 13

At what age do mice pups eyes open?

Answer 13

Day 12-14

Question 14

What is the most common breeding system?

Answer 14

Polygamous (1 male with several females)

Question 15

Until what age are females bred?

Answer 15

9 months

Question 16

What is the term for when large groups of female mice aer housed together without the presence of a male, allowing females to go into anestrus and allows for timed mating

Answer 16

Whitten Effect

Question 17

What is the term for if a pregnant mous is exposed to a new male or its odor within 4 days of breeding. The existing pregnancy will be aborted and the female will return to estrus

Answer 17

Bruce Effect

Question 18

What are some commonly used outbred stocks of mice?

Answer 18

Swiss, swiss Webster, CD 1, CFI SKH1

Question 19

What outbred stock is the hairless breed?

Answer 19

SKH1

Question 20

Most cases of pneumonia are caused by what bacteria?

Answer 20

Mycoplasma pulmonis

Question 21

What bacteria is responsible for Tyzzers disease?

Answer 21

Bacillus piliformis

Question 22

Why is Tyzzers difficult to eradicate?

Answer 22

Resistant spores

Question 23

Bacterial disease that may be fatal in athymic mice or immunocompromised mice

Answer 23

Pasteurellosis

Question 24

Heliobacter bacteria that can cause IBD and hepatic tumors

Answer 24

Hepatitis

Question 25

Treatment for hepatitis includes amoxicillen, metronidazole, and bismuth PO SID X 2 weeks and should never be given via what method?

Answer 25

Never put in water

Question 26

What two bacterial diseases are zoonotic?

Answer 26

Lepto and streptobacillus moniliformis

Question 27

What is the primary agent of viral respiratory disease?

Answer 27

Sendai virus

Question 28

Viral disease uncommon in the US, mouse is the only known host, highly contagious, can be acute, chronic or latent

Answer 28

Mousepox or ectromelia

Question 29

Zoonotic viral disease spread via aersols, bite wounds, transplacental, arthropod vectors. Infected in utero.

Answer 29

Lymphocytic choriomeningitis

Question 30

Corona virus of mice. Enteric strains are most common, altho respiratory strains exist. Treatment not usually attempted

Answer 30

Mouse hepatitis virus

Question 31

Clinical disease only seen in suckling mice, dread fecal oral route, transplacental. Potentially zoonotic. No treatment

Answer 31

Reovirus type 3

Question 32

Acquired through close contact with birds or their feces

Answer 32

Histoplasma capsulatum

Question 33

Rickettsial blood parasite

Answer 33

Eperythrozoon coccoides

Question 34

Most common neoplasia in random bred mice

Answer 34

Pulmonary tumors

Question 35

Trauma in mice housed together, lesions often become infected with what?

Answer 35

S. aureus

Question 36

What are best used to monitor mice under anesthesia?

Answer 36

NM system and RR

Question 37

What makes mice useful for teratology, genetics and gerontology?

Answer 37

High fecundity, short gestation, short life span

Question 38

Susceptibilty to specific viruses and development of certain tumors makes mice useful in what studies?

Answer 38

Virology and oncology

Question 39

Bacterial disease characterized by thickening of intestinal mucosa, mice are most affected species, symptoms include exposive diarrhea and prolapsed rectum.

Answer 39

Transmissible murine colonic hyperplasia ~*citrobacter freundii*

Question 40

What two bacterial diseases are dermatitis?

Answer 40

S. aureus and Streptococcus species

Question 41

How is Sendai virus spread?

Answer 41

Direct contact or aerosol contamination

Question 42

Treatment for mousepox (ectromelia)?

Answer 42

None

Question 43

What serves as the source of infection for mousepox?

Answer 43

Older animals that harbor infection in GI tract

Question 44

Chronic rash and swelling/necrosis of limbs is indicative of what disease?

Answer 44

Mousepox

Question 45

What is the main source of Mousepox (ectromelia)?

Answer 45

Mice/biologics imported

Question 46

How is mouse hepatitis virus transmitted?

Answer 46

Direct contact, oral-nasal, fomites, transplacental

Question 47

True or False Systemic infections in mice are rare

Answer 47

True

Question 48

What is the intermediate host for Moniliformis moniliformis?

Answer 48

Cockroaches

Question 49

Taenia taeniaeformis and Capillaria hepatica are parasites of what organ?

Answer 49

Liver

Question 50

Taenia serialis is a parasite of which organ?

Answer 50

Connective tissue

Question 51

Klossiella muris are parasites of which organ?

Answer 51

Kindeys

Question 52

Hepatozoon muris is parasites within what cells?

Answer 52

Hepatic cells