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Flashcards in Micro Infection drugs Deck (43)
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1

Antibiotics that cause C. Diff

  • Clindamycin
  • Ampicillin, Amoxicillin
  • Cephalosporin
  • Fluoroquinolones 

2

C. Diff 

  • DOC: Oral vancomycin or Fidaxomicin 
  • Metronidazole 

3

Traveler's diarrhea (ETEC)

Ciprofloxacin

4

B. Fragilis intra-abdominal infections

Metronidazole

Carbapenems

Clindamycin

B-lactam + B-lactamase inhibitor 

5

Giardia

Metronidazole 

6

Campylobacter Jejuni

Azithromycin 

7

E. Coli

Cephalosporins, Fluoroquinolones 

8

C. Perfringens

Penicillin +/- Clindamycin 

9

Enterobacter spp

Carbapenem, Cefepime 

10

Enterococcus spp.

Amipicillin +/- Gentamicin

Vancomycin +/- Gentamicin

11

Salmonella Typhi

Ceftriaxone or Fluoroquinolone 

12

S. Aureus or Epidermis 

Methicillin-susceptible 

Nafcillin, Oxacillin, or dicloxacillin (antistaph)

13

S. Aureus or Epidermis 

Methicillin-resistant 

Vancomycin, Linezolid 

14

S. Epidermidis 

Vancomycin

15

GAS pharyngitis

Penicillin V

children? Amoxicillin (tastes better) 

16

GAS with a penicillin allergy

  • type I HSN allergy: azithromycin, clarithromycin, clindamycin
  • non-type I HSN: 1st gen cephalosporin- cephalexin 

17

Bacterial sinusitis/otitis media

Amoxicillin

18

CAP Empirical Treatment:

outpatient, previously healthy
no antimicrobials within last 3 months

  • macrolide (erythromycin, clarithromycin, azithromycin, telithromycin)
  • doxycycline

19

CAP Empirical Treatment:

outpatient - but presence of comorbidities / immunosuppressed/ 
use of IC drugs/ antimicrobials in the last 3 months

or

inpatient, non-ICU

  • respiratory fluoroquinolone (levofloxacin, gemifloxacin, moxifloxacin)
  • B-lactam (cefotaxime, ceftriaxone, ampicillin-sulbactam) + macrolide (TACE -mycin)

20

CAP Empirical Treatment:

inpatient, ICU

B-lactam + azithromycin or respiratory fluoroquinolone

penicillin allergy patients?
respiratory fluoroquinolone (levofloxacin, gemifloxacin, moxifloxacin) + aztreonam 

21

aspiration pneumonia (anaerobes)

DOC: Clindamycin

2. metronidazole 

22

Bordetella pertussis

Macrolide

23

Chlamydia pneuomiae

macrolide or doxcycline

 

24

hemophilus influenzae (otitis media, sinusitis) 
non-b-lactamase producing

Amoxicillin

 

 

25

hemophilus influenzae (otitis media, sinusitis) 
b-lactamase producing

2nd/3rd gen cephalosporin or
amoxicillin-clavulanic acid (child)

26

klebsiella pneumoniae

ceftriaxone, cefotaxime

 

27

Legionella sp.

fluoroquinolones or azithromycin

 

28

moraxella catarrhalis

amoxicillin-clavulonic acid or 
2nd/3rd gen cephalosporins or
co-trimoxazole

 

 

29

mycoplasma pneumoniae

macrolide or doxycycline

 

30

pseudomonas aeruginosa

DOC: Piperacillin or Ciproflaxacin 

2: levofloxacin, aztreonam, aminoglycoside