Micro Lecture 1/2 Flashcards

(44 cards)

1
Q

What are the symptoms of flu

A
  • symptoms quickly develop
  • high fever
  • extreme exhaustion
  • body aches
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2
Q

What animal acts as The melting pot of influenza

A

Pigs

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3
Q

Small mutations/minor changes in vision

A

Genetic drifts

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4
Q

What is the causative agent of SARS

A

Coronavirus

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5
Q

Average amount of colds per year per person

A

1-6 a year per person

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6
Q

What is the mortality rate of bird flu

A

50-70%

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7
Q

What was the strain of Spanish flu

A

H1N1

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8
Q

How is zanamivir (relenza) taken

A

Inhaled

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9
Q

Why was the causative agent of SARS a surprise to virologists

A

Bc coronavirus is just a common cold so they were surprised bc it became lethal

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10
Q

What is the mortality rate of SARS

A

ARDS with 10% mortality

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11
Q

Upper respiratory infection symptoms

A

Rhinitis
Pharyngitis
Tonsillitis
Laryngitis

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12
Q

What are the 2 main neuraminidase inhibitors

A

Zanamivir (relenza) and oseltamivir (tamiflu)

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13
Q

Which strains of influenza are we very concerned with

A

H5N1 and H7

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14
Q

Where to paramyxoviruses replicate

A

Respiratory tract

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15
Q

What patients most affected by adenovirus

A

Infants/children

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16
Q

Facilitates attachment and penetration of virus into host cells

A

Hemagglutinin (H)

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17
Q

What happens if child is givin asprin for viral infection

A

Liver failure and encephalopathy

  • High AST and ALT (liver tests)
  • High PT/INR (clotting proteins)
  • Changes in mental status
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18
Q

What are the symptoms of measles

A
  • High fever
  • conjunctivitis
  • sore throat
  • eyelid swell
  • photophobia
19
Q

Which flu strain is bird flu

20
Q

How effective are neuraminidase inhibitors

21
Q

What are the 2 main causes of acute viral rhinitis

A

Rhinoviruses

Coronaviruses

22
Q

Orthomyxoviruses and paramyxoviruses are what type of virus

23
Q

What sickness is orthomyxovirus

A

Influenza virus (Ordinary flu)

24
Q

How quickly are neuraminidase inhibitors given

A

No later than 48 hrs after symptoms begin

25
Which lasts longer, flu or cold
Flu
26
What are the symptoms of a cold
- No to low grade fever (< 102) - develops gradually - doesn't affect energy level
27
Which type of influenza is only in humans and mild
B and C
28
What is the most common cause of conjunctivitis
Adenovirus
29
What sickness if paramyxovirus
Parade of diseases - parainfluenza virus - mumps virus - measles virus
30
What is reye's syn
Rare and severe complication of viral infections (asprin given to kids)
31
Adenovirus is what type of virus
DNA
32
Mode of transmission of common cold
Hand to hand
33
Assist the virion in entry and budding/escaping from cell
Neuraminidase (N)
34
Why do new strains of influenza often come from pacific rim
Because lots of animals and people are in close proximity
35
Which type of influenza infects multiple animals
A
36
How is oseltamivir (tamiflu) given
PO (oral)
37
What will you see as URI becomes LRI
Fever
38
What strain is the common flu
H1N1
39
What is the toughest respiratory virus
Adenovirus
40
Do you see conjunctivitis in URI
Very rare
41
Abrupt/major reassortments of segments of animal and human H/N spikes that produce new strains
Genetic shifts
42
What should children be given for fever/viral infection
Acetaminophen
43
What are the permissive hosts for flu A
Pigs
44
What are the natural hosts for all flu A viruses
Birds