Microbe Control Flashcards

Understand how microbe growth is controlled by various agents and processes

1
Q

What is the goal of sterilization?

A

The destruction of Bacterial endospores

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2
Q

Which organism is the most resistant?

A

Bacterial Endospores

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3
Q

Which organisms are the least resistant?

A

Enveloped Viruses

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4
Q

Which agents have the widest target range?

A

Heat and Radiation

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5
Q

Agents that are selective in their cellular targets tend to be…

A

more restricted in effectiveness

usually target a single cellular component

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6
Q

How many antimicrobial targets are there?

A

4

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7
Q

What are the targets for antimicrobials?

A
  1. Cell wall
  2. Cell Membrane
  3. Protein
  4. Nucelic Acids
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8
Q

How do antimicrobials interfere with cell walls?

A

Blocking synthesis

Digesting the cell wall

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9
Q

How do antimicrobials interfere with cell membranes?

A

bind to lipid layer, make a hole and disrupt cellular homeostasis

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10
Q

How do antimicrobials interfere with proteins

A

Causes denaturing

Prevents interaction between protein active site and substrate

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11
Q

How do antimicrobials interfere with nucleic acids

A

Acts as a mutagen

Keeps microbes from making proteins

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12
Q

What agents disrupt cell walls?

A

Chemicals
detergents
Alcohols
Surfactants

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13
Q

What agents disrupt cell membranes?

A

Detergents

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14
Q

What agents disrupts proteins?

A

Moist Heat
Alcohol
Phenolics

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15
Q

What agents disrupt nucelic acids?

A

Formalydhyde
Radiation
Ethelyne Oxide

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16
Q

Six (6) methods of physical control

A
Heat
Cold
Desiccation
Radiation
Filtration
Osmotic Pressure
17
Q

What are the types of heat?

Which heat is sterile?

A

Moist heat and Dry heat

Dry Heat

18
Q

Microbe heat resisters are

19
Q

Types of moist heat

A

Boiling
Pasturization
Non-pressure steam
Pressure steam

20
Q

Is cold microstatic or microbial

A

Microstatic

21
Q

Dessication is synonomous with

A

Dessication

22
Q

Radiation types

A

Ionizing radiation

Non-ioninzing Radiation

23
Q

HEPA filters, filter

24
Q

Chemical control agents have _____ action in _______ concentration

A

Rapid; low

25
Chemical control agents must be ______ in water
soluble
26
Chemical control agents must have a ______ microbial range but be ______ to humans
broad; nontoxic
27
Should chemical agents be able to penetrate inanimate objects?
yes
28
Chemical agents should sanitize, deodorize, and be readily available and affordable?
Yes
29
What factors determine germicidal activity
Chemical concentration | Length of exposure
30
What are the levels of chemical decontamination
High- level germicide Intermediate Low
31
What are characteristics of low level germicides
kills vegatative microbes | some viruses
32
What are characteristics of intermediate level germicides
Kills FUNGAL spores kills resistant pathogens kills viruses
33
What is characteristic of high level germicides
killing endospores
34
If a germicide can kill endospores it is assumed that it can kill most other microbes
yes
35
What are the groups of germicidal sterilizers
``` Chlorine Iodine H2O2 Aldehydes gaseous sterilants ```
36
What are groups of germicidal disinfectants
``` Phenol Chlorohexidine Alcohol Detergents Heavy Metal compounds ```