Most common causes of menigitis in children 6 mos - 6 years (3)
1) H. Influenzae
2) N. Meningitis
3. S. Pneumoniae
Gram - Rods: Respiratory Pathogens (3)
1) Bordatella pertussis
2) Haemophilus influenzae
3) Legionella
Gram - Rods: Pathogen acquired from animals (4)
1) Yersinia
2) Pasteurella
3) Brucella
4) Francisella
Gram - Rods: Widespread opportunist
Pseudomonas aeruginosa
Pathogens whose natural habitat is the mucous membrane of the Upper Respiratory Tract (3)
1) H. Influenzae
2) N. Meningitis
3. S. Pneumoniae
Most common causes of meningitis 6-60yrs. (3)
1) N. meningitidis
2) S. pneumoniae
3) Enterovirus
Gram negative Rods: Enterobacteriacae (8)
1) Salmonella - Typhoid and other Enteric Fevers
2) Shigella - Dysentery
3) Yersinia - Bubonic plague
4) Escherchia - Water and Bloody diarrhea (Dysentery), UTI, Septiciemia/meningitis
5) Proteus - UTI
6) Klebsiella
7) Enterobacter
8) Serratia
Most common cause of neonatal meningitis. (3)
1) Group B Strep
2) E. coli
3) Listeria
Most common cause of neonatal pneumonia (2)
1) Group B Strep
2) E. coli
Type III secretion system:
1) S. non-typhoidal
2) S. typhi
3) Y. pestis
4) Shigella
5) EPEC
1) Induce phagocytosis by enterocytes and multiply in phagocytic vesicles. Induce apoptosis of macrophage.
2) Enable survival inside the phagocytic vacuole of macrophages. But do NOT cause apoptosis of macrophage
3) Prevent phagocytosis by neutrophils.
4) Induce phagocytosis of enterocytes at the basolateral surface
5) Transport bacterial protein into enterocyte –> forms a pedistal for itself –> microvilli disappear
