Microbiology Flashcards

(41 cards)

1
Q

The only two gram positive bacteria we need to know

A

Strep Pneumoniae and staph aureus

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2
Q

Discuss the structures of our gram positive bacteria

A

Strep Pneumoniae is a diplococci

Staph Aureus is a cocci in clusters

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3
Q

When do we see strep pneumoniae? What about staph aureus?

A

Strep - Most frequent community aquired and most common in debilitated and elderly.

Staph - Often a complication of influenza, viral pneumoniaes or blood borne infection in IV drug abusers. Also seen in hospitalized patients, the elderly and those with chronic lung diseases.

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4
Q

Presentation of staph aureus vs strep pneumoniae?

A

Bronchopneumonia with staph, strep is lobar and produces rust colored sputum

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5
Q

Complications and treatment for Strep Pneumoniae?

A

Comp - Empyema

Treatment - PCNs, cephalosporins, macrolides, some quinolones

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6
Q

Complications for Staph Aureus and treatment?

A

Comp - Abscess, empyema, bacterial endocarditis

Treat with oxacillin, nafcillin, vancomycin, linezolid

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7
Q

This gram negative coccobacillus requires hematin and NAD+ for culture

A

H Influenza

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8
Q

In whom and in what way does H. Influenza present?

A

Usually infants but we can see it in adults with COPD.

Bronchopneumonia

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9
Q

Complications and treatment for H. Influenza

A

Comp - Meningitis, epliglottitis in infants and kids

Treat with cephalosporins or TMP-SMX

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10
Q

How do we distinguish between Klebsiella and Pseudomonas aeruginosa?

A

They are both gram negative rods!

Klebsiella is more frequent in diabetic or alcoholic patients with a high mortality rate in the elderly.

Pseudomonas appears blue-green when cultured and is a common cause of nosocomial pneumonia and pneumonia in immune compromised and CF patients

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11
Q

Complications of Klebsiella and how we treat it

A

Large amounts of damage to the alveolar walls leading to necrosis and abscess formation..

Treat with aminoglycosides and cephalosporins

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12
Q

Complications of Pseudomonas and how we treat it

A

Focal hemorrhage and necrosis

Treat with combination therapy of cillins and gentamicin

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13
Q

What bacteria requires special charcoal yeast agar with iron and cysteine?

A

Legionella

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14
Q

Legionella has a relatively high mortality rate if left untreated. How do we treat it?

A

Macrolides and quinolones

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15
Q

What bacteria produces red currant-jelly sputum? What type of PNA do we see with this bacteria?

A

Klebsiella and we typically see a bronchopneumonia

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16
Q

Discuss the characteristics of moraxella catarrhalis and who we see it in

A

This is a gram negative diplococci seen in the elderly and patients with COPD.

It constitutes a bronchopneumonia

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17
Q

How do we treat M. Catarrhalis?

A

Cephalosporins, macrolides, quinolones

18
Q

Aspiration pneumoniae usually contains these bacteria and we treat them this way:

A

Bacteria that are native to you! Treatment is just PCN and clindamycin

19
Q

Mycoplasma pneumoniae is our young adult pneumonia. As a review, what kind of PNA does it cause and what is it associated with it.

A

Interstitial and is associated with nonspecific cold agglutinins

20
Q

This bacteria is found in parrot feces and causes a certain condition

A

C. Psittaci and it causes psittacosis

21
Q

Chlamydophila pneumoniae is a ___ bacteria that targets ____ and causes ____ PNA.

A

Obligate intracellular
Columnar epithelium
Interstitial

22
Q

We treat Chlamydophila with this (in your answer provide an example of each)

A

Macrolides like erythromycin

Tetracyclines like Doxycycline

23
Q

Complications of Coxiella and how we treat it

A

Can cause hepatitis or myocarditis.

We treat with Doxycycline

24
Q

We have a bunch of viral pneumonias that can get kids. Which ones can we treat and how?

A

Influenza A:: Amantadine and rimantadine
Influenza A and B: Zanamavir and oseltamivir
RSV (Prophylactically): Palivizumab and ribavirin

25
This is an AIDs defining classic sign
Ground glass opacitis on CT, associated with Pneumocystis jirovecci. We can also see on silver stain alveolar cysts
26
How do we treat AIDS bacteria?
TMP-SMX: Always give prophylactically if CD4+ count is less than 200
27
What yeasts do we need to be aware of
Candida Albicans | Cryptococcus neoformans
28
How do the two yeasts we need to know present?
Candida Albicans - Fever, tachypnea, patchy infiltrates on chest film Cryptococcus Neoformans - Often asymptomatic, but can have productive cough, fever, and weight loss
29
Discuss who we tend to get candida albicans in and how we deal with it
This is a very uncommon cause of PNA, however in immune-compromised patients this can present in a hematogenous spread. We treat with Amphotericin B and fluconazole
30
Cryptococcus neoformans is associated with this finding and can lead to this.
Associated with pigeon poop and can lead to cryptococcal meningitis.
31
Cryptococcus neoformans treatment
Cryptococcal meningitis - Give amphotericin B with Flucytosine If it is non-CNS cryptococcis, give Fluconazole
32
Narrow angle branching hyphae = what and how do we treat
Aspergillus. Treat with amphotericin B or itraconazole
33
Asperigillus is a ____
mold
34
Blastomycoses, coccidiodomycoces and histoplasmosis are all what?
Dimorphic fungi
35
Blastomycoses and coccidiomycoces presentation
Present with constitutional symptoms. Blasto - Skin lesions, bone lesions, GU involvement Coccidio - CP, HA
36
Our dimorphics present in different locations.Where are they?
Blasto - Midwest and Southeast U.S. Coccidio - Southwest U.S., Mexico, South America Histoplasmosis - River valleys of central U.S.
37
Cellularity of Blasto
Budding yeast inhaled from soil that causes PNA like lung disease.
38
Cellularity of histoplasmosis
Round/oval yeast from soil contaminated by bat and bird shit. Elicits caseating granuloma formation in tissue. Can cause multisystem issues with infiltrating macrophages filled with intracellular fungi.
39
Ceullarity of Coccidio
Fungal spherules containing endospores are found within granulomas.
40
Treatment for our dimorphic yeasts
Blasto - Ampho B or itraconazole Histo - Ampho B with or without itraconazole Coccidio - Ampho B and/or surgery
41
Appearance and testing for cryptococcus
Organism's encapsulated appearence can be seen with India ink stain and latex agglutination test