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*Unit 6 ER > Microbiology > Flashcards

Flashcards in Microbiology Deck (60):
1

Lactose fermenters turn _____ on MacConkey agar

Pink

2

What are the only 2 lactose fermenting bacteria?

1. Klebsiella pneumonia
2. E. coli

3

What are the 3 bacterial that cause HUS?

1. Shigella
2. E. coli
3. campylobacter

4

This is a non-spore forming, gram (+) rod often transmitted by dairy products

Listeria monocytogenes

5

How does shigella invade the body?

fecal-oral, invades though M-cells

6

Aside from chlamydia, what Enterobacteriaceae can cause reactive arthritis?

1. Shigella
2. Salmonella
3. Yersinia
4. Campylobacter

7

What two Enterobacteriaceae can carry the "shiga toxin"?

1. Shigella
2. E. coli

8

Shigella, Salmonella and Yersinia carry a type ___ secretion system

type III

9

How does Shigella cross from the invaded M cell to neighboring epithelial cells?

uses host M cell's actin filaments for propulsion

10

What virulence factor is the trigger for HUS?

the SHIGA toxin

11

Which Enterobacteriaceae can cause neutrophiles in the stool?

1. Shigella
2. Salmonella
3. Campylobacter

12

Use antibiotics for infection with (shigella/E coli)

Shigella only, Abx with E. coli can precipitate HUS

13

Which turns black on Hektoen agar? why? (E. coli/ Salmonella/Shigella/Yersinia)

salmonella, is H2S positive

14

What is the Infectious dose for salmonella? Shigella?

Salmonella, 100,000, is acid labile
shigella, 100, is acid stable

15

Which invade macrophages? (E. coli/ Salmonella/Shigella/Yersinia)

salmonella
(to some extent shigella)

16

Which is acid-labile? Acid stable? (shigella/salmonella)

Shigella is acid stable: survives stomach acid
Salmonella is acid labile: stomach acid kills, need a high infectious dose

17

What causes typhoid fever?

Salmonella typhi

18

What organ does Salmonella form a chronic carriage?

the Gallbladder

19

Heterozygosity for the _______ allele confers protection against typhoid fever

CTFR, cystic fibrosis

20

Rose spots appear on the stomach with (E. coli/ Salmonella/Shigella/Yersinia)

salmonella
rose spotted bib

21

Salmonella + Sickle cell anemia --> _________

Osteomyelitis

22

Which causes "false appendicitis"? (E. coli/ Salmonella/Shigella/Yersinia)

Yersinia enterocolitica, painful swollen lymph node

23

How can you identify listeria under the microscope?

'Tumbling Motility' is characteristic

24

Why might pregnant women be advised to avoid soft cheeses?

Risk of Listeria infection

25

How do you treat a listeria infection?

Ampicillin (can add gentamicin for week 1)

26

Which enteric agent makes 'actin rockets' to propel through multiple cells?

Listeria
(Shigella uses IcsA to polymerize actin filaments for propulsion as well)

27

What enteric agent can escape the GI and proliferate in the placenta and attack the fetus?

Listeria

28

Vaginal transmission of Listeria during birth can cause ________

neonatal meningitis

29

Which has LPS? (gram +/ gram -) bacteria

Gram (-)

30

Is listeria gram + or - ?

Gram +, purple

31

What should you put in the IV of someone with severe cholera infection?

Lactated ringer solution

32

Which causes rice water diarrhea? what about the others? (V. cholera/ V. parahaemolyticus/ V. vulnificus)

Severe rice water diarrhea: V. cholera
Various diarrhea: V. parahaemolyticus
Rarely known for diarrhea: V. vulnificus

33

which is known for shellfish contaminated wounds? (V. cholera/ V. parahaemolyticus/ V. vulnificus)

shellfish wounds: V. vulnificus

34

At what temp does campylobacter grow? what is a chicken's body temperature?

campy grows at 42C, same as a chicken

35

what lab breath test can be done for Helicobacter pylori?

urea breath test, H. pylori is urease (+)

36

What bacteria species is ass. with eating undercooked seafood? how do you expect it to gram stain?

V. cholera and V. parahaemolyticus are gram - rods

37

what is the leading cause of severe diarrhea in infants and children?

rotavirus

38

How long the diarrhea last with rotovirus? norovirus?

rotavirus: 5 days
norovirus 2 days

39

What are the 3 presentations of Coxsackie A virus?

1. herpangina
2. hand and mouth
3. acute hemorrhagic conjunctivitis

40

What is the presentation of Coxsackie B virus?

1. Dilated cardiomyopathy
2. pleurodynia

41

What is the cause of "beaver fever"

giardia, infects mammals

42

What are the symptoms of giardia infection?

flatus, weight loss, diarrhea greasy stool w/ odor, floating stool

43

What is the most likely outcome of a giardia infection? What is the Rx?

clearance in 60% of cases
Rx: tinidazole, like metronidazole

44

Contaminate water supply from cow/calf run-off, causes diarhea 10-14 days then resolves, can be sever in AIDS/immunocompromised

Crytosporidium parvum

45

How do you prevent Crytosporidium parvum? How do you treat it?

Prevent by water filtration
Treat by Nitazoxanide (or spiramycin)

46

Which parasite penetrates the mucosa of the colon and can make hepatic and renal cysts?

Entamoeba histolytica

47

What is the treatment for Entamoeba histolytica?

Metronidazol (paramycin and iodoquinol to eliminate cysts)

48

From what meat can you get:
taenia solium
taenia saginata
diphyllobothrium latum

taenia solium: pork
taenia saginata: beef
diphyllobothrium latum: fish

49

Which can cause brain and muscle lesions:
taenia solium
taenia saginata
diphyllobothrium latum

taenia solium: pork

50

Which can cause B12 deficiency and pernicious anemia
taenia solium
taenia saginata
diphyllobothrium latum

diphyllobothrium latum: fish

51

What are the S+S of Ascaris lumbricoides?

pulmonary symptoms, eosinophilic pneumonia, intestinal obstruction

52

Which can cause perianal pruritus? (Ascaris lumbricoides/ Strongyloides stercoralis/ Enterobius vermicularis)

Enterobius vermicularis

53

Which can be Dx with adhesive tape? (Ascaris lumbricoides/ Strongyloides stercoralis/ Enterobius vermicularis)

Enterobius vermicularis

54

Which can cause fluctuating eosinophilia with maculopapular rash on the buttock, perineum and thighs
(Ascaris lumbricoides/ Strongyloides stercoralis/ Enterobius vermicularis)

Strongyloides stercoralis

55

Which is also called "pin worm"
(Ascaris lumbricoides/ Strongyloides stercoralis/ Enterobius vermicularis)

Enterobius vermicularis

56

Nemetodes, Tremetodes and Cestodes are all ________

helminths

57

Ascaris lumbricoides, Strongyloides stercoralis, Enterobius vermicularis are all (Cestodes/ Nematodes/ Tremetodes)

Nematodes

58

T. solium T. saginata and D. Latum are all (Cestodes/ Nematodes/ Tremetodes)

Cestodes

59

What family of virus is hep C? RNA or DNA?

flavi virus, RNA genome

60

What is the MC cause of erysipelas?

S. pyogenes