Flashcards in Microbiology Deck (59)
What organisms are typically involved in a prosthetic joint infection?
Coagulase negative Staph
What organisms typically cause septic arthritis?
What organisms tend to be responsible for post-traumativ infections?
What bacteria are often involved in vertebral osteomyelitis?
What organisms typically cause diabetic foot infections?
What bacteria is a less common infective organism but is more common in kids under 5 years old?
A 3 year old child presents with pain in his right hip. his mother says he hasn't been feeding very well. On examination his temperature is 39.1, and there is obvious swelling and erythema over his right hip. Any attempt to touch or move the hip is met with obvious pain.
Acute bone and joint infection
How do we classify Systemic Inflammatory Response Syndrome (SIRS)?
Two or more of:
- Temperature >38 or 20 or PaCO2 12,000 cells/mm^3 OR 90
What are some rarer causes of septic arthritis?
When would a blood culture be carried out?
If the patient is pyrexial
What is the empiric treatment for septic arthritis in:
1. High dose flucloxacillin
2. High dose flucloxacillin and ceftriaxone
How long does septic arthritis treatment continue?
What is osteomyelitis?
Inflammation of bone and medullary cavity
Where does osteomyelitis tend to occur?
What are acute causes of osteomyelitis?
What bacteria may cause chronic osteomyelitis?
How long does acute osteomyelitis last?
Few days to
How might osteomyelitis spread into the joint space?
Since metaphysis is intracapsular in these joints:
Why are infants at an increased risk of septic arthritis after osteomyelitis?
Vessels cross into epiphysis
What processes occur that may lead to chronic osteomyelitis?
2. Permanent damage
Why is there not an immediate need for antibiotics in chronic osteomyelitis?
SIRS is usually absent
When would we start antibiotics in chronic osteomyelitis?
Once we achieve culture results
What is the empiric treatment for osteomyelitis?
High dose flucloxacillin:
- Modify after culture
- 4 to 8 weeks
Which of the following is not a risk factor for a prosthetic joint infection:
What are the three types of implant infection?
Early postoperative (0-3 months)
Delayed (Low grade) (3-24 months)
Late (> 24 months)
A patient presents with persistent pain in her left hip. She had a hip replacement 18 months ago. She is a diabetic and has a BMI of 32.
What features of CoNS make them difficult to treat?
Produce a biofilm over prosthesis
What cultures may aid in the diagnosis of a PJI?
Tissue and bone (multiple)
How do we treat a PJI?
Remove prosthesis and cement
Treat with antibiotics
Wait > 6 weeks until joint is re-implanted