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Flashcards in microbiologyss_20200626142001 Deck (424)
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1

Nomal cell mediated; Low levels of all immunoglobulins; tyrosine kinase deficiency

x-Linked agammaglobulinemia/Bruton's Agammaglobulinemia

2

6 mos male infant; recurrent pyogenic and enteroviral infections; recurrent giardiasis

x-Linked agammaglobulinemia/Bruton's Agammaglobulinemia

3

Failure of isotype switching; do not give gamma globulin

Selective IgA deficiency

4

Defect in B-cell maturation to plasma cells; Most common form of severe antibody deficiency affecting both children and adults

Common Variable Immunodeficiency

5

CATCH 22 = DiGeorge Syndrome

Cardiac Anomalies (TOF); Abnormal Fascies; Thymic aplasia; Cleft Palate; Hypocalcemia; 22q11.2 Chromosomal Deletion

6

specific T-cell defeciency for Candida Albicans

Chronic Mucocutaneous Candidiasis

7

X-linked defect in IL-2 receptors in T-cells

SCID

8

autosomal Adenosine deaminase deficiency

SCID

9

Inability to mount IgM response

Wiskott-Aldrich Syndrome

10

WASP Gene Mutation (how do you TIE a WASP?)

Thrombocytopenia, Infections, Eczema, WASP Mutation)

11

ATI of Ataxia-Telangiectasia

Ataxia, Telangectasia, IgA deficiency

12

Lack of NADPH Oxidase activity; Failure of oxidative burst

Chronic Granulomatous Disease

13

Diagnostic Test for Chronic Granulomatous Disease

Nitroblue Tetrazolium

14

Autosomal recessive; failure of phaglysosomal fusion presenting as recurrent pyogenic infections caused by staph and strep

Chediak-Higashi Syndrome

15

Mutation in integrins; defective adhesion (LFA-1) proteins on the surface phagocytes

Leukocyte Adhesion Deficiency

16

Most common complement defect

C2 deficiency

17

c5-c9 deficiency

Terminal complement deficiency

18

Egg Yolk Agar

Clostridium perfringens

19

Tellurite

Corynebacterium diphtheriae

20

Bile Esculin

Group D Streptococci

21

Mannitol Salts

Staphylococci

22

Chocolate Agar

Neisseria from Sterile Sites (N. meningitidis & N, gonorrhoeae)

23

Thayer Martin

Neisseria from nonsterile sites

24

Chocolate agar + Factors 5 and 10

Haemophilus influenzae

25

Lowenstein Jenses/Middlebrook

Mycobacterium tberculosis

26

Thiosulfate Citrate Bile Salts (TBCS)

Vibrio cholerae

27

Bordet-Gengou/Regan-Lowe

Bordetella pertussis

28

Charcoal-yeast extract ( iron+cysteine)

Legionella pneumophila

29

Skirrows

Campylobacter, Helicobacter

30

Barbour-Stoenner-Kelly (BSK)

Borrelia burgdorferi