Microscopic Structure Of BV Flashcards

(67 cards)

1
Q

Large elastic arteries leave the

heart and branch to form

A

muscular arteries.

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2
Q

muscular arteries branch further
and enter—— , where they
branch much further to form

A

organs

arterioles

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3
Q

arterioles branch into the

smallest vessels, the———

A

capillaries

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4
Q

capillaries are

A

the site of exchange between
blood and surrounding tissue.

smallest vessels

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5
Q

Capillaries then merge to form

A

venules

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6
Q

Venules merge further into—-
and then———sized
veins.

A

small

medium

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7
Q

small
and then medium vein leave organs, form
————which eventually
bring blood——

A

larger veins

back to the heart.

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8
Q

In the basic structure of any vessel there are three layers:

A

1) tunica intima (the inner layer)
2) tunica media
3) tunica adventitia /externa (The Outer layer)

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9
Q

tunica intima

A

the inner layer: Endothelial cells and sub-endothelial connective tissue

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10
Q

tunica media

A

elastic fibers and smooth muscles (thicker than intima )

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11
Q

tunica adventitia /externa

A

The Outer layer: A connective tissue layer , continues with the connective tissues surrounding the blood vessel.

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12
Q

Mention large elastic arteries?

A

the ascending / arch / descending aorta

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13
Q

large size arteries ,and because of the ———they are also called elastic arteries

A

large amount of elastic fibers

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14
Q

muscular arteries.

the tunica media of these arteries have

A

large amounts of smooth

muscles

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15
Q

muscular arteries further divided into arterioles , which have a

A

very thin tunica media

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16
Q

The capillaries is only an

A

endothelium supported by a basement membrane , no other layers

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17
Q

small and then medium—sized veins (Have—- amount of muscles in Tunica media )

A

Less

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18
Q

The most important feature in Large size veins (e.g. IVC) is the presence of

A

smooth muscle fibers in tunica externa (only in this type of veins)

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19
Q

Walls of both arteries and veins have a—————,

A

tunica intima, tunica media, and tunica externa (or adventitia)

endoca

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20
Q

artery has a thicker ——and relatively narrow——-.

A

tunica media

lumen

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21
Q

vein has a larger——— and its——- is the thickest layer.

A

lumen

tunica externa

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22
Q

The tunica intima of veins is often folded to form

A

valves.

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23
Q

True or false

Capillaries have only an endothelium, with no subendothelial layer or other tunics.

A

T

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24
Q

line the tunica intima

A

Simple squamous endothelial cells

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25
tunica intima has
-endothelial cells -subendothelial loose connective tissue
26
tunica intima is separated from the tunica media by
internal elastic lamina (IEL)
27
internal elastic lamina (IEL)
prominent sheet of elastin.
28
The media (M) contains
elastic lamellae and fibers (EF) and multiple layers of smooth muscle
29
The tunica media is—— in large arteries than veins, with relatively more elastin.
thicker
30
Elastic fibers are also present in the tunica adventitia (A), which is relatively —-in large veins.
thicker
31
Vasa vasorum (V) are seen in
adventitia of the aorta.
32
The connective tissue of the adventitia always merges with the
less dense connective tissue around it.
33
large elastic arteries tunica media consists mainly
elastic fibers
34
if muscular arteries tunica media consists mainly
Smooth muscles fibers
35
larger vessels, as the
aorta
36
Walls of the larger vessels contain in the tunica adventitia a
supply of microvasculature to bring O2 and nutrients to local cells too far from the lumen to be nourished by blood there. -small sympathetic nerves (N) for control of vasoconstriction.
37
constitute the vasa vasorum (vessels of | vessels).
arterioles (A), capillaries and venules (V)
38
The largest arteries contain
1-considerable elastic material and expand with blood when the heart contracts. 2-thick tunica media (M) consisting largely of many well developed elastic lamellae.
39
Strong pressure of blood pulsating into such arteries during systole
expands the arterial wall, | reducing the pressure and allowing strong blood flow to continue during diastole.
40
intima (I) of the empty aorta is typically—— and the adventitia (A) contains
folded vasa vasorum.
41
``` medium sized artery shows a—— tunica media (M) consisting largely—— ```
thick | smooth muscle fibers.
42
Why so large sized arteries need elastic | the fibers ?
?
43
Microvasculature arises to?
nutritional | needs of one organ or parts of one organ
44
Microvasculature consists of blood vessels of
less than 0.5 mm | diameter.
45
Microvessels include
arterioles metarterioles( arterioles smaller branches)
46
Microvessels include arterioles and their smaller branches called metarterioles in which the layer of smooth muscle cells is dispersed as bands of cells that act as?
precapillary sphincters.
47
The distal portion of the metarteriole, sometimes | called a ——— and it lacks—-
thoroughfare channel, any smooth muscles muscle cells.
48
The wall of capillaries lacks
smooth muscle cells | altogether.
49
The precapillary sphincters allow blood to enter the ——in a ——manner for maximally efficient exchange of nutrients, wastes, O2, and CO2 across the capillary wall.
the bed of capillaries pulsatile
50
Capillaries and the metarteriole converge as ——-, the last component of the microvasculature. Blood enters microvasculature well—oxygenated and leaves poorly oxygenated.
postcapillary venules
51
——-make up the microvasculature where in almost every organ, exchange takes place between blood and the interstitial fluid of the tissues.
Arterioles (A), small capillaries (C) and venules (V)
52
Arterioles are microvessels with a tunica intima (I) that consists only of the ——- in which the cells may have——
endothelium rounded nuclei.
53
Arterioles have tunica media (M) with only———-, and usually——, inconspicuous adventitia (Ad).
one or two layers of smooth muscle thin
54
Capillaries consist only of an endothelium rolled as a tube, across which molecular exchange occurs between blood and tissue fluid.
T
55
Capillaries are normally associated with perivascular contractile cells called ——which have a variety of functions. The more—— nuclei belong to endothelial cells.
pericytes (P) flattened
56
Capillary—- wall of one endothelial cell covered by an external lamina (arrows). Endothelial cells have numerous—— vesicles and their edges overlap and are bound tightly together with——-
thin transcytotic vesicles occluding junctions (J).
57
Pericytes can proliferate to form ——-when a capillary is transformed into an——
smooth muscle cells arteriole or venule after tissue injury and repair.
58
Types of capillaries
(a) : Continuous capillaries, (b) : Fenestrated capillaries (c) : Sinusoids
59
Continuous capillaries, the most common type, have?
tight, occluding junctions sealing the intercellular clefts between all the endothelial cells to produce minimal fluid leakage
60
Continuous capillaries, | All molecules exchanged across the endothelium must cross the cells by
diffusion or transcytosis.
61
Fenestrated capillaries have——-, but perforations (fenestrae) through the endothelial cells——
tight junctions allow greater exchange across the endothelium.
62
Fenestrated capillaries, external lamina is
continuous in both a and b
63
Fenestrated capillaries are found in organs where molecular exchange with the blood is important, such as
1) endocrine organs, 2) intestinal walls, and 3) choroid plexus.
64
Sinusoids usually have a
1) wider diameter 2) discontinuities between the endothelial cells, large fenestrae through the cells, 3) partial, discontinuous basement membrane.
65
Sinusoids are found in organs where ———and cells occurs readily between tissue and blood, such as in
exchange of macromolecules bone marrow, liver, and spleen.
66
Continuous capillary
tight or occluding junctions | Numerous transcytotic vesicles are evident (small arrows).
67
Fenestrated capillaries are specialized for uptake of molecules such as——— or for outflow of molecules such as in the—-
hormones in endocrine glands kidney’s filtration system.