Midterm 1 Flashcards
(23 cards)
What snips off the arginine and leusine in polypeptide biosynthesis?
A carbonyl peptidase H
What cells are in the a cells category of anterior pituitary
Lactotrope and somatotrope
What is the name of the cells of the B cells anterior pituitary
Gonadotropes and thyrotropes
What is the name of the cell that is chromophobe in anterior pituitary
Corticotrope
What are the three gene families and what cells do they correspond to?
A- GH and PL, B- FSH/LH/TSH, C- ACTH
What hormones come from magnocellular?
Vasopressin or oxytocin
Which originate from parvocellular?
Releasing factors
What hormone is from the somatotrope?
Growth hormone
Which hormone inhibits prolactin?
Dopamine
Which type of cell is responsible for prolactin?
Lactotrope
Which hormone is released from the hypothalamus into the anterior pituitary in gonadotrope?
GnRH
What hormones are released by the gonadotrope?
LH and FSH
Which hormone is released by corticotrope?
ACTH
What turns on ACTH release?
CRH
What turns off ACTH release?
AVP
What does phosphodiesterase do in the cAMP/PKA pathway?
It breaks down cAMP
What does phospholipids C do for the IP3/DAG pathway?
Breaks down IP3/DAG
What does IP3 do?
Bonds to calcium channel to release it
What does calcium do in IP3/DAG do?
Binds to calmodulin and PKC to cause an effect through phosphorylation
What does DAG do?
Activates PKC
What takes the tyrosine receptors to be degraded?
Ubiquitin
Which is the insulin pathway?
Tyrosine kinase 2
What does thyroid bind to and what comes off in mode of action?
Thyroid receptor, inhibitor comes off + goes on
