MIDTERM MINOR BLOOD GROUP

Question 1

Diego system ISBT number

Answer 1

010

Question 2

The Diego system is composed of how many antigens

Answer 2

22

Question 3

Diego antigens SLC4A1 is located at chromosome

Answer 3

17q21-q22

Question 4

Location of Diego Blood group

Answer 4

anion exchange protein (AE-1) aka
erythrocyte band 3

Question 5

The Dia/Dib polymorphism is located on

Answer 5

last (seventh) extracellular loop of the
protein

Question 6

Mutation in AE-1 results to what conditions

Answer 6

Hereditary Spherocytosis, Congenital Acanthocytosis, and Southeast Asian Ovalocytosis

Question 7

Diego system are what class of antibodies

Answer 7

Sometimes IgM but usually IgG

Question 8

Band 3 is also known as

Answer 8

Red cell ion exchanger

Question 9

Phenotype of GPA-deficient RBCs in Diego system

Answer 9

Wr(a-b-)

Question 11

ISBT number of Yt system

Answer 11

011

Question 12

The Yt blood group system was named after

Answer 12

Cartwright

Question 13

Where is the Yt antigen located

Answer 13

Chromosomes 7q22

Question 14

Yt antibodies are what class antibodies

Answer 14

IgG

Question 15

ISBT number of Xg system

Answer 15

012

Question 16

Xg is more common in

Answer 16

Females

Question 17

Two antigens of Xg system

Answer 17

Xga and CD99

Question 18

CD99 is also known as

Answer 18

12E7 and MIC2

Question 19

Xga is located at

Answer 19

Chromosome Xp22.3

Question 20

Gene responsible for CD99 is located at

Answer 20

Xp22.2

Question 21

Anti-Xga antibodies are what class of antibodies

Answer 21

IgG

Question 22

The scianna system ISBT number

Answer 22

013

Question 23

Antigens of scianna system

Answer 23

Sc1 and Sc2

Question 24

SC gene is located at

Answer 24

Chromosome 1p34

Question 25

Product of Sc gene

Answer 25

Erythroid membrane-associated protein

Question 26

Scianna antibodies are what class of antibodies

Answer 26

IgG

Question 27

Dombrock System ISBT number

Answer 27

014

Question 28

The dombrock system was named after

Answer 28

Mrs. Dombrock

Question 29

The gene encoding the dumbrock glycoprotein is located on

Answer 29

Chromosome 12p12.3

Question 30

The dombrock antigens are carried on _______ attached to the rbc membrane

Answer 30

Mono-ADP-ribosyltransferase 4

Question 31

The colton system ISBT number

Answer 31

015

Question 32

The colton system was named after

Answer 32

Calton

Question 33

Antigens of colton system

Answer 33

Coa, Cob, Co3, Co4

Question 34

The colton antigen are carried on what protein

Answer 34

aquaporin 1

Question 35

The gene AQP1 is located at

Answer 35

Chromosome 7p14

Question 36

The Landsteiner-Wiener system ISBT number

Answer 36

016

Question 37

Three LW antigens

Answer 37

LWa, LWab, LWb

Question 38

The LW glycoprotein is part of

Answer 38

Band 3/Rh macrocomplex

Question 39

LW gene is located on

Answer 39

Chromosome 19p13.3

Question 40

Structure that carries the LW antigens

Answer 40

ICAM-4

Question 41

The chido/Rodgers system ISBT number

Answer 41

017

Question 42

Anti-Ch and Anti-Rg can be neutralized by

Answer 42

Plasma

Question 43

Give the two isoforms of C4 glycoprotein and the antigen it carries

Answer 43

C4B: Ch antigens C4A: Rg antigens

Question 44

Ch and Rg genes are located at

Answer 44

Chromosome 6p21.3