Midterm Terms Flashcards

(48 cards)

1
Q

Ganglia

A

Concentration of cell bodies

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2
Q

What do dendrites do?

A

Receive messages from other cells

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3
Q

What do Axon do?

A

passes messages away from the cell body to other neurons, muscle or glands

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4
Q

what does the myelin sheath do?

A

Covers axon of some neurons & helps to speed neural impulses

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5
Q

What are bipolar neurons?

A

In special sense organs b/w receptors & other neurons
Has 2 proceses (dentritic & axon)

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6
Q

What are unipolar neurons?

A

Fused dendrite & axon
Most sensory neurons are unipolar

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7
Q

What are multipolar neurons?

A

2 or more dendrites & single axon
Most common neurons in CNS & all motor neurons controlling skeletal muscles

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8
Q

What do Oligodenrocytes do?

A

Located in CNS
Create myelin

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9
Q

What do Ependymal cells do?

A

Located in CNA
Lines internal cavities of brain & spinal cord
Produce & circulate CSF

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10
Q

What do microglia cells do?

A

Located in CNS
Macrophages, that phagocytize dead tissue, debris & pathogens
Concentrated at sites of trauma & injury
Carry out immune responses in CNS

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11
Q

What do astrocytes do?

A

In CNS
Cover brain surface, provide framework for tissue
Contact capillaries to form blood-brain barrier
Regulate blood flow & composition of tissue fluid

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12
Q

What do Schwann cells do?

A

Located in PNS
Create myelin

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13
Q

What do satellite cells do?

A

Located in PNS
Insulate somas in ganglia of PNS

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14
Q

During the action potential, what happens when voltage gated K+ channel open?

A

K+ leaves the cell & membrane hyperpolarizes

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15
Q

At what location on a neuron does an action potential initiate?

A

Axon Hillock

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16
Q

What role does myelin play in controlling neuronal signaling>

A

Enhances speed of electrical signals along an axon

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17
Q

How is threshold reached?

A

Na+ enters a cell until voltage reaches -50mV

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18
Q

During an action potential, voltage gated Na+ channels are responsible for which voltage shift?

A

-50 mV to +35mV

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19
Q

A neuron is in the relative refacroty period when making which voltage shift?

A

-73mV to -68mV

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20
Q

During action potential, voltage gated K+ channels are responsible for which voltage shift?

A

+35mV to -73mV

21
Q

After threshold is reached, which ion channels open first?

A

Na+ channels, which let Na+ into the cell

22
Q

Which ion enters a neuron following glutamate binding to its receptor?

A

Na+, which depolarizes the neuron

23
Q

Which channels are responsible for producing local potentials?

A

Neurotransmitter-gated channels along dendrites

24
Q

Describe AMPA receptors

A

ionotrophic
Na
excitatory

25
Describe DR 1&5
Metabotrophic activates kinases that phosphorylate AMPA/NMDA (excitatory) Phosphorylates CREB for plasticity
26
Describe DR 2,3,4
Metabotrophic Inhibits kinases that phosphorylate AMPA/NMDA (Inhibitory) Prevents Phosphorylates of CREB for plasticity
27
GABA A
Ionotrophic Cl- Inhibitory
28
Describe GABA B
Metabotrophic Activate Girk channel, inhibit Ca2+ channels Inhibitory
29
Ionotropic 5HT3 receptor
Serotonin receptor Na excitatory
30
mACHR
Musacrinic Ach receptors Metabotropic Activate GIRK channel, inhibit Ca2+ channels inhibitatory
31
Metabotropic 5HT3 receptor
Metabotropic Either activate/deactivate protein kinases, protein kinase then activate GIRK channel inhibitory
32
mGLUR 1 & 5
Metabotropic Activates kinases that phosphorylate AMPA/NMDA excitatory Phorphorylates CREB for plasticity
33
mGLUR 2 & 3
Metabotropic activation of GIRK channels inhibitory
34
nAchR
Ionotropic Na excitatory
35
NMDA
Ionotropic Na & Ca excitatory
36
GlyR
Ionotropic Cl- inhibitory
37
What portion of neuron releases neurotransmitter?
Axon terminal
38
In which region of a neuron are most of its organelles, such as nucleus located?
Cell Body
39
What is a reuptake transporter?
Pre-synaptic protein that allows neurotransmitters back into an axon terminal
40
What is a ligand-gated ion channel?
Post synaptic receptor that directly generates electrical current
41
What is a G-Protein coupled receptor
Post synaptic receptor that generates second messengers
42
When an action potential reaches an axon terminal what generates electrical current?
Voltage gated calcium channels
43
Post synaptic protein that directly control gene expression
CREB
44
Enzyme that carries out phosphorylation
Kinase
45
Protein attached to the axon terminal that controls docking & exocytosis of synaptic vesicle
SNARE
46
Protein that degrades neurotransmitter within synaptic space
Hydrolytic enzyme
47
Synaptic vesicle protein that docks vesicle to axon terminal
synaptobrevin
48
Most neurotransmitters are derived from this type of molecule
Amino acid