Migraine Medications

Question 1

What are the Triptan migraine drugs?

Answer 1

Sumatriptan, Almotriptan, Naratriptan, Zolmitriptan, Rizatriptan, Eletriptan, Frovatriptan

Question 2

What is the name of the Ergot Alkaloid drug?

Answer 2

Dihydroergotamine

Question 3

Which Triptans have the best delivery?

Answer 3

Sumatriptan, Zolmitriptan

Question 4

Which Triptans have the most immediate relief?

Answer 4

Sumatriptan, Zolmitriptan

Question 5

Which Triptan has the longest relief?

Answer 5

Frovatriptan

Question 6

Which receptors do Triptans bind to?

Answer 6

5HT-1B (blood vessels), 5HT-1D (nerves/dura)

Question 7

Which Triptans are contraindicated if the pt. is on an MAO inhibitor?

Answer 7

Sumatriptan, Zolmitriptan, Rizatriptan

Question 8

Which Triptans are contraindicated if the pt. has a history of coronary artery disease or uncontrolled HoTN?

Answer 8

ALL Triptans

Question 9

What are the major side effects of Ergot Alkaloids?

Answer 9

Emesis, extreme vasoconstriction (gangrene)

Question 10

Which has a quicker relief, Triptans or Ergot Alkaloids?

Answer 10

Triptans

Question 11

Which has a longer relief, Triptans or Ergot Alkaloids?

Answer 11

Ergot Alkaloids

Question 12

What are the ß blockers that can be used to prevent migraines?

Answer 12

Propranolol, Timolol

Question 13

What are the tricyclic antidepressants that can be used to prevent migraines?

Answer 13

Amitriptylene, Imipramine

Question 14

Which drug is the first choice for migraine prevention and what is its MOA?

Answer 14

Verapamil –> Ca channel blocker

Question 15

Which type of pt. is a ß blocker contraindicated for?

Answer 15

Asthma pt.

Question 16

How does Botox prevent migraines?

Answer 16

Cleaves SNAP-25 inhibiting vessel fusion and NT release