Minimal Change Disease Flashcards
1
Q
What causes minimal change disease?
A
Unknown
seen 2-4 day after throat infection
2
Q
Age range?
A
Most common glomerulonephritis in kids
3
Q
Symptoms?
A
Nephrotic syndrome
4
Q
What is nephrotic syndrome?
A
> 3.5g/day proteinuria
Hypoalbuminaemia - oedema
Hyperlipidaemia - lipiduria
5
Q
What is different about the proteinuria in minimal change
A
Selectively only albumin
6
Q
What tests?
A
Minimal change disease
- No difference on any renal biopsy levels
Just monitor and treat
7
Q
What is the treatment?
A
Prednisolone
Other immunosuppression
- Cyclophosphamide
- Cyclosporin
- Tacrolimus
- Rituximab
8
Q
What percentage progress to ESRF?
A
1%
