Misc Flashcards

1
Q

Aortic stenosis in pregnancy

A

Maintain AFTERLOAD! avoid hypotension, avoid tachycardia!

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2
Q

Mitral stenosis in pregnancy

A

AVOID AFIB! DIURESIS TO AVOID PULM EDEMA. treat with beta blockade

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3
Q

teratogenicity of mycophenolate associated with”

A

microtia, cleft lip and palate, cardiac defect

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4
Q

informed consent, ethical principle of?

A

autonomy

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5
Q

After prolonged pushing, pt. suffers foot drop, which nerve is affected

A

peroneal nerve

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6
Q

what cytokines are most likely involved in septic shock?

A

TNF alpha, IL-1

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7
Q

most commonly acquired congenital viral infection

A

CMV

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8
Q

what infectious agent which caused IUFD associated with placental abscesses

A

listeria

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9
Q

what type of twins with cleavage at day 5?

A

MCDA

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10
Q

how to diagnose ARDS?

A

new or worsening respiratory symptoms with bilat opacities not fully explained in vented patient with PEE> 5 … PaO2/FIo2 < 300!

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11
Q

highest yield in determining cause of stillbirth

A

placental pathology

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12
Q

how to get karyotype after IUFD for most likelihood of results

A

amniocentesis

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13
Q

precursor of placental estrogen?

A

DHEAS

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14
Q

precursor of placental progesterone

A

cholesterol

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15
Q

what enzyme does fetus have that placental does NOT for steroid synthessis?

A

17 alpha hydroxylase (biosynthesis of cortisol and androgens)

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16
Q

most common fetal effect in untreated PKU?

A

intellectual disability

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17
Q

PRECONCEPTION W/ TRANSPLANT- tell patients… most likely good outcome

A

creatinine level < 1.5

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18
Q

most prevalent aneuploidy with CDH?

A

Trisomy 18

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19
Q

Hardy weinberg dizease frequency of mutation

A

q2

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20
Q

carrier frequency?

A

2PQ

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21
Q

why dont we use nitroprusside?

A

reflex tachycardia, cyanide toxicity

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22
Q

CCB adverse drug effect

A

Headache, hypotension, peripheral edema, flushing

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23
Q

causes of low estriol?

A

placental steroid sulfatase deficiency, smith lemli opitz, CAH, anencephaly

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24
Q

how to monitor improvement in DKA

A

anion gap

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25
surfactant has highest concentration of what phospholipid
PHOSPHOTIDYLCHOLINE (aka lecithin)
26
dermatosis with worst pregnancy outcome?
impetigo herpetiformis
27
what is the most common sex chromosome aneuploidy?
Klinefelter XXY
28
NT alone has sensitivity of what for dx of T21?
70%
29
what anatomic finding most associated with T21?
absent nasal bone/hypoplastic nasal bone
30
myelomeningocele MOMS in utero repair most benefit
decrease need for shunt placement
31
ADE of CCB?
peripheral edema, headache, hypotension
32
most confirmatory of primary CMV infection?
increasing IgG titer, 2-4 fold
33
amnio acid transport across the placenta by?
active transport
34
Medications most likely to be passed through breast milk?
lipid soluble
35
what cytokines are antiinflammatory
IL 10, IL 4
36
What cytokines are PRO inflammatory
IL 6, IL 8, TNF alpha, Interferon
37
what does an ROC curve represent?
diagnostic ability of binary classifier, True positive rate (SENSITIVITY) against false pOS rate (1-SPEC)
38
HYPERemesis with tingling/numbness/confusion... what do you need?
Thiamine! B1! wernickes enceph
39
what is the most likely complication from first trimester varicella infection
NOTHING! risk is very low@
40
in the intervillous space, maternal blood in contact with?
syncitiotrophoblasts
41
US feature with fetal alcohol syndrome?
microcephaly
42
mitral stenosis most likely to decompensate postpartum due to?
increased preload
43
which crosses thyroid molecule placenta most rapidly
TRH
44
PaO2 in the umbilical artery is approximately?
20
45
which vessel has the most oxygenated blood?
umbilical vein --> ductus venosus
46
best treatment for pheochromocytoma in pregnancy?
alpha blocker (phenoxybenzamine)
47
what infection is most likely associated with PVL?
chorioamnionitis
48
wedge pressure is indicative of?
LV preload
49
mechanism of action for beta agonist?
activation of adenyl cyclase, which then increases cAMP, activate PKP, reduce Ca+2, prevent smooth muscle contraction
50
for whcih infection does prenatal treatment prevent transmission to fetus?
hepatitis B
51
which prostaglandin relaxes the uterus
prostacyclin
52
renal dosing for dopamine
4 *(less than 5!)
53
what type of connections are most protective in TTTS?
AA
54
how do you compare multiple MEANS
anova
55
How do you treat listeria? what about if PCN allergic?
Amoxicillin/Bactrim
56
what steroid most associated with sodium resorption?
fudrocortisone
57
what antibiotic potentiates the neuromuscular blockade effect of magnesium?
gentamycin
58
what is the most common complication of malaria in pregnancy? plasmodium falciparum
maternal anemia
59
ductus arteriosus receives blood from?
pulmonary artery
60
when to intubate pregnant patient?
PaCO2 > 40
61
PFT: what increases in pregnancy?
TV, IC, pO2, alveloral vent
62
PFTs: what decreases in pregnancy?
TLC, ERV, FRC, RV, pCO2
63
what is the most common complication of prematurity
respiratory distress syndrome