Misc

Question 1

1. Causes of erythema mutliforme

Answer 1

lamotrigine

Question 2

. Obese, NIDDM ♀ with abnormal LFT’s →

Answer 2

NASH (non-alcoholic steatotic hepatitis)

Question 3

Fluctuating level of conciousness in elderly plus/minus deterioration →

Answer 3

chronic
subdural. Can last even longer than 6 months

Question 4

. Sensitivity →

Answer 4

TP/(TP plus FN)

Question 5

9. Ipsilateral ataxia, Horners, contralateral loss pain/temp →

Answer 5

PICA stroke (lateral medulary
syndrome of Wallenburg)

Question 6

yperprolactinemia (gallactorrohea, amenorrohea, low FSH/LH) → causes are:

Answer 6

causes are:
(metoclopramide, chlorpromazine, cimetidine NOT TCA’s), pregnancy, PCOS, pit
tumor/microadenoma, stress.

Question 7

. Episodic headache with tachycardia →

Answer 7

Pheochromocytoma

Question 8

Diagnosis of CLL →

Answer 8

immunophenotyping NOT cytogenetics, NOT bone marrow

Question 9

Pancytopenia with raised MCV →

Answer 9

check B12/folate first (other causes possble, but do
this FIRST). Often associayed with phenytoin use → ↓ folate

Question 10

.Prognostic factors for AML →

Answer 10

bm karyotype (good/poor/standard) → WCC at
diagnosis.

Question 11

.Pancytopenia with raised MCV →

Answer 11

check B12/folate first (other causes possble, but do
this FIRST). Often associayed with phenytoin use → ↓ folate

Question 12

Anosmia, delayed puberty →

Answer 12

Kallmans syndrome (hypogonadotrophic hypogonadism)

Question 13

. Commonest finding in G6PD hamolysis →

Answer 13

haumoglobinuria

Question 14

Flank pain, urinalysis:blood, protein →

Answer 14

renal vein thrombosis. Causes: nephrotic
syndrome, RCC, amyloid, acute pyelonephritis, SLE (atiphospholipid syndrome which is recurrent thrombosis, fetal loss, dec plt. Usual cause of cns manifestations assoc with LUPUS ancoagulant, anticardiolipin ab)

Question 15

Hypothermia, acute renal failure →

Answer 15

rhabdomyolysis (collapse assumed)

Question 16

Burning, Pain, numbness anteriolateral thigh →

Answer 16

meralgia paraesthesia (lat cutaneous
nerve compression usally by by ing ligament)

Question 17

Diagnosis of hemochromatosis:

Answer 17

screen with Ferritin, confirm by tranferrin saturation,
genotyping. If nondiagnostic do liver biopsy 0.3% mortality

Question 18

.40 mg hidrocortisone divided doses (bd) →

Answer 18

10 mg prednisolone (ie. Prednislone is x4
stronger)

Question 19

Diptheria →

Answer 19

exudative pharyngitis, lymphadenopathy, cardio and neuro toxicity.

Question 20

Indurated plaques on cheeks, scarring alopecia, hyperkeratosis over hair follicles
→

Answer 20

Discoid LUPUS

Question 21

Wt loss, malabsoption, inc ALP →

Answer 21

pancreatic cancer

Question 22

Fever, lymphadenopathy, lymphocytosis, pharygitis →

Answer 22

EBV → heterophile antibodies

Question 23

GI bleed after endovascular AAA Surgery →

Answer 23

aortoenteric fistula

Question 24

Functional hypogonadotrophic hypogonadism →

Answer 24

amennorhea. LH and FSH both low. All other hormones are usually normal. Ferritin low.

Question 25

Reiters Syndrome –

Answer 25

arthritis, uveitis, urethritis – Chlymidia, campylobacter, Yersinia, SALMONELLA , Shigella. Balanisits.

Question 26

PKD –

Answer 26

aut dom Chr 16/4 assoc berry aneurysm, mitral/aortic regurg

Question 27

Diag of PKD →

Answer 27

renal US even if think anorexia nervosa

Question 28

Porphyria –

Answer 28

photosensitivity, blisters, scars with millia, hypertrichosis

Question 29

Vitiligo –

Answer 29

commonest assoctions pernicious anemia → type 1 DM , autoimmune addisons, autoimmune thyoid dx

Question 30

Peripheral neuropathy –

Answer 30

a) B12 – rapid, dorsal columns (joint pos, vibration), sensory ataxia, pseudoathetosis of upperlimbs b) diabetic – slow, spinothalamic (pain, temp?) c)alcohol – slow progressive, spinothalamic d) Pb – motor upper limbs

Question 31

CNS abnormalities in HIV:

Answer 31

: toxoplaasmosis (ring enhancing), lymphoma (solitary lesion). HIV encephalopathy, progressive multifocal leucoencephalopathy (PML – demylination in advanced HIV, low attenuation lesions)

Question 32

Travellers diarrohea:

Answer 32

chronic (>2 WEEKS) giardia (incidious onset rx. Metronidazole), SALMONELLA (serious systemic illness), E.coli (rx. Ciprofloxacin) , Shigella

Question 33

Renal syndrome –

Answer 33

minimal change disease, membanous, IgA nephropathy, post- streptococcal.

Question 34

Thyroid Malignancy –

Answer 34

tend to be non-functional, anaplastic has worse prognosis, local infiltration → dysphagia, vocal cord paralysis

Question 35

. Silvery white scale →

Answer 35

PSORIASIS

Question 36

Hypopigmented →

Answer 36

vitiligo/pityriasis versicolor

Question 37

Pretibial myxedema →

Answer 37

Graves (NOT lid lag, NOT exopthalmus)

Question 38

R. Arthritis with nephritic syndrome →

Answer 38

looks for amyloidosis, even by rectal biopsy.

Question 39

Cushing investigation

Answer 39

Overnight Dexamethasone Test

Question 40

Cushing- vs. Pseudo-cushing

Answer 40

insulin Stress Tes

Question 41

Acromegaly

Answer 41

Oral Glucose Tolerance Test