Flashcards in Misc Bacteria Deck (13):
Obligate intracellular bacteria (cannot make ATP), has 2 forms, cell wall lacks muramic acid, cultured in tissue cultures, causes 3 distinct diseases, infects nonciliated columnar or cuboidal epithelial cells of mucosal surfaces that causes a granulomatous response and damage
Most common bacterial STD in US, causes urethritis, cervicitis, PID, can causes inclusion conjunctivitis or pneumonia in neonates (pneumonia characterized by staccato cough)
Chlamydia trachomatis, serotypes D-K
Infectious form of chlamydia? Replicating form?
Infectious = elementary body
Replicating = reticulate body
STD causing swollen lymph nodes that may lead to elephantiasis, ulcers, or fistula formation
Lymphogranuloma venereum caused by Chlamydia trachomatis, serotypes L1, 2, 3
Leading cause of preventable infectious blindness, causes follicular conjunctivitis that leads to inturned eyelashes and corneal scarring
Trachoma, causesd by Chlamydia trachomatis serotypes A-C
Cause of atypical pneumonia associated with atherosclerosis, diagnose with serology
Cause of atypical pneumonia associated with hepatitis, no glycogen seen in inclusion bodies, associated with exposure to parrots or turkeys, diagnose with serology
Aerobic bacilli, technically G- but too small to stain, obligate intracellular, transmitted by Dermacentor tick, invades endothelial cells to cause vasculitis, highest incidence in North Carolina
Symptoms of Rocky Mountain Spotted Fever?
headache, fever, myalgias, vomiting, confusion, maculopapular -> petechial rash that starts on ankles and progresses to trunk and face, ankle and wrist swelling
G- obligate intracellular bacilli, found in same geographic area and transmitted by same tick as Borrelia, presents similarly to Rocky Mountain Spotted Fever but without the rash, causes a morulae (mulberry like structure inside infected cell)
Smallest extracellular bacteria, no cell wall, requires cholesterol for culture, grows mulberry colonies on Eaton's media, positive cold agglutinins, causes an atypical pneumonia
Virulence factors of M. pneumoniae?
P1 protein - attachment
Inhibition of ciliary action
Produces H2O2, superoxide radicals, and cytolytic enzymes that damage the respiratory epithelium
Superantigen elicits IL1, IL6, TNF-a