(-) RNA Viruses Flashcards Preview

Microbiology Rapid Review > (-) RNA Viruses > Flashcards

Flashcards in (-) RNA Viruses Deck (17):
1

Enveloped paramyxoviridae, helical, H glycoprotein and fusion protein, causes cell to cell fusion and a syncytium of giant cells, live vaccine

Measles

2

Cough, coryza, conjunctivitis with photophobia, red grains on sand on buccal mucosa, maculopapular rash

Measles virus

with Koplik spots, can progress to pneumonia with Warthin-Finkeldey cells

3

Rare late complication of measles virus involving CNS

Subacute sclerosing panencephalitis

4

Helical enveloped paramyxoviridae, HN glycoprotein and F protein, causes lytic infection of epithelial cells of URT and parotid glands that may eventually spread throughout the body, live vaccine

Mumps virus

5

Name the "-itis's" present in mumps

bilateral parotitis (painful), pancreatitis, orchitis (leading to sterility), meningoencephalitis

6

Helical enveloped paramyxoviridae, causes barking cough in infants

Parainfluenza virus (croup)

7

Helical enveloped paramyxoviridae, causes bronchiolitis and atypical pneumonia in preemies, treat with ribavirin

Respiratory Syncytial Virus

8

Helical enveloped paramyxoviridae, causes 15% of common cold in kids

Human metapneumonia virus

9

Helical enveloped rhabdovirus, binds to peripheral nerves by binding nicotinic ACh receptors or indirectly binds to muscle, causes CNS infection that is rapidly fatal, immunoglobulin and killed vaccine available for post exposure prophylaxis

Rabies

10

Non-specific flu like illness followed by hydrophobia, seizures, disorientation, hallucinatinon, coma, death

Rabies

11

Intracytoplasmic inclusion bodies seen in brain with Rabies infection

Negri bodies

12

Enveloped, helical, filamentous filoviridae, direct contact transmission, causes fatal hemorrhagic fever, calls for Level 4 isolation

Ebola and Marburg viruses

13

Enveloped helical segmented orthomyxoviridae, two envelope glycoproteins H (binds sialic acid and allows entry) and N (binds mucous to allow virus to travel), pathogenesis involving antigenic drift (causing epidemics) and shift (causing pandemic)

Influenza virus

A - humans and animals
B - humans only

14

What type of vaccine is available for Influenza?

Killed - incorporated strain, most used in U.S.

Live - intranasal administration

15

Enveloped bunyavirus, associated with the rainy season and exposure to rodent excrement, causes a pulmonary syndrome with cough, dyspnea, tachycardia, pulmonary effusion, leg aches, and cramps

Hantavirus

16

Pleomorphic enveloped arenaviridae with sandy appearance due to ribosomes in virion

Lymphocytic choriomeningitis virus - mice/hamster, influenza like with meningitis

Lassa fever - eating rats in Africa, hemorrhagic fever

17

dsRNA, fecal oral transmission, naked icosahedral, reovirus, causes gastroenteritis in infants with no pus or blood in stool

Rotavirus