Misc Kidney Physiology Flashcards Preview

Organ Systems- Renal > Misc Kidney Physiology > Flashcards

Flashcards in Misc Kidney Physiology Deck (23):
1

What are the 4 functions that can give an indication of Kidney Function ?

1. GFR
2. Plasma Clearance of Solutes
3. Renal Blood Flow

2

Why is Inulin useful in ascessing kidney function ?

It is not produced by the body, metabolized by the body. It is excreted by the kidney. It is not reabsorbed or secreted.

3

How do you calculate GFR ?

UF x Uin / Pin
-UF is urine flow
-Uin is urine inulin
-Pin is plasma inulin

4

What is clearance ?

The volume of plasma cleared of a substance per unit time

5

If clearance of a substance is less than GFR what does that mean ?

The substance is reabsorbed

6

If clearance is greater than GFR what does that mean ?

The substance is secreted.

7

What is the extraction ratio ?

The fraction of substance removed from the plasma.

8

Plasma Inulin =

Rate of Infusion / Rate of Output

9

Filtration Rate =

GFR x Px

10

Excretion Rate =

UF x Ux

11

What are the 4 routes substances move in the kidney ?

Vein, Artery, Ureter, Lymph

12

Is NaCl produced in the body ?

Is Urea Ingested ?

No- you only have to worry about ingestion and excretion

No you only have to worry about production and excretion.

13

What is mass flow ?

It expresses solute movements as a function of time.

14

What is the extraction ratio of X ?

Ax - Vx [renal venous] / Ax

15

What will reabsorption do to the extraction ratio ?

It will lower it

16

What will secretion do to the extraction ratio ?

It will raise it .

17

What do you use to measure renal plasma flow ?

Para amino hippuric acid

18

What is the clearance rate of Creatine ?

140 ml per min

19

How much creatine does the body make a day ?

2 g

20

How do you calculate the renal plasma flow ?

C (pah) / Extraction Ratio

21

How do you get renal blood flow from renal plasma flow ?

You get renal blood flow by dividing the plasma flow by ( 1 - hemacrit )

22

What is the plasma flow of PAH ?

0.9 - 0.95

23

What is C pah ?

It is a measure of effective renal plasma flow.

Cpah = (UF c Upah) / Ppah