Misc: Medical Marijuana

Question 1

The endocannabinoid system (ECS) affects what 5 things?

Answer 1

• sleep
• mood
• appetite
• memory
• bone growth

Question 2

What are the 2 major cannabinoid receptors?

Where are they located in our nervous system?

Answer 2

• CB1: CNS

- CB2: PNS, immune cells

Question 3

What is the main psychoactive compound in cannabis?

Answer 3

THC: delta-9-tetrahydrocannabinol

Question 4

THC has primary activity on what receptor?

Answer 4

CB1

Question 5

THC is metabolized by what cytochrome?

Answer 5

cytochrome P450

Question 6

What is marinol (dronabinol) and casamet (nabilone) used for?

Answer 6

nausea/vomiting from chemotherapy and appetite stimulant for AIDS related wasting syndrome

Question 7

What is savitex (nabiximols) used for?

Answer 7

symptomatic relief from MS and analgesia for cancer

Question 8

What is CBD approved for?

Answer 8

epilepsy

Question 9

What are the side effects of CBD?

Answer 9

• nausea, dry mouth, fatigue

Question 10

What is the most important thing about edibles?

Answer 10

variable onset times

“suggest start low, go slow”

Question 11

You should wait at least ____ hours before driving or operating heavy machinery.

Answer 11

4 hours

Question 12

If using edibles, start with a small dose of _____ mg THC and wait an hour before consuming more.

Answer 12

10-25 mg

Question 13

The highest % of use disorder in the past year was in what age group?

Answer 13

18-25 yo

Question 14

T/F: Marijuana addiction is possible, though not as common as other legalized substances, and riskier the younger someone is when they start

Answer 14

True

Question 15

Genetic disposition to ___________ is associated with an increased risk of cannabis use.

Answer 15

schizophrenia

Question 16

What is the adverse effect of marijuana on patient’s with bipolar disorder?

Answer 16

may increase manic symptoms

some association between suicide attemp

Question 17

Holding long pulls of a joint or hit is associated with what respiratory problem?

Answer 17

pneumothorax

Question 18

What is the acute change in HR and BP with marijuana use?

Answer 18

increase HR and BP d/t sympathetic NS activation

Question 19

There is an increase in MI risk with marijuana use in what age group?

Answer 19

<50

Question 20

Cyclic vomiting and abdominal pain after marijuana use is consistent with what diagnosis?

Answer 20

marijuana hyperemesis syndrome

Question 21

What patient qualifies for medical cannabis in MA?

Answer 21

A MA resident 18 years of age or older who has been diagnosed by a Certifying Healthcare Provider as having a debilitating medical condition

Question 22

What is the medical cannabis limit in MA?

Answer 22

10 oz of cannabis / 60 days

Question 23

What is the risk of driving with marijuana use?

Answer 23

2-3x increased risk of car crash

Question 24

Roadside tests for marijuana cannot shown _____ someone used.

Answer 24

when