MIT7.00x Flashcards

(23 cards)

1
Q

What are the four classes of macromolecules that comprise a cell?

A

lipids, proteins, nucleics, and carbohydrates

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2
Q

What are the layers of biology?

A
Biospheres ie. earth
Ecosystems ie. the galapogos
Organism ie. a chimp
Organ ie. the intestine
Tissues
Cells
Organelles
Molecules
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3
Q

How many years ago did the earth form?

A

4.5 billion years

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4
Q

How many years ago did it take for earth to cool enough for life to survive?

A

4 billion years

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5
Q

When did life first show up?

A

3.7 billion years ago prokaryotic cells first show up (only took 300 million years)

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6
Q

How long did it take for life to evolve from prokaryotic to eukaryotic?

A

2 billion years! Nucleated cells showed up 1.5 billion years ago

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7
Q

When did multicellular life show up?

A

0.5 billion years ago

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8
Q

When did human like creatures show up?

A

0.005 billion years ago

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9
Q

When did humans show up?

A

0.0001 billion years ago

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10
Q

When did humans show up?

A

0.0001 billion years ago

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11
Q

What is the approximate size of an animal/plant cell?

A

10-40 microns

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12
Q

What is the approximate size of an animal/plant cell?

A

10-40 microns

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13
Q

What were the two primary ways of studying life in the 21st century?

A
  1. biochemistry (understand life by studying one component in isolation by purifying one element away from the others). Primarily studying proteins.
  2. genetics, geneticists study the whole organism but take away one component (change one gene)
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14
Q

What brought biochemistry and genetics together?

A

molecular biology because it allowed us to connect DNA to biochemistry so now we could connect genetics to biochemistry

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15
Q

What was the impact of recombinant DNA?

A

It allowed you to take a single gene and manipulate it. This took us into the 1980’s

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16
Q

In the first decade of the 21st century how much did the cost of sequencing fall?

A

A million fold. A million fold delta in 10 years!

17
Q

When did vitalism die?

A

It died towards the late 1890’s Buchner proved that ‘yeast juice’ can perform fermentation. This is where the name for enzymes came from. Vitalism came about because it was thought only living things could do fermentation

18
Q

When did vitalism die?

A

It died towards the late 1890’s Buchner proved that ‘yeast juice’ can perform fermentation. This is where the name for enzymes came from. Vitalism came about because it was thought only living things could do fermentation

19
Q

What is the approach biochemists take?

A

Grind life up into molecules

20
Q

What is lifes approximate elemental fractions?

A
Hydrogen 2/3
Oxygen 1/4
Carbon 1/10
Nitrogen 1/100
Phosphorous 1/1000
Sulfur < 0.1%
21
Q

What is lifes approximate elemental fractions? What are the elements of life?

A
Hydrogen 2/3
Oxygen 1/4
Carbon 1/10
Nitrogen 1/100
Phosphorous 1/1000
Sulfur < 0.1%
22
Q

What is lifes approximate atomic fractions? What are the elements of life?

A
Hydrogen 2/3
Oxygen 1/4
Carbon 1/10
Nitrogen 1/100
Phosphorous 1/1000
Sulfur < 0.1%
23
Q

What is the molecular composition of life?

A

Water 80%

Dry weight...
50% protein
15% carbs
10% lipids and fats
15% nucleic acids