mitosis Flashcards

1
Q

mitosis happens

A

after fertilization
during growth and developments
to replace dead or damaged cells

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2
Q

meiosis happens

A

only in gonads in animals and in structured cells in plants

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3
Q

mitosis vs meiosis

A

mitosis: 2 dauther cells, same number pf chromosomes as parent cell
meiosis: 4 daughter cells, half number of chormosomes as parent cell

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4
Q

autosomes/sex chromosomes

A

autosomes are 22, body chromosomes,
sex chromosome: 23rd, X or Y

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5
Q

karyotype

A

profile of a persons chromosomes

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6
Q

gamets number of sets of chromosomes

A

1 set (haploid)

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7
Q

diploid

A

2 sets, autosomes in humains are diploid

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8
Q

homologous pairs

A

chromosomes come in homologous pairs (one from each parent, same lenght, shape and genetic information, talk about same things)

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9
Q

alleles

A

alternate versuons of same genes on chromosoe, genes at same locus. can code for same or different thing

2 alleles: blood A type and Blood B type ex

for women, sex chromosomes (XX) contain 2 copy of genetic material, if one is mutated the second one can come to rescue. For men (XY) only one copy of what is on the X specific region, and 1 copy of whats on the y specific region

homologous reagion for both (tiny bottom, copies on XY too)

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10
Q

stem cells

A

in gonads: stem cels maintain the stem cell population by mitosis
in response to hormones, stem cells will go through meiosos and become gametes (haploid). they have left the cell cycle

in rest of body: stem cels maintain the stem cell population by mitosis
in response to chemical signal, stem cells will get differentiated to replace other cells for ex they have left the cell cycle

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11
Q

cells in cell cycle

A

interphase : G1, S, G2
cell division (mitosis)
cytokinesis (division of cytoplasm)
back to interphase

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12
Q

cells outside of cell cycle

A

Cells are in G0
performing their job as a neuron for example
making new organelle as needed

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13
Q

mitosis phase

A

(nuclear replication)

prophase: chromosomes condense to facilitate movement and keep safe. Mitotic spindle/ spindle fibers are just being assembled, nuclear envelop still intact.
Prometaphase: nuclear envelope breaks down, mitotic spindle complete and attaching to all condensed replicated chromosomes
metaphase: chromosomes area aligned at the metaphase plate by the spindle fibers.
anaphase: early: sister chromatids seperated by mitotic spindle fibers and are now called unreplicated chromosomes. Later: chromosomes being moved towards centrioles (at pole) by spindle fibers
telophase: chromosomes at pole, cleavage furrow present

Once nuclear enevlope reforms, chromosomes decondense mitosis is complete !! cell is in late cytokinesis

meiosis same only with meiosis 1 (1 all phases), cytokinesis, meiosis 2 (2 all phases), cytokinesis

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14
Q

interphase

A

takes the longuest

G1 (gap 1): most organelles are replicated
S phase: copy all the chromosomes, sythesize DNA and associated proteins. now 2 identical sister chromatids, connected at their centromeres
G2: centrioles druplicated and make other proteins that will be needed

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15
Q

cytokinesis

A

division of cytoplasm, begins in telophase but not part of mitosis

ring of protein filaments encircles the cell (cleavage furrow) and contracts to split into 2 daughter cells

cytokinesis is complete when 2 daughter cells are formed, mitosis is complete when nuclear enveloppe formes (can be 1 parent cell with 2 nuclei)

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16
Q

mitosis in plants

A

same but no centrioles
cytokinesis is different: golgi formes a line of vesicles that fuses to become plasma membrame and cell plate

17
Q

mitosis in haploid cells

A

same but no homologous chromosomes

18
Q

cell cylce in bacteria

A

reproduce by binary fission, not mitosis, prokaryotes never do mitosis,
cytokinesis : cleavage furrow and spetum (new dividing wall) forms in the middle of the cell, 2 cells released and continue their lives as 2 bacteria

19
Q

checkpoint

A

critical control point to regulate cycle, stop or go ahead

G1 checkpoint: cell size
nutrients
growth factors
DNA damage

G2 checkpoint: cell size
DNA replication

Spindle assembly checkpoint: chromosomes attachment to spindle

if not the resting state G0

Gene mutation can lead to loss of cell cycle regulation, can lead to tumor