Mitosis: Division Is Also Multiplication Flashcards

(44 cards)

1
Q

Cell division starts with ______ which has 3 subphases

A

Interphase

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2
Q

3 subphases of interphase

A

G1
S
G2

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3
Q

Next 4 phases of cell division

A

Prophase
Metaphase
Anaphase
Telophase

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4
Q

______ are found in the different stages of cell division that monitor cell division, ensuring its smooth process

A

Checkpoints

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5
Q

G stands for

A

Gap

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6
Q

In ____, the cell synthesizes MRNA and proteins, which are needed for chromosome replication

A

G1

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7
Q

2 checkpoints in G1

A
G1 DNA damage checkpoint
p53 proteins (TP53)
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8
Q

It evaluates the dna’s integrity

A

G1 DNA damage checkpoint

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9
Q

Damaged DNA results in the accumulation of p53 proteins that can trigger either _______ or _______

A

Cell cycle arrest or apoptosis

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10
Q

Are tumor-suppressing proteins that help in regulating the cell cycle

A

p53 proteins (TP53)

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11
Q

Refers to a process of programmed cell death

A

Apoptosis

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12
Q

It evaluates the cell’s capability to undergo cell division

A

Restriction checkpoint

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13
Q

If the cell is ready, it will proceed to S phase, if not, the cell goes to

A

G0

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14
Q

2 cells in G0

A

Quiescent (dormant)

Senescent (aging or deteriorating)

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15
Q

It may go back to cell division with proper stimulus

A

Quiescent cells

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16
Q

One reason cells become senescent is due to

A

damaged DNA

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17
Q

In this phase, chromosomes are replicated which means that there are twice the actual DNA now present in the cell

A

S (synthesis) phase

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18
Q

Each chromosome consists of two _____, which is one copy of a newly copied chromosome

19
Q

It monitors the replication process during the S phase

A

S DNA damage checkpoint

20
Q

At this point, the cell rapidly grows and protein synthesis continues

21
Q

It checks activities in G2 to ensure its proper flow

A

G2 DNA damage checkpoint

22
Q

It ensures that DNA synthesis is complete before proceeding to mitosis

A

Unreplicated DNA checkpoint

23
Q

The chromosomes condense and are now visible even with just using the ordinary light microscope

24
Q

A chromosome consists of two sister chromatids attached to the

A

Single centromere

25
In the late part of prophase, the ______ and the _______ disappear
Nuclear envelope and nucleolus
26
A special protein complex appears at the centromere at prophase. Its function is to link the spindle fibers to the centromere
Kinetochore
27
3 kinds of microtubles in the spindle fibers
Astral microtubules Polar microtubules Kinetochore microtubules
28
A kind of microtubules that grow only near the centrosome (the structure with the centrioles)
Astral microtubules
29
A kind of microtubules that grow away from the centrosome. These overlap ay the middle where the chromosomes are located, but they are still attached to the kinetochore
Polar microtubules
30
A kind of microtubules that are onlu ones attached to the kinetochore
Kinetochore microtubules
31
In metaphase, the kinetochore microtubule directs the chromosomes toward the center that is called
Metaphase plate or equatorial plate
32
It guarantees the proper alignment of the chromosomes at the metaphase plate and prevents untimely onset of the anaphase
Spindle assembly checkpoint
33
Twi substages in anaphase
Anaphase A | Anaphase B
34
In anaphase _, the kinetochore microtubules of the spindle fibers separate and move the sister chromatids toward opposite poles
A
35
In anaphase _, the polar microtubules begin to elongate, while astral microtubulea pull them on the other side.
B
36
Is the process of dividing the cytoplasm into half. It starts at anaphase and continues to the next phase
Cytokinesis
37
In _____, the chromosomes uncoil, and both the nucleolus and the nuclear envelope reappear
Telophase
38
Cytokinesis, in telophase, continues with the visible appearance of the _____, a groove on the cell membrane between the poles usually observed in animal cells
Cleavage furrow
39
In animal cells, the cleavage furrow is produced when the _______, which is made up of proteins, constricts the middle of the cell. This continues until the opposite surfaces of cell membrane are in contact and produces 2 daughter cells
Contractile ring
40
It prevents cytokinesis to start until all chromosomes are correctly separated.
Chromosome segregation checkpoint
41
The cell wall of plants is a strong substance thus a _________ forms which is involved in forming the cell wall of each daughter cell in plants
Cell plate
42
Mitosis ensures that the number of chromosomes of the parent cell is identical to
Its 2 daughter cells 46 chromosomes from parent cell Two 46 chromosomes daughter cells
43
Purposes of mitosis
* ensures that the number of chromosomes of the parent cell is identical to its two daughter cells * ensures the growth of the offspring * replaces the damaged cells in the wounds
44
Is simply defined as cells that undergo continuous division without stopping
Cancer