MIX 8 QBANK Flashcards

(246 cards)

1
Q

GB adverse effect of ceftriaxone

A

can cause GB SLUDGE

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2
Q

course of cystic artery compared to common hepatic duct

A

POSTERIOR

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3
Q

cystic artery variations

A

GDA
SMA
COMMON hepatic artery

Usually comes off RIGHT hepatic

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4
Q

primary source of bilirubin in the body

A

Senescent red blood cells

Whether due to aged cells or active hemolysis, hemoglobin is broken down into bilirubin and ultimately secreted into bile.

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5
Q

incidence of TIPS shunt stenosis

A

(up to 50%)

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6
Q

TIPS is what kind of shunt

A

side-to-side portosystemic shunt

nonselective shunt and completely diverts portal flow

TIPS is also effective in the treatment of medically intractable ascites

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7
Q

major cause of TIPS Shunt stenosis

A

neointimal hyperplasia

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8
Q

treatment of TIPS Shunt stenosis

A

often be resolved by balloon dilation

in some cases, by placement of a second shunt.

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9
Q

frequency of post-TIPS encephalopathy

A

(∼30%)

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10
Q

effectiveness of TIPS compared to endscopic tx of bleeding

A

TIPS more effective

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11
Q

effect of TIPS on pts requireing liver transplant

A

HELP temporize them!

does not mess with vasculature

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12
Q

risk factors associated with melanoma

A
UVA and UVB radiation
congenital nevi, 
dysplastic nevi, 
xeroderma pigmentosa,
family history

NOT actinic keratoses
(careful, actinic keratoses IS risk for squamous)

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13
Q

tx of Immediate sensory and motor deficits after creation of an arteriovenous fistula

A

requires immediate ligation

NOT DRIL

The DRIL (distal revascularization - interval ligation) procedure is used in patients that do not have dramatic symptoms in the immediate postoperative period

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14
Q

treatment of symptomatic Meckel’s diverticulum

A

Uncomplicated:
Diverticulectomy only

complicated:
Diverticulitis, GI bleeding, wide-based-
segmental resection

wait for obstructive symptoms to resolve?

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15
Q

Diagnosis of Zenker’s diverticulum

A

barium swallow

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16
Q

incision for opened Zenker’s diverticulum

A

left neck

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17
Q

when is a myotomy alone sufficient for Zenker’s

A

diverticulum less than 2 cm

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18
Q

when is diverticulo pexy performed for Zenker’s

A

elderly patients

LARGE diverticula to avoid complications of resection

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19
Q

prophylactic pre-incision antibiotics for colon surgery

A

second generation cephalosporin
cefoxitin
Cefotetan

or

Cefazolin and Flagyl

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20
Q

winded a therapeutic course of antibiotics recommended instead of just prophylactic pre-incision antibiotics for trauma

A

greater than 6 hours and time of injury

Signs of infection intraoperatively

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21
Q

symptoms of hypoglossal nerve injury

A

IPSILATERAL (towards the site of injury)

Tongue deviation

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22
Q

marginal mandibular nerve

A

branch of the facial nerve
“motor car”
Retraction and angle of mandible
Drooping of ipsilateral lip

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23
Q

site of injury from deceleration trauma of aorta

A

ligamentum arteriosum

just distal to subclavian

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24
Q

A 26-year-old female with a 3 cm heterogeneously enhancing hepatic lesion

A

adenoma

less than 4 cm and is asymptomatic, it does not need to be resected. If the patient is taking oral contraceptive pills (OCP), she should be advised to discontinue them.

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25
margin for hepatic colorectal cancer metastasis
1 cm Surgery give the best chance for cure
26
5 cm peripheral and centripetal enhancing hepatic lesion on CT
Cavernous hemangioma does not need resection unless symptomatic
27
A 36-year-old female with a left hepatic liver lesion that has a central stellate scar
focal nodular hyperplasia No malignant potential Does not need resection unless symptomatic or cannot be definitively differentiated from cancer
28
Treatment of hepatocellular carcinoma with involvement of the portal vein
no surgery
29
proper location to administer an ilioinguinal nerve block?
1 cm medial and 1 cm inferior to the anterior superior iliac spine
30
when does carcinoid syndrome develop
small bowel ( ileum) - large portion of the liver must be replaced with carcinoid tumor for symptoms careful, not with rectal
31
what our exceptions or carcinoid tumors develop more commonly with rare primary locations
organs the bypass hepatic circulation: Ovary Testes Lung these produce carcinoid syndrome without hepatic metastases
32
signs of air embolus
cardiovascular collapse, dysrrhythmias, characteristic “Mill wheel” murmur. pulmonary artery hypertension, elevated central venous pressure, jugular venous distension.
33
most common cause of dialysis unit is now having difficulty using the fistula long term
outflow stenosis - typically intimal hyperplasia occurs anywhere in the vein of an AV fistula or at the anastomosis of an AV graft
34
most common type of melanoma
superficial spreading initial growth a radial-been potential for vertical Careful, the prognosis is lentigo melanoma
35
most common melanoma an elderly
lentigo melanoma best prognosis
36
type of melanoma with worse overall prognosis
nodular–vertical growth phase
37
when do type II pneumothorax began to develop
24 weeks Careful, there is not adequate surfactant until 35 weeks Continue develop after birth
38
which is more common type I or type II pneumocytes sites
type II careful, lower surface area and a type II than type I however, type I cover 95% of alveolar surface
39
enzyme that activate trypsinogen and where it is found
enterococci Duodenum
40
enzymes that are secreted from the pancreas in active form
lipase Amylase ribonuclease
41
mechanism of trypsin and chemotrypsin
protein breakdown
42
extracolonic manifestations that will improve after colectomy for ulcerative colitis
erythema nodosum Arthritis Ankylosing spondylitis Pyoderma gangrenosum NOT PSC
43
treatment for primary sclerosing cholangitis
liver transplant
44
percentage of splenic artery aneurysms that present with year-old bleed; and percent mortality with rupture
20-30% present with abdominal pain and contained rupture and lesser sac - free rupture within 48 hours ( 20-50% rupture risk) 25% mortality with rupture 80-90% maternal and fetal mortality with rupture
45
treatment of splenic artery aneurysm
ligation or embolization of both the proximal and distal aspects of the aneurysm
46
most common side effects with pancuronium
tachycardia coronary artery disease relative contraindication
47
side effects of succinylcholine
``` hyperkalemia with: Spinal cord injury Burn Rhabdo - including prolonged immobilization renal disease Others: Malignant hyperthermia Rhabdomyolysis Ocular hypertension Muscle pain ``` used for rapid sequence intubation
48
clearance of vecuronium
BOTH liver and kidney
49
with organ dysfunction is Atracurium good for and what is a side effect
minimal cardiac fracture histamine release - vasodilated
50
pathophysiology of developing ascites from cirrhosis
fibrotic and parasites lead to portal hypertension Lymphatic bed of liver and splenic neck lymph nodes began to leak into the peritoneum This includes protein losses-hence the reason for albumin administration
51
mechanism of elimination of succinylcholine
pseudocholinesterase only depolarizing agent rapid onset and short half-life Patient's may be deficient in pseudocholinesterase - prolonged half-life
52
best prophylaxis for contrast-induced nephropathy
fluid hydration no significant benefits of: Mucomyst Bicarbonate Dopamine With hold: Loop diuretic ACE inhibitor Angiotensin II antagonists
53
Risk factors for contrast-induced nephropathy
``` multiple myeloma Proteinuria Diabetes mellitus Dehydration concomitant other nephrotoxic drugs Renal failure ```
54
what part of the kidney does contrast injure
renal tubule Transient regional ischemia
55
acute cholangitis bacteria
Escherichia coli Klebsiella Others: Bacteroides stridulous Streptococcus faecalis
56
the tissue named vessels branches of the external iliac artery
deep circumflex iliac: collateralizes with lateral femoral circumflex artery to the superior iliac spine also supplies collaterals to lower leg Inferior epigastric (careful, pelvis and abdomen origin) - this vessel anastomosis with superior epigastric artery which is a branch of the internal thoracic
57
management of splenic abscess
IV antibiotics splenectomy-particularly of multiloculated and complex possible IV antibiotics and CT-guided drainage-however, risky for bleeding only considered with unilocular simple abscess
58
time frame of intimal hyperplasia seen for graft stenosis
within 2 years of surgery
59
Cells involved with intimal hyperplasia
Spindle cells
60
Treatment of intimal hyperplasia and graft
Most effective after 6 months balloon angioplasty using cutting balloon early within 3 months: Patch angioplasty or vein graft
61
what timeframe does atherosclerosis of graft usually occur
after 2 years
62
most common location of indirect inguinal hernia sac compared to cord structures and cremasteric muscle
deep to cremaster Anterior and superior to spermatic cord - hernia sac is carefully Divided off of cord structures
63
when can sigmoid ischemia be watched after triple-A repair regarding endoscopic findings
ischemia limited to the mucosa Adequate perfusion Antibiotics and bowel rest
64
physical symptoms of myasthenia gravis
ptosis Diplopia Weakness with repetitive movements Fatigue
65
Percentage of myasthenia gravis patient who will have associated thymoma
only 10%! | thymectomy anyway
66
Percentage of patients with thymoma who will have myasthenia gravis
50%
67
percentage of improvement and myasthenia gravis after thymectomy
80%?
68
Pathway of conversion synthesis of catecholamine and adrenal medulla
``` Tyrosine - all starts with going in the ring L. dopamine - the dop Dopamine - gets dop Norepinephrine - starts getting adrenl Epinephrine - gets adren ```
69
only site of epinephrine production
adrenal medulla converting norepinephrine to epinephrine enzyme: PNMT - final step path
70
steps and reducing the phimosis and possible complication
dilated with surgical clamp Dorsal slit circumcision by urologist to temporize paraphimosis - prepuce is trapped behind the glans-this is a urologic emergency - arterial flow continues without any risk or lymphatic congestion
71
treatment of paraphimosis
neurologic emergency Emergent reduction required of pharphimosis in all circumstances
72
algorithm for hematochezia
NG lavage rule out upper GI NG lavage negative colon Bleeding intermittent and stable-colonoscopy Brisk bleeding: Colonoscopy not helpful can't see anything Localization study: Angiography-diagnostic and potentially therapeutic-requires bleeding rate of at least 0.5 mL per minute
73
Pathway of oxalate kidney stones and Crohn's
normally: Oxalate is bound into calcium oxalate and the bound form is excreted in the stool With Crohn's: steatorrhea and problems absorbing fat the fat competes to bind calcium (leaving the oxalate free) unbound oxalate reabsorbed by the colon and excreted by the kidney
74
treatment oxylate stone forming
calcium citrate exatra calcium precipitates dietary oxalate and citrate prevent stone formation and urine
75
syndrome of complete loss of adrenal function and potential cause
Waterhouse-Friderichsen syndrome is an adrenal gland hemorrhage that occurs after meningococcal sepsis infection also described with pregnancy
76
lab findings with adrenal insufficiency
hyponatremia - lost aldo HYPER kalemia - Hypotension fever sometimes hypoglycemia - cortisol def
77
Gram negative bacteria cause of sepsis
ENDOtoxin | ``` Lipid A within lipopolysaccharide component ```
78
hemangioma CT finding
Peripheral enhancement
79
treatment of hemangioma
increased size Symptoms Kasabach-Merritt syndrome.- Consumptive heart failure enucleation first choice May require segment segmentectomy NOT embolization
80
pressure the diagnosis portal hypertension
greater than 5 careful compared to IVC normal 0-5
81
portal pressure associated with esophageal variceal bleeding
–12
82
how is portal pressure calculated
difference between IVC and portal vein
83
best test to measure portal pressure and sinusoidal disease
e.g. cirrhotic | hepatic wedge
84
best test to measure portal pressure and pre-sinusoidal disease
EG schistosomiasis wedge is not good-falsely low measurement
85
exam finding that differentiated AV fistula from pseudoaneurysm
thrill in CHF fistula
86
findings with popliteal entrapment
palpable pulses Claudication with provocative activity We progressed the paresthesias
87
Anatomic etiology of popliteal entrapment
develops in utero! MEDIAL head of the gastroc Or developmental problem popliteal artery
88
40-year-old smoking female string of beads on CTA left internal carotid
fibromuscular dysplasia of the carotid artery
89
symptoms of fibromuscular dysplasia of the carotid artery
TIA Stroke Disability
90
diagnosis of fibromuscular dysplasia of the carotid artery
ultrasound and CTA possible angiogram string of beads
91
treatment of fibromuscular dysplasia of the carotid artery
asymptomatic : Antiplatelet therapy Symptomatic: Open - surgical dilation or angioplasty - gaining acceptance NOT stent-redundancy kink, coil not amenable to this
92
most important muscles involved an active expiration
``` rectus Internal oblique The external oblique Transversus abdominis Internal intercostal - pull the rib cage down external intercostal ```
93
femoral hernia tissue repair
McVay (Cooper's repair) approximate transversus abdominis aponeurosis to Cooper's ligament approach: Incision ABOVE inguinal ligament The external oblique aponeurosis split From external ring to internal ring-preserve ilioinguinal nerve Open transversalis fascia Hernia sac medial to the inferior epigastric vessels Hernia sac freed from inguinal ligament Medial: Sutures placed pubic tubercle through transversus abdominis to Cooper's ligament below lateral: Transition suture close femoral canal Relaxing incision: Anterior rectus sheath
94
treatment of fat emboli
immediate stabilization of fracture or long bones Decreases incident supportive management: May require intubation Not proven: Steroid in heparin
95
treatment of mesenteric obstruction and FAP patient with history of total domino proctocolectomy and ileoanal anastomosis
sulindac - anti-inflammatory medication decrease the size of desmoid tumor
96
LaPlace equation
tension = pressure x (radius / wall thickness)
97
2-year-old boy watery diarrhea, palpable mass on his right flank. elevated blood pressure and metanephrines in his urine. ataxia
nephroblastoma! The
98
poor prognosticators of nephroblastoma
age or than one Increasing neuron specific enolase LDH N-myc amplification
99
Findings that gives nephroblastoma better prognosis
hyperdilipoid more DNA within tumor more susceptible to chemotherapy
100
palliation of unresectable pancreatic cancer
at endoscopic or PERCUTANEOUS transhepatic stent Endoscopic BETTER results of your complications Percutaneous reserved for patients with technical issues with endoscopy metal stent longer lasting Gastric outlet obstruction-second portion of duodenum Duodenal obstruction-third or fourth portion and duodenum Biliary obstruction: Endoscopic expandable metal stent and duodenum Not able to stent-gastro J. pain refractory to narcotics: Endoscopic or percutaneous celiac plexus block
101
most common scenario her surgery is the approach taken to palliate pancreas cancer
undergoing laparotomy for anticipated resection and found to be unresectable
102
most accurate diagnosis for renovascular hypertension
angiography! Ultrasound is screening tool to assess flow velocities MRI made over diagnosis
103
indications for surgery of spontaneous pneumothorax
recurrence Persistent leak Incomplete expansion High risk-high-pressure environment including air travel
104
Berger disease
small and medium vessels Tobacco worsens Usual involves more than one digit Initial treatment tobacco cessation
105
ABI calculation and findings
ankle divided by brachial higher of the 2 sides used Dorsalis pedis and posterior tibial Normal 1.0 claudication 0.7-0.9 Rest pain 0.4-0.7 Wound complications and gangrene/tissue lost LESS than 0.4
106
cholangiocarcinoma risk factors, major prognosticator
primary sclerosing cholangitis margin status
107
treatment of cholangiocarcinoma
surgery only chance for cure NO chemotherapy
108
classification of cholangiocarcinoma
``` #1 involves common hepatic duct #2 hepatic bifurcation #3 secondary hepatic ducts on one side #4 tumors involved both side secondary hepatic ducts ```
109
medial pectoral nerve
supply of both pectoralis major and pectoralis minor
110
lateral pectoral nerve
supplies only pectoralis major pectoralis major more lateral
111
where anatomically does Zenker's diverticulum develop
posteriorly Transition zone between hypopharynx and esophagus-scalene triangle Weakness near the cricopharyngeus muscle because from failure relaxation of upper esophageal sphincter FALSE diverticulum
112
shortness of breath and dyspnea on exertion. A chest x-ray shows a small calcified lesion in the right upper lobe that is new from previous films. The patient reports that he was recently on a hiking trip in Ohio
histoplasmosis
113
treatment histoplasmosis
self limiting and do not require any further intervention! careful, observe but These patients can have bulky mediastinal nodes that can cause compressive symptoms.
114
course of the thoracic duct
originates at the cysterna chyli at L1-L2 courses superiorly on the RIGHT the AORTIC hiatus. right of midline until CROSSES to the left at T4-T5. empties in to the LEFT subclavian vein at the junction with the IJV careful, not brachiocephalic
115
surveillance Peutz-Jegher syndrome
colonoscopy every 2 years extracolonic cancers screening should begin at age 25 cervical and breast screening other extracolonic cancers: Thyroid Lung
116
timing of surgery for congenital diaphragmatic hernia
not emergent Plan for date 2-3 of life the neonate is free of significant respiratory and cardiovascular compromise
117
treatment of duodenal adenocarcinoma first or second portion of duodenum
Whipple resection no chemoradiation
118
Treatment of duodenal adenocarcinoma third or fourth portion of duodenum
segmental resection no chemoradiation
119
unstable patient esophageal perforation found to have cancer
cervical esophagostomy gastrostomy feeding J.
120
Gold standard for AV fistula access
radiocephalic wrist-Cimino anatomic snuffbox or just above the wrist crease
121
that study to workup colovesicular fistula
CT scan and demonstrate pneumaturia but also needs colon Endoscopy Cystoscopy
122
blood supply to the pancreas
celiac Superior mesenteric artery Splenic artery
123
when is carotid endarterectomy not indicated
less than 50% stenosis
124
indications for carotid endarterectomy
greater than 60% stenosis even asymptomatic
125
size of ileal resection consistent with vitamin B12 problem
60 cm
126
size ileal resection at risk for bile acid malabsorption
100 cm liver cannot compensate with increased hepatic symphysis the bile-fat is not bound with bile sufficiently causing steatorrhea
127
algorithm for workup of hemobilia
stable: Endoscopy rule out other causes of upper GI bleed Unstable high index of suspicion: Angiography therapeutic and diagnostic
128
Prior to dividing the gastrohepatic ligament at the right crus, what aberrant structure may be encountered
and accessory LEFT hepatic artery originating from the left gastric artery careful, right crus region may have a LEFT accessory hepatic artery
129
structures to be where of dissection around the right crus
LEFT vagus anterior L APR careful, right crus left anterior vagus LEFT accessory hepatic artery and
130
pyoderma gangrenosum
treatment steroids Improved with resection of inflamed bile Associated with inflammatory bowel disease
131
and primary bile salts are conjugated where and by what
hepatocytes GLYCINE Taurine
132
most common bacteria the colon
Bacteroides fragilis Other anaerobes: lactobacillus bifidus clostridium Eubacterium ``` Aerobe: Escherichia coli- most common AEROBE Klebsiella Proteus Enterobacter enterococcus-Streptococcus faecalis careful, ```
133
what helps platelet behind the endothelium
von Willebrand factor
134
What helps platelet aggregate
thromboxane A2 other affect is vasoconstriction
135
what cross-links platelets
thrombin converting fibrinogen to fibrin interval, cross-linking is not aggregation
136
major inflammation stimulator for atherosclerosis
lipid core made from LDL
137
at what point is compensatory arterial dilation no longer sufficient to compensate for percentage of stenosis from plaque
40% careful, exertional angina not seen total 75% stenosis
138
the role of Nissen fundoplication with Barrett's esophagus
better than trying to maximize medical therapy because there is continuation of reflux even if acid is controlled
139
relationship of aortic arch and a thoracic duct
thoracic duct runs posterior to the arch Originates at the cisterna chyli between T10 and L3 and enters the chest through the aortic hiatus to the right of the aorta and at T5, turns left and courses posterior to the aortic arch courses anterior to the vertebral bodies between the aorta and the azygos vein and posterior to the esophagus
140
mechanism of Cilostazol
Pletal This is a phosphodiesterase III inhibitor works on cAMP Acts to: inhibit smooth muscle so contraction and platelet aggregation
141
mechanism of action of Pentoxyfiline
increases blood cell look stability mechanism unknown used to treat claudication on
142
mechanism action of statin
HMG CoA reductase inhibitor
143
drugs that inhibit cyclooxygnease
ASA | nonsteroidal anti-inflammatories
144
mechanism of action of Plavix
irreversibly inhibited adenosine diphosphate ADP on platelet cell membrane
145
only FDA approved treatment for claudication by medication
Cilostazol phosphodiesterase 3 inhibitor - decrease smooth muscle/decreased platelet aggregation Pentoxyfinline - red blood cell flexibility
146
findings of esophageal scleroderma
low amplitude Simultaneous contractions Normal lower esophageal pressure careful, achalasia can have simultaneous contractions-difference is fail relaxation the lower esophageal sphincter
147
treatment of esophageal scleroderma
treat underlying scleroderma and secondary symptoms of esophagus improve methotrexate and immune modulaters
148
diagnoses test of choice for blunt aortic dissection
TPA
149
aortic Aneurysm of Marfan syndrome
aortic root! risk of dissection
150
defect in Ehlers-Danlos syndrome
collagen
151
treatment of immediate postop intracranial embolism after carotid endarterectomy
thrombolytics
152
inspiratory reserve volume
At the end of tidal volume inspiration it is the maximum volume that can be inhaled from there
153
expiratory reserve volume
from the end of title volume exhalation the maximum amount of air that can be exhailed from there
154
residual volume
volume air remaining in lungs after maximal exhalation | this includes a dead space
155
total lung capacity
volume in lungs after maximal inflation
156
inspiratory capacity
inspiratory reserve volume | AND tidal volume
157
functional residual capacity - definition and calculation
the volume in lungs after normal exhalation total lung capacity minus inspiratory capacity or expiratory reserve volume PLUS residual volume
158
vital capacity
total lung capacity minus residual volume
159
structures of the anterior compartment of the leg
extensor pollicis longus Extensor digitorum longus Tibialis anterior Peroneal tertius deep peroneal nerve ( careful, deep peroneal nerve not so deep - anterior compartment does not have tibial nerve) ANTERIOR tibial artery
160
nerve most commonly injured during lower extremity fasciotomy
superficial peroneal nerve Superficial is at risk with - lateral incision - lies near the septum located in the lateral compartment
161
described for compartment fasciotomy
medial and posterior incision to the tibia: decompresses superficial and deep posterior lateral incision: Intermuscular septum decompresses anterior and lateral compartments
162
defect with injury to superficial peroneal nerve
inability to evert foot most commonly injured nerve during fasciotomy-lateral compartment
163
defect was injury deep peroneal ulnar
FOOT DROP unusual to injure during fasciotomy
164
location of the deep peroneal nerve
ANTERIOR compartment most commonly compressed nerve and compartment syndrome
165
location and defect with tibial nerve
DEEP POSTERIOR compartment
166
nerve and vessel and deep posterior compartment
tibial nerve Posterior tibial artery (careful, deep peroneal nerve is ANTERIOR compartment)
167
most common organism for prosthetic graft infection
staph aureus | careful, no specific infection is staph epidermidis
168
relationship of right hepatic artery to the common hepatic duct
right hepatic artery passes posterior to common hepatic duct as it heads towards the liver 85% of the time
169
relationship of right replaced hepatic artery
to portal triad and medial aspect of Calot's triangle POSTERIOR to CYSTIC duct
170
first location of metastasis in the invasive gallbladder cancer
or cystic duct lymph nodes
171
largest resistance and drop in blood pressure change of any vessel
arteriols careful, not capillaries that are downstream - because surface area is so large and extensive network branching
172
hereditary non-polyposis colon cancer special tumor characteristics
microsatellite instability MLH1 MSH2 genes - these cause the: DNA mismatch repair
173
Amsterdam criteria
3 or more first degree relatives colon cancer Across 2 generations One member diagnosed prior to the age of 50
174
associated with Lynch I
colon cancer
175
associated with Lynch II
Cancer of : endometrial Ovarian Gastric
176
origin of the internal thoracic artery
first branch off subclavian
177
tissue supplied by internal thoracic artery
``` chest wall Breast Branches to Thymus Mediastinum The sternum ```
178
course of the internal thoracic artery
first branch off subclavian Between the internal oblique and transverse thoracic muscles Bifurcated sixth intercostal space Muscular phrenic Superior epigastric artery explanation mark
179
cranial nerve innervated carotid body
cranial nerve 9 Branch of glossopharyngeal
180
physiologic mechanism and responsive carotid body
edema receptor Paraganglioma ``` Stimulated by: Hypercapnia Hypoxia Decrease pH Increase temperature Signs none Nicotine ``` ``` action: Sympathetic stimulation Increased heart rate Increased vascular tone Intracerebral cortical activity ```
181
what do hepatocytes produced
bile Synthesis proteins Synthesis glucose
182
Space of Disse
interaction between hepatocyte and blood substances are exchanged via active transport
183
recommended treatment for posterior knee dislocation and no flow past proximal popliteal artery on angiogram
bypass with CONTRALATERAL reverse saphenous vein
184
the gallbladder his mechanism of bile concentration
ATPase dependent sodium chloride transport
185
treatment of 2 cm common iliac occlusion
angioplasty and stent procedure of choice for all common iliac stenoses less than 3 cm
186
most common time period to develop aorto enteric fistula
2-6 years
187
diagnostic modality that best demonstrates chance of cure and squamous cell carcinoma of the esophagus
EUS EUS is better than PET
188
most important prognosticators for esophageal cancer
depth of tumor penetration and node involvement
189
indications on EUS the esophageal cancer his resectable
not invaded adjacent organs Fewer than 5 enlarged lymph nodes
190
when should screening begin with HNPCC
colonoscopy age 20 and all polyps removed
191
recommend surgery for HNPCC colon cancer
total bowel colectomy with ileorectal anastomosis or female in no longer childbearing: total abdominal hysterectomy and salpinco-oophorectomy careful, FAP surgery is total abdominal proctocolectomy with ileal anal J-pouch
192
extent of colon resection for cancer proximal to the hepatic flexure
right hemicolectomy: Resect ileum approximately 5 cm proximal to the ileocecal valve anastomosis to the first third of the transverse colon take the right branch of the middle colic artery also takes: Ileocolic Right colic
193
mechanism action of pancreatic polypeptide
suppress: bile secretion gallbladder contraction exocrine pancreatic function
194
treatment of superior vena cava syndrome from multiple tunneled hemodialysis catheters
balloon angioplasty - first choice ( NOT embolectomy thrombectomy) Often requires multiple interventions Stents for now been tried - with some success
195
percentage of gallstone ileus as the cause in an obstruction in patient older than 70 With no previous surgery and no hernias on exam
up to 25%!
196
most common site of fistula and most common site of obstruction from gallstone ileus
duodenum terminal ileum-most narrow
197
epiphrenic diverticulum
pulsion diverticulum distal esophagus does not contain all layers of esophageal wall
198
traction diverticulum
all layers of esophageal wall midesophagus
199
post thrombotic syndrome
23-60% of deep venous thrombosis ``` edema Pigmentation Calf muscle dysfunction Venous stasis ulcer Valvular incompetence Chronic venous insufficiency ```
200
fibromuscular dysplasia pathophysiology and most common site of recurrence
most common site renal artery 80% females 40-50-year-old Medium-size arteries MEDIAL most common other less common sites: Carotid artery Iliac artery Vertebral artery
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primary treatment of sliding hernia
type I hernia PPI
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List order of prevalent of hiatal hernia
type I #1 most common careful, type III SECOND most common type II third most common
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structures at risk when dissecting posterior hiatal hernia sac in the mediastinum
left anterior vagus nerve | pleura, esophagus, and inferior pulmonary veins
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treatment of acute cholecystitis in patients who are too high a risk to undergo surgery including child's C.
transit hepatic cholecystostomy even in child C.
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where is the swallowing Center located
Medulla same as breathing center
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risk of major limb amputation in patient with intermittent claudication per year
1% per year
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Severity of stenosis is categorized according duplex ultrasound
Less than 20% stenosis (NORMAL): - Velocities: 150 cm/sec - Waveform Characteristics: Spectral broadening throughout systole with no change in waveform - Management: Rescan in 6 months 50% to 75% stenosis (MODERATE): - Velocities: >180 cm/sec - Waveform Characteristics: severe spectral broadening in systole with reversed-flow components - Management: Rescan in 4-6 weeks; if lesion does not progress during two cycles of testing, increase scan interval to 3 months Greater than 75% stenosis (SEVERE): - Velocities: >300 cm/sec - Waveform Characteristics: severe lumen reduction with a "flow jet"; damped distal velocity waveform - Management: Recommend repair (urgent if average PSV 0.15)
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primary functional bile acids
digestion of fat
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where are bile acid conjugated
hepatocyte: Glycine Taurine Colon: Bacteria conjugate primary bile acid into: deoxycholic acid lithocolic acid
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enzyme responsible conjugate primary bile acid
Glucoronyl transferase
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non gallstone reasons to perform cholecystectomy
``` hydrops - Cystic duct obstruction Biliary dyskinesia porcelain gallbladder ( but less concerned than patch were calcification) ``` NOT ascending cholangitis
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when do you start upper scope screening patients with FAP
age 20-25 OR When colonic polyps first appear
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76-year-old female presents on post operative day #14 from a left femoral-popliteal bypass graft with PTFE with acute left lower extremity pain. You suspect that the graft has thrombosed. Which is the MOST appropriate treatment for this patient?
Thrombectomy with intra operative angiogram
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RCC that extends into the IVC
can be pulled out during the radical nephrectomy.
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AAA renal dysfunction perioperatively increased in
26-42% incidence supraceliac clamping Increased age preoperative hypotension prolonged clamp time
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described anatomy of right renal artery
medially below SMA L2 longer than the left as it courses POSTERIOR to inferior vena cava posterior to renal vein 25-30% have accessory renal arteries
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surgical exposure required to access right renal artery
Kocher maneuver | Take down the right colon
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pigmentation pigmentation of bile
bilirubin diglucuronate | conjugated form
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primary source of bilirubin
``` senescent red blood cells breakdown of heme heme is converted to: biliverdin biliverdin is converted to: bilirubin bilirubin is taken up by hepatocyte: conjugated by glucuronic acid ```
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what gave his stool bile color
URObilinogen this is because he did bilirubin from bacteria - and the amount not reabsorbed is passed in the stool
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effect of nitric oxide on platelet irrigation
INHIBITS aggregation careful, vasodilation major factor ``` in also: Decreases inflammatory response decreases: VACAM - 1 ICAM - 1 MCP - 1 ```
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list the order of splenic aneurysms
splenic 60% hepatic 20% SMA 5.5% celiac 4%
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treatment of pseudoaneurysm common femoral artery
greater than 2 cm: Thrombin injection ``` open repair: greater than 5 cm with wide neck Overlying skin necrosis distal ischemia Nerve compression active bleeding ```
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most common postoperative swelling of lower extremity bypass for chronic ischemia
lymphedema generally improves over 2-4 months
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most common bacteria to cause lymphangitis and upper extremity
Streptococcus pyogenes careful, other cause: Staph aureus
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treatment of the iliac and femoral DVT in patient with swelling and extreme pain
thrombolysis - catheter directed
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superior mesenteric artery syndrome treatment
chronic: duodenojejunostomy not arterial bypass Less common surgical treatments for SMA syndrome include Roux-en-Y duodenojejunostomy, gastrojejunostomy, anterior transposition of the third portion of the duodenum, intestinal derotation, and division of the ligament of Treitz. acute: Medical management Pro-motility agents such as metoclopramide may also be beneficial
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etiology of superior mesenteric artery syndrome
compression of the third portion of duodenum between superior mesenteric artery and perivertebral musculature/vertebrae If conservative treatment fails when reversed peristalsis persists,
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Factors that decrease the risk of PAD
HDL, nitrous oxide prostacyclins
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What is the MOST likely organism to be associated with a non-aneurysmal aortic infection
Salmonella careful, STAPH is most common when associated with aneurysm careful, STREP is most common when infection is to do bacterial endocarditis
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Most likely location for non-aneurysmal aortic infection
suprarenal
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postoperative intervention that had the most influence on vein graft patency
duplex ultrasound- improved patency by 15% when compared to clinical examination Careful, Plavix is used not definitively proven for end result patency
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treatment of phlegmasia cerulea dolens
catheter directed thrombolytic can improve her outcome The alternative for this condition is surgical venous thrombectomy. No matter which treatment is chosen, long-term anticoagulation is indicated. Careful, thrombectomy and systemic umbilicus have poor results
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Presentation of phlegmasia cerulea dolens
``` complication and DVT- arterial inflow can be compromised Complete occlusion of the venous system venous gangrene can develop unless flow is restored. edema and blistering with cyanosis ``` occasionally involve the trunk colon
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symptoms of vertebral artery stenosis
``` dizziness Vertigo Tendinitis Dysphagia Dysarthria Ataxia ```
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indications for treatment or vertebral artery stenosis
symptoms
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lymphedema precox
primary lymphedema Occurs after puberty
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Lymphedema tarda
primary lymphedema Recurred in women after the age of 35
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relationship of nitric oxide to LDL
nitric oxide inhibitor of LDL
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history of MI is what kind of perioperative risk
intermediate!
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physical diagnosis of Steal syndrome AV fistula
compressed graft relieve symptoms and returns radial pulse
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size of popliteal aneurysm requiring surgery
2.5 cm or greater - 30% symptoms in 3 years ligate aneurysm as well the bypass
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strong risk risk factor for AAA
smoking other risk factors: MMP - damage to media and elastin hypertension-infrarenal age - decreased the last and
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Layer affected in AAA
tunica MEDIA
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presentation of occlusion of superficial femoral artery
thigh is still vascularized due to patent femoral profundus! discoloration of the knee and distally
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presentation of occlusion of the common femoral artery
cool lower extremity from 5 distally May have waterhammer pulse or no pulse