Mock 11

Question 1

MOA disulfiram

Answer 1

non competitive antag ald dehydrogenase

Question 2

pimozide side effect leading to restriction

Answer 2

qtc pronong

Question 3

vigabatrin side effect that needs monitoring

Answer 3

visual field loss

Question 4

proteins in FTD

Answer 4

tau
ubiquitin

Question 5

lateral n of hypothal

Answer 5

orexin (lateral, wide, fat)

Question 6

paraventricular n of hypothal

Answer 6

corticotrophin RH

paraventricular - beside ventricle
adrenal - beside kidney

Question 7

buspirone moa

Answer 7

5ht1a partialagonist

Question 8

mirtazapine moa

Answer 8

alpha 2 antag
5-ht2a +c antag
h1 antag

Question 9

agomelatine moa

Answer 9

MT1+2
antag at 5HT2C + B

Question 10

LBD chromosomal location

Answer 10

ApoE chr 19

Question 11

Mahler

Answer 11

1. autism 0-2m - own world, sleep ++
2. symbiosis 2-5 m - mum and baby one entity develop perception abilities
3. Differentiation/Hatching 5-10 m - increased alertness. Attention to outside world.
4. Practicing 10-18m - ability to move autonomously increases exploration
5. Rapprochment 18-24m -realise own helplessness. Need for independence alternates with closeness. Moves away from mother but returns for comfort.
6. Object constancy 2-5 y - appreciates constancy of people.

Question 12

selective attn test?

Answer 12

stroop

Question 13

sensitive to rebuffs PD

Answer 13

paranoid (think others are exploiting/harming/deceiving)

Question 14

categories of depression with psychotic features

Answer 14

mod and sev

Question 15

wing beating tremor

Answer 15

wilsons

Question 16

laxative purge resultant biochemical disorder

Answer 16

metacidosis

Question 17

bedside screen for cognitive impairment

Answer 17

MOCA

Question 18

camerons FTD

Answer 18

asyndesis

Question 19

which schneider for FTD?

Answer 19

CARL

Question 20

internal salience?

Answer 20

self motivated desire for action/object

Question 21

attention achieves what

Answer 21

sensory to STM

Question 22

2 year old boy tries to run, falls, cries. Which Erikson?

Answer 22

autonomy vs shame
unable to be indep hence cry
18-36m

initiative vs guilt is 3-5 year and is more to do with ability to affect environment

Question 23

which piaget for peekaboo?

Answer 23

sensorimotor

Question 24

what age for sensorimotor?

Answer 24

0-2 years

Question 25

worst antidep for QTc

Answer 25

citalopram, dose related

Question 26

DAWS

Answer 26

anxiety depression irritability orthostatic hypotension perspiration

Question 27

weight gain with antipsychotics

Answer 27

more sig in children

Question 28

vortioxetine MOa

Answer 28

SERT inhib agon 5ht1 antag 5ht3 and 7

Question 29

longest half life depot

Answer 29

paliperidone and aripiprazole pali available as 3m

Question 30

TCAs overdose what cardiac effect?

Answer 30

tachycardia with VT

Question 31

TCA OD kinetics?

Answer 31

zero (once saturated)

Question 32

cloz agran risk

Answer 32

0.01%

Question 33

least likely to induce manic switch?

Answer 33

sertraline (the GOAT)

Question 34

disulfiram SE without etoh

Answer 34

headache

Question 35

non-fluent expressive dysphasia which dementia?

Answer 35

FTD (brocas)

Question 36

apoe4 RR

Answer 36

3x for heterozgyote 8x for homo

Question 37

thymidine deprivation model for research?

Answer 37

fragile X

Question 38

behavioural syndrome in frag x

Answer 38

shyness gaze avoidance (autistic phenotype)

Question 39

endophenotypes, who?

Answer 39

gottesman

Question 40

cholecytokinin which disorder has been studied

Answer 40

bulimia

Question 41

AMPA vs NMDA

Answer 41

AMPA fast excitatory (amped up) NMDA plasticity and learning (2 ligands D for dual ligand)