modified block 12 Flashcards

(47 cards)

1
Q

the coventional AH pathways is also called

A

corneoscleral

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2
Q

main structures in the conventional AH pathway

A

TM and SC

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3
Q

which AH pathway is IOP dependent

A

conventional path

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4
Q

the unconventional AH pathway is also called

A

uveoscleral

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5
Q

main structure in the unconventional path

A

ciliary muscle bundle

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6
Q

which AH pathway is IOP independent

A

unconventional path

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7
Q

what are 3 big factors that affect IOP

A
  • peak in morning
  • corneal thickness
  • steroids
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8
Q

if a cornea is thicker than normal, how will the IOP be affected

A

abnormally high reading

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9
Q

2 ways to obstruct outflow

A
  • occlusive angle

- injury to TM

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10
Q

what are possible causes of an occlusive angle (5)

A
  • severe diabetes
  • uveitis
  • hyphema
  • pseudoexfoliative glaucoma
  • pigment dispersion glaucoma
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11
Q

what are possible causes of injury to TM (2)

A
  • fuch’s heterochromic iritis

- glaucomatocyclitic crisis

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12
Q

an acute rise in EVP result in what

A

1:1 ratio of increase IOP

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13
Q

4 main aging changes to the anterior chamber

A
  • reduced depth
  • reduced uveoscleral outflow
  • extracellular matrix plaque in TM
  • increased outflow resistance in the TM and SC
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14
Q

what has a big effect on the anterior chamber depth

A

cortical cataract

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15
Q

whey is there a reduction in uveoscleral outflow with age

A

increase in the amount of connective tissue in ciliary muscle

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16
Q

5 components of vitreous

A
  • water
  • collagen
  • hyaluronic acid
  • vitreal cells
  • vitamin C
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17
Q

what makes up 99% of the vitreous

A

water

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18
Q

what 2 components give vitreous the gel like texture

A

collagen interacting with hyaluronic acid

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19
Q

4 major functions of the vitreous

A
  • support
  • diffuse barrier
  • metabolic buffer
  • transparency
20
Q

what can affect the “support” function of the vitreous

A

PVD

also macular edema

21
Q

what can affect the “ metabolic buffere” function of the vitreous

A
  • reduce neovascularization in retina
  • neovascular galucoma
  • NSC
22
Q

what can affect the “ transparency” function of the vitreous

A
  • synchisis scintillation

- asteroid hyalosis

23
Q

accumulation of choesterol within vitreous

A

synchisis scintillations

24
Q

accumulation of calcium within vitreous

A

asteroid hyalosis

25
the "metabolic buffer" function of the vitreous: it is a reservoir for what
- vitamin C - potassium - glucose/glycogen
26
what happens to the vitreous with age
it becomes more liquified
27
the breakdown of the vitreous gel and aggregation of collagen due to increase of liquid portion
vitreous syneresis
28
what is the msot common cause of PVD
vitreous syneresis
29
what is a floater
aggregation of collagen
30
change of gel structure most likely occur in what part of the vitreous
center
31
what are the 3 layers of TF (from cornea to air)
mucus layer aqueous layer lipid layer
32
Composition of: mucus layer
Mucin
33
Composition of: lipid layer
Meibomian oil
34
Composition of: aqueous layer
- water (mainly) - Na and Cl (osmolarity) - K and Ca (corneal epithelium health) - Protein
35
Function of: mucus layer
- provide medium for aqueous layer - cover epithelium - trap debris and bacteria
36
Function of: aqueous layer
- provide protection - buffering - regulate cornea epithelium proliferation
37
Function of: lipid layer
Slow the evaporation of aqueous layer
38
Source of: mucus layer
- primary: goblet cells | - squamous cells of cornea and conj
39
Source of: aqueous layer
- main lacrimal gland | - accessory lacrimal gland
40
Source of: lipid layer
- primary: meibomian gland | - zeis and moll
41
Tests for tear secretion (4)
- schirmer 1 - schirmer 2 - phenol red thread test - meinscometry
42
Tests for tear film stability (4)
- TBUT - ocular protection index - videokeratography - tear turnover
43
Tests for tear film osmolarity (3)
- tear film osmolarity - tear Ferning - tear evaporation
44
Tests for lipid layer evaluation (2)
- interferometry | - meibometry
45
Tests for ocular surface evaluation (3)
- fluorescein - Rosa bengal - lissamine green
46
Secreted by the corneal epithelium | - helps mucus layer stay stable on the corneal epi
Glycocalyx
47
Aging changes of the lacrimal system (5)
- dec in goblet cells - reduced tear reflex secretion - change in composition of meibomian secretion - increase of plugged meibomian - reduced lacrimal drainage