Modul 16 pt 2 Flashcards

(53 cards)

1
Q

What is the term used for blood flowing through body tissues?

A

Tissue Perfusion

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2
Q

What is the purpose of Tissue perfusion?

A

Delivery of Oxygen and nutrients

& the removal of CO2 and metabolic waste

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3
Q

Blood flow is also really important in what three functions?

A

Gas exchange in lungs
Nutrient absorption in GI tract
Urine formation in Kidneys

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4
Q

What is the term used for automatic blood flow to each tissue in proportion to its requirement at any given time?

A

Autoregulation

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5
Q

What does autoregulation do?

A

Changes arterial diameters

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6
Q

What are two types of short termed auto-regulation of tissue perfusion?

A

Myogenic control

Metabolic control

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7
Q

The vasodilation of arterioles and relaxation of pre capillary sphincters during decline of O2 and substances in metabolic active tissue

A

Metabolic Control

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8
Q

What is the major factor in Metabolic control that causes vasodilation?

A

NO (nitric oxide)

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9
Q

This is the most potent vasoconstrictor known that aids in metabolic control

A

Endothelins

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10
Q

This short term control is responses of smooth muscle that keeps tissue perfusion constant despite tissue pressure

A

Myogenic control

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11
Q

How does the myogenic control keep pressure constant?

A

Passive stretch

Reduced stretch

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12
Q

Vasoconstriction in metabolic situations is due to sympathetic ______ and ________.

A

Stimulation

Endothelins

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13
Q

How does passive stretch promote increased tone and vasoconstriction?

A

It is increased intravascular pressure

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14
Q

What does reduced stretch promote?

A

Vasodilation that increases blood flow to tissues

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15
Q

What is a long-term regulation that occurs when short-term regulation cannot meet tissue nurtrient requirements?

A

Angiogenesis

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16
Q

What does angiogenesis do?

A

Increases the number of vessels in a certain area and increases existing vessels to enlarge

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17
Q

Where is angiogensis common?

A

In the heart when a coronary vessel is occluded (blocked)

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18
Q

What short term regulation dominates in skeletal muscle?

A

Myogenic

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19
Q

During muscle activity, blood flow increases in direct proportion to the ______

A

exercise or metabolic activity

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20
Q

Blood flow to the brain is _____ as neurons are intolerant of ischemia (restriction of blood supply to vessels)

A

Constant

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21
Q

What are the main metabolic controls of the brain?

A

Decline of pH

increased CO2 or Vasodilation

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22
Q

What are the Myogenic controls of the brain?

A

Decrease and Increase in MAP

causes cerebral vessels to constrict and dilate

23
Q

The brain is vunerable under extreme ____ pressure changes

24
Q

What are the three reasons blood flow to the skin is important

A

Maintain body temp
Blood reservoir
Supplies nutrients to cells

25
What is the blood flow to the skin controlled by?
Sympathetic nervous system
26
When the body temp rises, what are the main three things that happen?
Heat radiates from skin Sweat causes vasodilation Release of NO
27
Why is the pulmonary circulation unusual?
Pathway is short | Arterial resistance and pressure are low
28
What organ is the auto regulatory mechanism the opposite of that of most tissues?
Lungs
29
What do low and high levels of O2 cause for the lungs?
high- vasodilation | low- vasoconstriction
30
During ventricular Systole in the heart, coronary vessels are _______
Compressed
31
During ventricular Systole in the heart, myocardial blood flow _____
Ceases
32
During ventricular Systole in the heart, stored myoglobin supplies
Enough Oxygen
33
During strenuous exercise, how much does the blood flow increase?
three to four times
34
During blood flow through capillaries this is most common
Vasomotion
35
In capillary gas and nutrient exchange, what goes from blood to tissue?
O2 and Nutrients
36
In capillary gas and nutrient exchange, what goes from tissue to blood?
CO2 and Waste
37
In capillary gas and nutrient exchange, Lipid-soluable molecules diffuse directly through ______ ______.
Endothelial membranes
38
In capillary gas and nutrient exchange, water-soluable pass through ______ and _______
clefts and fenestrations
39
In capillary gas and nutrient exchange, Larger molecules such as protein as transported by
Pinocytotic vesicles or caveolae
40
This is extremely important in determining relative fluid volumes in the blood and interstitial space
Bulk Movements
41
What does bulk flow depend on?
Two opposing forces Hydrostatic pressure Colloid osmotic pressure
42
Hydrostatic pressue is made up of two distinct pressure that act against eachother, these pressures are
Capillary hydrostatic pressure | Interstitial fluid hydrostatic pressure
43
In Capillary hydrostatic pressure, where is fluid forced?
through Capillary walls
44
Where is pressure greater and less in Capillary hydrostatic pressure?
Greater at arterial end | Less at venule end
45
Why is Interstitial fluid hydrostatic pressure usually assumed to be zero?
Lymphatic vessels
46
Colloid osmotic pressure is created by nondiffusible ________ _______ that draw water towards themselves
plasma proteins
47
This comprises of all the forces acting on a capillary bed
Net Filtration Pressure
48
What forces dominate at the arterial end?
Hydrostatic forces
49
What forces dominate at the venous end?
Osmotic Forces dominate
50
What is circulatory shock resulted by?
inadequate blood flow to meet tissue needs
51
This circulatory shock that results from large-scale blood loss
Hypovolemic shock
52
This circulatory shock results from extreme vasodilation and decreased peripheral resistance
Vascular Shock
53
This circulatory shock results when an inefficient heart cannot sustain adequate circulation
Cardiogenic shock