Module 2 Flashcards

(55 cards)

1
Q

Plasma Membrane

A

A lipid bilayer which forms the external boundary of a cytoplasm of a cell

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2
Q

Function of Plasma Membrane

A
  • Isolation
  • Controlling entry and exit of materials
  • Sensitivity to the Environment
  • Support
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3
Q

Plasma Membrane’s Structural Features

A
  • Membrane Lipids
  • Membrane Proteins
  • Membrane Carbohydrates
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4
Q

Membrane Lipids

A

Lipids form a double-layered surface the plasma membrane

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5
Q

Membrane Proteins

A

A protein molecule that is attached to, or associated with, the membrane of a cell

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6
Q

Membrane Proteins: Integral

A

Cannot be easily operated from plasma membrane without damaging or destroying it

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7
Q

Membrane Proteins: Peripheral

A

Bound to the inner/outer surface of the membrane and are easily separated from it

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8
Q

Membrane Carbohydrates: Lubrication and Protection

A

The glycoproteins and glycolipids from a thick and sticky layer that lubricates and protects the plasma membrane

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9
Q

Membrane Carbohydrates: Anchoring and Locomotion

A

Due to it’s components being sticky, the glycocalyx can help anchor the cell in place

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10
Q

Membrane Carbohydrates: Specificity in Binding

A

Glycoproteins and glycolipids can function as receptors, binding specific extracellular compounds

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11
Q

Membrane Carbohydrates: Recognition

A

Cells involved with the immune response recognise glycoproteins and glycolipids as normal or abnormal.

The body recognises it’s own glycoproteins and glycolipids as “self” rather than “foreign”.

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12
Q

Organelles of a Cell

A
  • Non-membranous Organelles
  • Organelles (“little organs”)
  • Cytoskeleton
  • Microvilli
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13
Q

Organelles of a Cell: Non-membranous Organelles

A

Not completely enclosed by membranes and do not have a definite boundary

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14
Q

Organelles of a Cell: Membranous

A

Isolated from the cytosol by phospholipid membranes, just as the plasma membrane isolates the cytosol from the extracellular fluid

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15
Q

Organelles of a Cell: Organelles (“little organs”)

A

Internal structures of cells that perform most of the tasks that keep a cell alive and functioning

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16
Q

Organelles of a Cell: Cytoskeleton

A

Serves as the cell’s skeleton — an internal protein framework that gives the cytosol strength and flexibility

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17
Q

Organelles of a Cell: Microvilli

A

Small, finger-like membrane protrusions of the plasma membrane that increase the surface area exposed to the extracellular environment

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18
Q

Nucleus

A
  • The largest and most visible structure in a cell

- Contains a supportive nuclear matrix

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19
Q

Genetic Coding

A

A triplet code - a sequence of three nitrogenous bases specifies the identity/translates into a single amino acid = building blocks of proteins

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20
Q

Proteins Synthesis

A

The process where biological cells generate new proteins from amino acid “building blocks” — balanced by the loss of cellular proteins via degradation/export

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21
Q

Transcription

A

The transfer of genetic instructions in DNA to mRNA from the nucleus to the cytoplasm, which is used as a template for the instructions to make protein

The process by which DNA is copied to RNA is called transcription

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22
Q

Translation

A

The instructions in mRNA are read, and tRNA brings the correct sequence of amino acids to the ribosome

RNA is used to produce proteins is called translation

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23
Q

Cell Structure

A

Semi-permeable membrane, a nucleus and cytoplasm

24
Q

Cellular/facilitated Diffusion

A

Molecules move across the plasma membrane from an area where they are at a higher concentration to areas where they are at a lower concentration until equilibrium is reached

25
Leak Channels
Passive channels that allow ions across the plasma membrane
26
Osmosis
Flow of water across a selectively permeable membrane
27
Osmotic Pressure
The force of water movement into that solution resulting from its solute concentration
28
Hydrostatic Pressure
Can oppose osmotic pressure; it is the pressure that any fluid in a confined space exerts
29
Hemolysis
Breakdown or destruction of red blood cells
30
Carrier-mediated Transport
Involves the binding and transporting of specific ions by integral proteins
31
Carrier-mediated Transport: Uniport
Moves molecules across the membrane independent of other molecules
32
Carrier-mediated Transport: Uniport
Moves molecules across the membrane independent of other molecules
33
Carrier-mediated Transport: Symport (cotransport)
Moves two substances in the same direction
34
Carrier-mediated Transport: Antiport (counter-transport)
Moves them in opposite directions
35
Primary Active Transport
Directly uses a source of chemical energy (e.g., ATP) to move molecules across a membrane — are not dependent on concentration gradients
36
Secondary Active Transport (cotransport)
A molecule is moved down its electrochemical gradient as another is moved up its concentration gradient
37
Significance of the membrane potential
The potential difference, measured in volts, between the two sides of a plasma membrane is a membrane potential
38
Cell Division
Reproduction of cels
39
Apoptosis
Genetically controlled death of cells
40
Mitosis
Nuclear division of somatic cells
41
Cytokinesis
Cytoplasm is divided to form two daughter cells and cell division ends
42
Interphase
A cell performs all its normal functions and if necessary, prepares for cell division — a non-dividing state — G₀ phase
43
Mitosis: Prophase
The chromosomes, which had been thin and threadlike in interphase, begin to condense,/thicken. Pairs of centrioles move to opposite sides of the nucleus Spindle fibres begin to form a bridge between the ends of the cell.
44
Mitosis: Metaphase
The spindle fibres attach to the centromeres of the chromosomes and line up the chromosomes along the centre, or “equator,” of the cell
45
Mitosis: Anaphase
The centromere of each chromosome divides in two, and the sister chromatids separate. The spindle fibres then pull the sister chromatids away from each other and toward opposite poles of the cell
46
Mitosis: Telophase
The cell is nearly done dividing, and it starts to re-establish its normal structures as cytokinesis (division of the cell contents) takes place
47
Cytokinesis
The cell physically splits into two daughter cells
48
Cell Life Cycle Regulation
An important internal trigger is the level of M-phase promoting factors (MPF) also known as maturation-promoting factor
49
Cell division and Cancer
Produced by abnormal cell growth and division, a tumour or neoplasm can be benign or malignant
50
Mutagens
Agents that cause a mutation are called mutagens Biological, physical or chemical agent that permanently changes genetic material, usually DNA — many mutations can cause cancer
51
Causes of Mutagens
Radioactive elements, X-rays, ultraviolet radiation, chemicals, intercalating agents, metals, transposon, virus, and bacteria can cause mutations
52
Carcinogens
An agent with the capacity to cause cancer in humans — results in formation of tumours or cancer
53
Causes of Carcinogens
Smoking, pathogens, radiation, environmental hazard, and diet can cause cancers
54
Cellular Differentiation
Inactivation of a particular genes in different cells, producing populations of cells with limited capabilities
55
Cellular Respiration
The biochemical process of converting fuel into energy and nutrients