Module 2 Flashcards
(38 cards)
does have iron
ferroprotoporphyrin
don’t have iron
protoporphyrin 9
2 identical pairs
globin chains
alpha and zeta chains : ___ amino acids
141
beta and gamma chains : ___ amino acids
146
unknown number of amino acids
theta
4 heme group attached to 4 globin chains
tetrameric molecule
forms cleft-pocket for hem
quaternary structure
uroporphyrinogen iii to coproporphyrinogen iii by the action of
uroporphyrinogen decarboxylase
alpha and zeta in short arm of
chromosome 16
gamma, beta, delta, epsilon in short arm of
chromosome 11
came from the common myeloid progenitor lineage
erythrocyte
days proliferation & maturation of precursors
6-7
days reticulocyte maturation
2-3
3 phases of an erythrocyte’s life
-Erythrocyte production
-Bone marrow release to the circulation
-Destruction or cell death
number RBCs produced from a single Pronormoblast
8-32
Production of ___reticulocytes from each pronormoblast
16
3 phases of development pathway in RBC
-Ribosome synthesis
-Hgb accumulation
-Ejection of nucleus
Single, most useful test to check or analyze if there’s anemia.
reticulocyte test
chromatin is distributed irregularly throughout the cytoplasm
karyorrhexis
basophilic nuclear remnants or clusters of DNA in the circulating erythrocytes.
Howell-jolly bodies
It has a detectable hemoglobin synthesis
prorubriblast
this is the last stage that undergo mitosis
rubricyte
Totality of all stages of erythrocytes, including precursor cells in the bone marrow and mature cells in the peripheral blood within vascular areas of specific organs
erythron
