MODULE 2 (SET B) Flashcards
(56 cards)
Each individual molecule in the complex
subunits
large complex protein that carries oxygen from our lungs, through our blood, to the cells in our body
hemoglobin
hemoglobin is made up of ______________________ that bind together
four subunit proteins
hemoglobin consists of protein subunits
globin molecules
smaller molecule or atom that binds to a larger molecule
ligand
TRUE OR FALSE: When oxygen binds to hemoglobin, the oxygen is considered ligand.
TRUE
TRUE OR FALSE: The binding of O2 to the heme changes the whole structure of hemoglobin.
TRUE
Two major conformations of hemoglobin/ states of hemoglobin
T-state and R-state
studies how molecules move around within cells and how molecules move from outside a cell to inside a cell and vice versa
Diffusion and Molecular Transport
process of molecules spreading out, as a result of random motion
Diffusion
Molecules move from a region of ___________________________
higher concentration to lower concentration
studying ligand binding seek to measure and understand
forces and energy;
interaction between multiple binding sites;
how changes to the molecules affect binding;
relationship between binding and conformational transition;
relationship between binding and biological function;
competition between the different ligands; rate at which binding occurs
primary means of molecules moving around within a cell
Diffusion
movement of substances like ions, atoms, and molecules from an area of their higher concentration to lower concentration without the involvement of any other molecules like a carrier protein
Simple Diffusion
It is a natural phenomenon where the particles move along a concentration gradient in a solution through a semipermeable membrane to attain equilibrium on both sides
Simple Diffusion
passive transport and no energy expenditure
Simple Diffusion
cannot be inhibited by an inhibitor molecule because of the absence of carrier proteins
Simple Diffusion
non-specific to any particle
Simple Diffusion
slow process
Simple Diffusion
Examples of Simple Diffusion
Gas Exchange; Absorption of Nutrients
a type of diffusion occurring in living cells where the molecules move from the region of their higher concentration to lower concentration guided by a helper protein molecule
Facilitated Diffusion
Usually an integral membrane protein that forms a pore or channel in the cell membrane
helper protein
passive transport mechanism and requires no energy
Facilitated Diffusion
spontaneous process in which charged ions or molecules are transported across the lipid-based cell membrane via a carrier transmembrane protein molecule
Facilitated Diffusion
