Module 3 Flashcards

1
Q

what are amino acids building blocks of ?

A

proteins

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2
Q

do all organisms use the same pool of amino acids to build their proteins

A

yes

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3
Q

what are the distinct advantages of creating biomolecules as polymers of smaller, simpler building blocks (3)

A
  1. simplicity of chemistry
  2. recycling
  3. diversity
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4
Q

what’re the common features of amino acids ? (4)

A

hydrogen
central alpha carbon
amino group
carboxyl group

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5
Q

which amino acid doesn’t have a chiral centre?

A

glycine

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6
Q

are proteins made from L or D isomers

A

L

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7
Q

what are the non polar amino acids (7)

A

G,A,V,L,I,P,M

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8
Q

what is phosphorylation?

A

a mechanism to regulate protein function

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9
Q

what are the aromatic amino acids ? (3)

A

Y,F,W

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10
Q

what’s an example of post transitional modification

A

phosphorylation

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11
Q

what can two cysteines form?

A

a covalent linkage called a disulfide bond

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12
Q

what do disulfide bonds do

A

stabilize protein structures

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13
Q

what does more cysteine mean for structure?

A

more rigid structures

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14
Q

what are the positively charged amino acids?

A

lysine (Lys, K)
arginine (Arg, R)
sometimes Histidine (His, H)

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15
Q

what are the negatively charged amino acids?

A

Aspartate (Asp, D)
Glutamate (Glu, E)

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16
Q

what do all amino acids have?

A

alpha carbon
carboxyl group
amino group

17
Q

how many buffering regions do diuretics have ?

A

Two

18
Q

how many buffering regions does a triprotic have ?

A

3

19
Q

what do triprotic amino acids have?

A

ionizable groups in their side chains

20
Q

What are the triprotic amino acids? (7)

A

Lys
Arg
His
Asp
Glu
Cys
Tyr

21
Q

What is it when pH is below pKa?

A

Protonated

22
Q

what is it when pH is above pKa?

A

unprotonated

23
Q

What is carboxyl in its protonated form?

A

COOH

24
Q

what is carboxyl in its unprotonated form?

A

COO-

25
Q

what is the amino group in its protonated form?

A

NH3+

26
Q

what the the amino group in its unprotonated form?

A

NH2

27
Q

what is special about the pKa form?

A

there is an equal amounts of both forms

28
Q

what is a zwitterion?

A

the dipolar ion of an amino group

29
Q

what is the isoelectric point (pi) of an amino acid?

A

where the net charge on the molecule is equal to 0

30
Q

what happens when you go through a buffering region?

A

lose a unit of positive charge

31
Q
A