Module 3 - Cells Flashcards

(52 cards)

1
Q

3 principle parts of cell

A

Plasma Membrane
Cytoplasm
Nucleus

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2
Q

Plasma Membrane

A

Flexible, sturdy barrier
Contains cytoplasm
Fluid mosaic model
Double layer (bilayer) of phospholipid molecules
Proteins dispersed throughout
Surface hydrophilic (loves water) – polar phosphate heads
Internal hydrophobic – nonpolar fatty acids
Integral proteins – firmly inserted – glycoproteins – serve as channels, transporters, and receptors, and enzymes
Peripheral proteins – loosely on inner and outer surface – serving as enzymes or cytoskeletal anchors
Cholesterol – stabilizes and reduces fluidity
Selectively permeable
Yes – small, nonpolar, uncharged molecules
No – ions, charged, or polar molecules
Transmembrane protein act as channels
Macromolecule use vesicular transport

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3
Q

Integral Proteins

A

Integral proteins – firmly inserted – glycoproteins – serve as channels, transporters, and receptors, and enzymes

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4
Q

Peripheral proteins

A

Peripheral proteins – loosely on inner and outer surface – serving as enzymes or cytoskeletal anchors

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5
Q

Cholesterol

A

Cholesterol – stabilizes and reduces fluidity

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6
Q

Parts of Cytoplasm

A

Cytosol
Cytoskeleton
Organelles

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7
Q

Cytosol

A

Cytosol – intracellular fluid
semi fluid – contains inclusions and dissolves solutes
mostly water, proteins, carbs, lipids, and inorganic substances
chemicals either in solution or colloidal (suspended) form
medium where metabolic reactions occur

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8
Q

Cytoskeleton

A

Microfilaments
Intermediate Filaments
Microtubules
Centrosomes
Cilia and Flagella

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9
Q

Microfilaments

A

Microfilaments – made of actin – function in movement and mechanical support

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10
Q

Intermediate filaments

A

Intermediate filaments – diff proteins – function to support and anchor organelles

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11
Q

Microtubules

A

Microtubules – protein called tubulin – determines cells shape – transports organelles – moves chromosomes during division

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12
Q

Centrosomes

A

Centrosomes – dense areas of cytoplasm containing centrioles – centers for organizing microtubules interphase and mitotic spindle during division

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13
Q

Cilia and Flagella

A

Cilia and Flagella – hair like projections from surface – move materials. Flagella – sperms

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14
Q

Ribosomes

A

Ribosomes or Synthesizer – consist of ribosomal RNA and ribosomal proteins – freely or in ER – synthesize proteins by building amino acids

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15
Q

Endoplasmic Reticulum

A

Endoplasmic Reticulum - STORAGE – network of membranes in flattened sacs (cisterns) – holds ribosomes and newly synthesized proteins – transports and stores – releases calcium for muscle contractions

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16
Q

Rough ER

A

Rough ER – continuous with nucleus – outer surface studded with ribosomes – synthesizes glycoproteins and fats

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17
Q

Smooth ER

A

Smooth ER – Extends from rough – network of tubules – no ribosomes on membrane – detoxes chemicals

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18
Q

Golgi Complex

A

Golgi Complex or SORTER – packages, processes, and delivers proteins sends to other places in cell – improves and fixes proteins from ER – forms vesicles to move molecules to membrane, exocytosis – tags things for location – Membrane, lysosomes, and secretory vesicles

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19
Q

Lysosomes

A

Lysosomes or Garbage Guts – cut or digest – membrane bound – digests molecules – formed in golgi complex – intracellular digestion – autophagy – worn out organelles – engulf structures – material can be reused

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20
Q

Peroxisomes

A

Peroxisomes – smaller than lysos – contain enzymes that oxidizes organic substances - lipid metabolism and catabolism of D-amino acids, polyamines and bile acids

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21
Q

Proteasome

A

Proteasome – tiny membrane bound sac that holds protease enzyme – cuts proteins

22
Q

Mitochondrion

A

Mitochondrion – double membrane bound – outer is smooth – inner has folds (cristae) – site of ATP productions by catabolism of nutrient molecules – aerobic cellular reaction – self replicating – own DNA

23
Q

Nucleus

A

Nucleus
Covered by nuclear envelope
Pores – nucleoli
Genetic material (DNA) arranged in single file along chromosomes
DNA is coiled with proteins
26 chromosomes in 23 pairs
Instructions for protein synthesis in DNA

24
Q

Transcription

A

Transcription – a section of DNA is copied onto strand of RNA – mRNA (messenger) – makes a template – directs protein synthesis – RNA polymerase comes to the section and opens it, elongation – the mRNA will leave the nucleus to find a ribosome - DNA synthesizes rRNA (ribosomal) and tRNA (transfer)

25
Translation
Translation – inside ribosome - mRNA acts as a code for specific protein – the template will code for its anticodon – carried by tRNA – initiator tRNA will line up with mRNA starter codons and begin bringing amino acids to grow the polypeptide chain with matching anti codons – mRNA is translated into protein that will dictate all actions and representations of genes
26
Cell Division
Cell Division Process of cell reproduction Mitosis, meiosis, and cytoplasmic division (cytokinesis)
27
Mitosis
Mitosis – increase body cells – nuclear division, with cytokinesis Distribution of two sets of chromosomes, one set for each nuclei
28
Meiosis
Meiosis – production of sperm and eggs
29
interphase
Normal cell life – interphase
30
Mitotic phases
Mitotic phases – Prophase, metaphase, anaphase, telophase, cytokinesis - PMAT
31
Prophase
Prophase: chromosomes condense in nucleus and become visible – become sister chromatids spindle fibers emerge from centrosomes nuclear envelope breaks down centrosomes move towards opposite poles
32
Metaphase
Metaphase: Centrosomes line up in middle – metaphase plate Each sister chromatid is attached to spindle fiber
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Anaphase
Anaphase: Centrosomes split Sister chromatids are split and dragged to opposite sides
34
Telophase
Telophase - Chromosomes go to opposite sides and begin decondensing Nuclear envelope begins to form around chromosomes Spindle pull nuclei to opposite ends
35
Cytokinesis
Cytokinesis: A cleavage furrow forms and separates nuclei
36
Active or passive Transport - cell movement
Transport Solutes = substances dissolved in a solvent Concentration gradient is difference concentrations of a substance b/w two areas
37
Vesicular Transport
Vesicular: Formation of membrane surrounded vesicles to move materials in or out of cell
38
Endocytosis
Endocytosis – particle too large to enter cell
39
Phagocytosis
Phagocytosis – large particles
40
Pinocytosis
Pinocytosis – fluid with solutes
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Receptor-mediated
Receptor-mediated
42
Exocytosis
Exocytosis – membrane encloses structure in cell and beings to surface for exit
43
Passive Transport
Passive Transport Non-mediated Mediated Diffusion Osmosis
44
Passive transport: Non-mediated
Non-mediated – diffusion through lipid bilayer or through channel
45
Passive transport- mediated
Mediated – facilitated diffusion Solute binds to transporter Conformational change Enters cell
46
Diffusion
Diffusion – random mixing of particles in a solution Steepness of concentration gradient Temperature Size or mass of substance Surface area Diffusion distance
47
Osmosis
Osmosis – diffusion of water thru a membrane Movement of water (solute) from high concentration to low
48
Osmosis - Tonicity of solution
Tonicity of solution – concentration in and out
49
Osmosis - Isotonic
Isotonic – same in and out
50
Osmosis - Hypotonic
Hypotonic – solutes outside less – solutes inside more – swell
51
Osmosis - Hypertonic
Hypertonic – solutes outside more – solutes inside less – shrink
52
Active Transport
Active Transport – energy needed to move solute against gradient Ions. Amino acids, and monosaccharides Pumps substances ATP Changes shape of transporter protein